Publications by authors named "Carlos Roca"

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Predictive value of bicarbonate levels at admission for severe hypoxic-ischemic encephalopathy after out-of-hospital cardiac arrest.
Marc Izquierdo Ribas, Teresa López-Sobrino, Eva Moreno, Oriol de Diego, Carlos Roca

Med Clin (Barc)· August 2025

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Systems vaccinology identifies immunological correlates of SARS-CoV-2 vaccine response in solid organ transplant recipients.
Nicolas Gemander, Julika Neumann, Rafael Veiga, Isabelle Etienne, Teresa Prezzemolo, Carlos P Roca

NPJ Vaccines· July 2025

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Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain.
Eva M García-Cuesta, Pablo Martínez, Karthik Selvaraju, Gabriel Ulltjärn, Adrián Miguel Gómez Pozo, Carlos Roca

Elife· September 2024

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The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program.
Oliver T Burton, Orian Bricard, Samar Tareen, Vaclav Gergelits, Simon Andrews, Carlos P Roca

Immunity· July 2024

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TiO nanoparticles' library toxicity (UV and non-UV exposure) - High-throughput in vivo transcriptomics reveals mechanisms.
Susana I L Gomes, Carlos P Roca, Suman Pokhrel, Lutz Mädler, Janeck J Scott-Fordsmand

NanoImpact· April 2023

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A cross entropy test allows quantitative statistical comparison of t-SNE and UMAP representations.
Carlos P Roca, Oliver T Burton, Julika Neumann, Samar Tareen, Carly E Whyte

Cell Rep Methods· January 2023

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Multitask Deep Neural Networks for Ames Mutagenicity Prediction.
María Jimena Martínez, María Virginia Sabando, Axel J Soto, Carlos Roca, Carlos Requena-Triguero

J Chem Inf Model· December 2022

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Correction: Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits.
Carly E Whyte, Kailash Singh, Oliver T Burton, Meryem Aloulou, Lubna Kouser, Carlos P Roca

J Exp Med· August 2022

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Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits.
Carly E Whyte, Kailash Singh, Oliver T Burton, Meryem Aloulou, Lubna Kouser, Carlos P Roca

J Exp Med· July 2022

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Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Lidia Yshii, Emanuela Pasciuto, Pascal Bielefeld, Loriana Mascali, Pierre Lemaitre, Carlos P Roca

Nat Immunol· June 2022

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AI in drug development: a multidisciplinary perspective.
Víctor Gallego, Roi Naveiro, Carlos Roca, David Ríos Insua, Nuria E Campillo

Mol Divers· August 2021

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AutoSpill is a principled framework that simplifies the analysis of multichromatic flow cytometry data.
Carlos P Roca, Oliver T Burton, Václav Gergelits, Teresa Prezzemolo, Carly E Whyte

Nat Commun· May 2021

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Glycogen synthase kinase 3 (GSK-3) inhibitors: a patent update (2016-2019).
Carlos Roca, Nuria E Campillo

Expert Opin Ther Pat· November 2020

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Increased IL-10-producing regulatory T cells are characteristic of severe cases of COVID-19.
Julika Neumann, Teresa Prezzemolo, Lore Vanderbeke, Carlos P Roca, Margaux Gerbaux

Clin Transl Immunology· November 2020

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Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Emanuela Pasciuto, Oliver T Burton, Carlos P Roca, Vasiliki Lagou, Wenson D Rajan

Cell· August 2020

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From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3).
Frédéric Lassagne, Camille Duguépéroux, Carlos Roca, Concepcion Perez, Ana Martinez

Org Biomol Chem· December 2019

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QSAR Classification Models for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer's Disease.
Ignacio Ponzoni, Víctor Sebastián-Pérez, María J Martínez, Carlos Roca, Carlos De la Cruz Pérez

Sci Rep· June 2019

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Machine learning identifies an immunological pattern associated with multiple juvenile idiopathic arthritis subtypes.
Erika Van Nieuwenhove, Vasiliki Lagou, Lien Van Eyck, James Dooley, Ulrich Bodenhofer, Carlos Roca

Ann Rheum Dis· May 2019

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NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology.
Susan Schlenner, Emanuela Pasciuto, Vasiliki Lagou, Oliver Burton, Teresa Prezzemolo, Carlos P Roca

Ann Rheum Dis· March 2019

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Indazolylketones as new multitarget cannabinoid drugs.
Pedro González-Naranjo, Natalia Pérez-Macias, Concepción Pérez, Carlos Roca, Gabriela Vaca

Eur J Med Chem· March 2019

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High-throughput transcriptomics: Insights into the pathways involved in (nano) nickel toxicity in a key invertebrate test species.
Susana I L Gomes, Carlos P Roca, Janeck J Scott-Fordsmand, Mónica J B Amorim

Environ Pollut· February 2019

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Murine myeloproliferative disorder as a consequence of impaired collaboration between dendritic cells and CD4 T cells.
Stéphanie Humblet-Baron, John S Barber, Carlos P Roca, Aurelie Lenaerts, Pandelakis A Koni

Blood· January 2019

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High-throughput gene expression in soil invertebrate embryos - Mechanisms of Cd toxicity in Enchytraeus crypticus.
Susana I L Gomes, Micael F M Gonçalves, Rita C Bicho, Carlos P Roca, Amadeu M V M Soares

Chemosphere· December 2018

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Mechanisms of (photo)toxicity of TiO nanomaterials (NM103, NM104, NM105): using high-throughput gene expression in Enchytraeus crypticus.
Susana I L Gomes, Carlos P Roca, Frank von der Kammer, Janeck J Scott-Fordsmand, Mónica J B Amorim

Nanoscale· November 2018

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Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.
Annachiara Gandini, Manuela Bartolini, Daniele Tedesco, Loreto Martinez-Gonzalez, Carlos Roca

J Med Chem· September 2018

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