Publications by authors named "Carole Phan"

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Live imaging and functional characterization of the avian hypoblast redefine the mechanisms of primitive streak induction.
Aurélien Villedieu, Olinda Alegria-Prévot, Carole Phan, Yu Ieda, Francis Corson

Nat Commun· November 2025

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IDO-1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension.
Zongye Cai, Ly Tu, Siyu Tian, Lin Deng, Yahong Fu, Carole Phan

J Am Heart Assoc· August 2025

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Self-organized tissue mechanics underlie embryonic regulation.
Paolo Caldarelli, Alexander Chamolly, Aurélien Villedieu, Olinda Alegria-Prévot, Carole Phan

Nature· September 2024

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Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells.
Benjamin Le Vely, Carole Phan, Nihel Berrebeh, Raphaël Thuillet, Mina Ottaviani

Am J Respir Cell Mol Biol· August 2022

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Serum and pulmonary uric acid in pulmonary arterial hypertension.
Laurent Savale, Satoshi Akagi, Ly Tu, Amélie Cumont, Raphaël Thuillet, Carole Phan

Eur Respir J· August 2021

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Neutralization of CXCL12 attenuates established pulmonary hypertension in rats.
Jennifer Bordenave, Raphaël Thuillet, Ly Tu, Carole Phan, Amélie Cumont

Cardiovasc Res· March 2020

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Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease.
Claire Bouvard, Nafiisha Genet, Carole Phan, Baptiste Rode, Raphaël Thuillet

Eur Respir J· March 2020

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Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension.
Paul-Benoit Poble, Carole Phan, Timothée Quatremare, Jennifer Bordenave, Raphaël Thuillet

FASEB J· March 2019

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Functional interaction between PDGFβ and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension.
Marceau Quatredeniers, Morad K Nakhleh, Sébastien J Dumas, Audrey Courboulin, Maria C Vinhas, Carole Phan

Am J Physiol Lung Cell Mol Physiol· March 2019

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Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension.
Ly Tu, Agnès Desroches-Castan, Christine Mallet, Laurent Guyon, Amélie Cumont, Carole Phan

Circ Res· March 2019

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[IL6R is the key therapeutical target in pulmonary arterial hypertension].
Ly Tu, Carole Phan, Marc Humbert, Christophe Guignabert

Med Sci (Paris)· October 2018

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Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension.
Tinne C J Mertens, Ankit Hanmandlu, Ly Tu, Carole Phan, Scott D Collum

Front Physiol· June 2018

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Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension.
Yuichi Tamura, Carole Phan, Ly Tu, Morane Le Hiress, Raphaël Thuillet

J Clin Invest· May 2018

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Design, Synthesis, and Biological Activity of New N-(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension.
Morane Le Hiress, Bernardin Akagah, Guillaume Bernadat, Ly Tu, Raphaël Thuillet, Carole Phan

J Med Chem· April 2018

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Dasatinib increases endothelial permeability leading to pleural effusion.
Carole Phan, Etienne-Marie Jutant, Ly Tu, Raphaël Thuillet, Andrei Seferian

Eur Respir J· January 2018

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[Towards new targets for the treatment of pulmonary arterial hypertension : Importance of cell-cell communications].
Ly Tu, Maria-Rosa Ghigna, Carole Phan, Jennifer Bordenave, Morane Le Hiress

Biol Aujourdhui· January 2017

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Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension.
Christophe Guignabert, Carole Phan, Andrei Seferian, Alice Huertas, Ly Tu, Stéphane Bouchet

J Clin Invest· September 2016

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Regulatory T Cell Dysfunction in Idiopathic, Heritable and Connective Tissue-Associated Pulmonary Arterial Hypertension.
Alice Huertas, Carole Phan, Jennifer Bordenave, Ly Tu, Raphaël Thuillet

Chest· June 2016

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Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex.
Morane Le Hiress, Ly Tu, Nicolas Ricard, Carole Phan, Raphaël Thuillet

Am J Respir Crit Care Med· October 2015

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Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension.
Véronique Freund-Michel, Marcelina Cardoso Dos Santos, Christophe Guignabert, David Montani, Carole Phan

Am J Respir Crit Care Med· August 2015

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Leptin signalling system as a target for pulmonary arterial hypertension therapy.
Alice Huertas, Ly Tu, Raphaël Thuillet, Morane Le Hiress, Carole Phan

Eur Respir J· April 2015

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Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle-like cells in pulmonary hypertension.
Nicolas Ricard, Ly Tu, Morane Le Hiress, Alice Huertas, Carole Phan

Circulation· April 2014

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