Publications by authors named "Caroline Austin"

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Impact of sickness induced by centrifugation on tilt perception.
Taylor L Lonner, Caroline R Austin, Joanna S Blake, Parinie Gupta, Jason M Katz

Front Neurol· September 2025

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Topoisomerase II DNA Cleavage Assay Using Fluorescently Labelled Double-Stranded Oligonucleotides.
Ian G Cowell, Elise M Ling, Caroline A Austin

Methods Mol Biol· May 2025

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Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection.
Jan Kubeš, Galina Karabanovich, Anh T Q Cong, Iuliia Melnikova, Olga Lenčová, Caroline A Austin

Nat Commun· May 2025

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TOP2B is required for compartment strength changes upon retinoic acid treatment in SH-SY5Y cells.
Erica M Hildebrand, Ian G Cowell, Mushtaq M Khazeem, Snehal Sambare, Ozgun Uyan, Caroline A Austin

Chromosome Res· April 2025

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Human perception of self-motion and orientation during galvanic vestibular stimulation and physical motion.
Aaron R Allred, Caroline R Austin, Lanna Klausing, Nicholas Boggess, Torin K Clark

PLoS Comput Biol· November 2024

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Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP2 poison anti-cancer drug etoposide.
Ian G Cowell, Caroline A Austin

FEBS Open Bio· June 2024

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Exploring the effects of topoisomerase II inhibitor XK469 on anthracycline cardiotoxicity and DNA damage.
Veronika Keresteš, Jan Kubeš, Lenka Applová, Petra Kollárová, Olga Lenčová-Popelová, Caroline A Austin

Toxicol Sci· March 2024

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XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes.
Georgia Chatzinikolaou, Kalliopi Stratigi, Athanasios Siametis, Evi Goulielmaki, Alexia Akalestou-Clocher, Caroline Austin

Sci Adv· November 2023

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To Break or Not to Break: The Role of TOP2B in Transcription.
Ian G Cowell, John W Casement, Caroline A Austin

Int J Mol Sci· September 2023

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DNA fragility at the / locus: insights from old and new technologies.
Ian G Cowell, Caroline A Austin

Open Biol· January 2023

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TOP2B Is Required to Maintain the Adrenergic Neural Phenotype and for ATRA-Induced Differentiation of SH-SY5Y Neuroblastoma Cells.
Mushtaq M Khazeem, John W Casement, George Schlossmacher, Niall S Kenneth, Nielda K Sumbung, Caroline A Austin

Mol Neurobiol· October 2022

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Two type I topoisomerases maintain DNA topology in human mitochondria.
Katja E Menger, James Chapman, Héctor Díaz-Maldonado, Mushtaq M Khazeem, Dasha Deen, Caroline A Austin

Nucleic Acids Res· October 2022

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A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193.
Elise M Ling, Arnaud Baslé, Ian G Cowell, Bert van den Berg, Tim R Blower, Caroline A Austin

Structure· August 2022

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Subsensory electrical noise stimulation applied to the lower trunk improves postural control during visual perturbations.
Zahra Bassiri, Caroline Austin, Christian Cousin, Dario Martelli

Gait Posture· July 2022

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Disease-associated mutations in topoisomerase IIβ result in defective NK cells.
Lori Broderick, Gwendolyn M Clay, Robert H Blum, Yang Liu, Rachael McVicar, Caroline A Austin

J Allergy Clin Immunol· June 2022

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Human topoisomerases and their roles in genome stability and organization.
Yves Pommier, André Nussenzweig, Shunichi Takeda, Caroline Austin

Nat Rev Mol Cell Biol· June 2022

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The Precariat and the Pandemic: Assessing the Well-Being of Metro Orlando's Hospitality Workers During the COVID-19 Pandemic.
Caroline Austin, Amy Donley

Sociol Inq· June 2022

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Mechanisms to Repair Stalled Topoisomerase II-DNA Covalent Complexes.
Rebecca L Swan, Ian G Cowell, Caroline A Austin

Mol Pharmacol· January 2022

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TOP2B's contributions to transcription.
Caroline A Austin, Ian G Cowell, Mushtaq M Khazeem, Dawn Lok, Huei Teng Ng

Biochem Soc Trans· December 2021

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A Role for VCP/p97 in the Processing of Drug-Stabilized TOP2-DNA Covalent Complexes.
Rebecca L Swan, Ian G Cowell, Caroline A Austin

Mol Pharmacol· July 2021

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Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions.
Anna Jirkovská, Galina Karabanovich, Jan Kubeš, Veronika Skalická, Iuliia Melnikova, Caroline A Austin

J Med Chem· April 2021

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Transcription of carbonyl reductase 1 is regulated by DNA topoisomerase II beta.
Mushtaq M Khazeem, Ian G Cowell, Lauren F Harkin, John W Casement, Caroline A Austin

FEBS Lett· October 2020

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Small Molecule Inhibitors Confirm Ubiquitin-Dependent Removal of TOP2-DNA Covalent Complexes.
Rebecca L Swan, Luke L K Poh, Ian G Cowell, Caroline A Austin

Mol Pharmacol· September 2020

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The Deubiquitinating Enzyme Inhibitor PR-619 is a Potent DNA Topoisomerase II Poison.
Ian G Cowell, Elise M Ling, Rebecca L Swan, Matilda L W Brooks, Caroline A Austin

Mol Pharmacol· November 2019

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Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.
Suguru Morimoto, Masataka Tsuda, Heeyoun Bunch, Hiroyuki Sasanuma, Caroline Austin

Genes (Basel)· October 2019

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