Publications by authors named "Caroline Chilton"

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Clostridioides difficile pathogenesis and control.
Caroline H Chilton, Virginie Viprey, Charmaine Normington, Ines B Moura, Anthony M Buckley

Nat Rev Microbiol· October 2025

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Perioperative changes in the microbiome during rectal cancer surgery: exploratory analysis of the National Institute for Health and Care Research (NIHR) IntAct trial.
Jack A Helliwell, Caroline H Chilton, Caroline Young, Emma V Clark, Lyndsay Wilkinson

Br J Surg· September 2025

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Clostridioides difficile Biofilm.
Claudia Vuotto, Gianfranco Donelli, Anthony Buckley, Caroline Chilton

Adv Exp Med Biol· February 2024

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Clostridioides difficile infections; new treatments and future perspectives.
Charmaine Normington, Caroline H Chilton, Anthony M Buckley

Curr Opin Gastroenterol· January 2024

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Optimization of an Assay To Determine Colonization Resistance to Clostridioides difficile in Fecal Samples from Healthy Subjects and Those Treated with Antibiotics.
Hannah C Harris, Emma L Best, Charmaine Normington, Nathalie Saint-Lu, Frédérique Sablier-Gallis, Caroline H Chilton

Antimicrob Agents Chemother· December 2020

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A Novel, Orally Delivered Antibody Therapy and Its Potential to Prevent Infection in Pre-clinical Models.
April K Roberts, Hannah C Harris, Michael Smith, Joanna Giles, Oktawia Polak, Caroline Chilton

Front Microbiol· September 2020

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Method comparison for the direct enumeration of bacterial species using a chemostat model of the human colon.
Ines B Moura, Charmaine Normington, Duncan Ewin, Emma Clark, Mark H Wilcox, Caroline H Chilton

BMC Microbiol· January 2020

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Omadacycline Gut Microbiome Exposure Does Not Induce Clostridium difficile Proliferation or Toxin Production in a Model That Simulates the Proximal, Medial, and Distal Human Colon.
Ines B Moura, Anthony M Buckley, Duncan Ewin, Sharie Shearman, Emma Clark, Caroline H Chilton

Antimicrob Agents Chemother· February 2019

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Clostridium difficile Biofilm.
Claudia Vuotto, Gianfranco Donelli, Anthony Buckley, Caroline Chilton

Adv Exp Med Biol· June 2018

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An In Vitro Model of the Human Colon: Studies of Intestinal Biofilms and Clostridium difficile Infection.
Grace S Crowther, Mark H Wilcox, Caroline H Chilton

Methods Mol Biol· January 2018

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Association of Fidaxomicin with C. difficile Spores: Effects of Persistence on Subsequent Spore Recovery, Outgrowth and Toxin Production.
Caroline H Chilton, Grace S Crowther, Helen Ashwin, Chris M Longshaw, Mark H Wilcox

PLoS One· July 2017

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Efficacy of vancomycin extended-dosing regimens for treatment of simulated Clostridium difficile infection within an in vitro human gut model.
Grace S Crowther, Caroline H Chilton, Chris Longshaw, Sharie L Todhunter, Duncan Ewin

J Antimicrob Chemother· April 2016

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Recurrence of dual-strain Clostridium difficile infection in an in vitro human gut model.
Grace S Crowther, Caroline H Chilton, Sharie L Todhunter, Scott Nicholson, Jane Freeman

J Antimicrob Chemother· August 2015

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Predictive values of models of Clostridium difficile infection.
Caroline H Chilton, Jane Freeman

Infect Dis Clin North Am· March 2015

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Development and validation of a chemostat gut model to study both planktonic and biofilm modes of growth of Clostridium difficile and human microbiota.
Grace S Crowther, Caroline H Chilton, Sharie L Todhunter, Scott Nicholson, Jane Freeman

PLoS One· January 2015

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Comparison of planktonic and biofilm-associated communities of Clostridium difficile and indigenous gut microbiota in a triple-stage chemostat gut model.
Grace S Crowther, Caroline H Chilton, Sharie L Todhunter, Scott Nicholson, Jane Freeman

J Antimicrob Chemother· August 2014

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Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease.
David W Eyre, A Sarah Walker, Jane Freeman, Simon D Baines, Warren N Fawley, Caroline H Chilton

PLoS One· January 2014

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Evaluation of antimicrobial activity of ceftaroline against Clostridium difficile and propensity to induce C. difficile infection in an in vitro human gut model.
Simon D Baines, Caroline H Chilton, Grace S Crowther, Sharie L Todhunter, Jane Freeman

J Antimicrob Chemother· August 2013

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Mixed infection by Clostridium difficile in an in vitro model of the human gut.
Simon D Baines, Grace S Crowther, Sharie L Todhunter, Jane Freeman, Caroline H Chilton

J Antimicrob Chemother· May 2013

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Evaluation of NVB302 versus vancomycin activity in an in vitro human gut model of Clostridium difficile infection.
Grace S Crowther, Simon D Baines, Sharie L Todhunter, Jane Freeman, Caroline H Chilton

J Antimicrob Chemother· January 2013

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Oritavancin does not induce Clostridium difficile germination and toxin production in hamsters or a human gut model.
Jane Freeman, Miriam Marquis, Grace S Crowther, Sharie L Todhunter, Warren N Fawley, Caroline H Chilton

J Antimicrob Chemother· December 2012

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Co-amoxiclav induces proliferation and cytotoxin production of Clostridium difficile ribotype 027 in a human gut model.
Caroline H Chilton, Jane Freeman, Grace S Crowther, Sharie L Todhunter, Scott Nicholson

J Antimicrob Chemother· April 2012

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