Publications by authors named "Caroline Hick"

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Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors.
Jianjun Cao, Matthew J Belousoff, Rachel M Johnson, Peter Keov, Zamara Mariam, Caroline A Hick

Nat Commun· April 2025

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Isoquinoline small molecule ligands are agonists and probe-dependent allosteric modulators of the glucagon subfamily of GPCRs.
Elita Yuliantie, Phuc Nh Trinh, Caroline Hick, Rebecca Ebenhoch, Herbert Nar

Biochem Pharmacol· November 2024

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Development of a Novel Assay for Direct Assessment of Selective Amylin Receptor Activation Reveals Novel Differences in Behavior of Selective and Nonselective Peptide Agonists.
Peter Keov, George Christopoulos, Caroline A Hick, Tine Glendorf, Borja Ballarín-González

Mol Pharmacol· April 2024

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High-Throughput Screening to Identify Inhibitors of Importin α.
Sujata B Walunj, Manisha M Dias, Chhaminder Kaur, Kylie M Wagstaff, Vishakha Dey, Caroline Hick

Cells· April 2022

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AM833 Is a Novel Agonist of Calcitonin Family G Protein-Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists.
Madeleine M Fletcher, Peter Keov, Tin T Truong, Grace Mennen, Caroline A Hick

J Pharmacol Exp Ther· June 2021

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Deconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor.
Vi Pham, Yue Zhu, Emma Dal Maso, Christopher A Reynolds, Giuseppe Deganutti, Caroline A Hick

ACS Pharmacol Transl Sci· June 2019

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The Molecular Control of Calcitonin Receptor Signaling.
Emma Dal Maso, Alisa Glukhova, Yue Zhu, Javier Garcia-Nafria, Christopher G Tate, Caroline A Hick

ACS Pharmacol Transl Sci· February 2019

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Expression and activity of the calcitonin receptor family in a sample of primary human high-grade gliomas.
Anna Ostrovskaya, Caroline Hick, Dana S Hutchinson, Brett W Stringer, Peter J Wookey

BMC Cancer· February 2019

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Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy.
Emma Dal Maso, Yue Zhu, Vi Pham, Christopher A Reynolds, Giuseppe Deganutti, Caroline A Hick

Biochem Pharmacol· April 2018

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Identification of novel antivirals inhibiting recognition of Venezuelan equine encephalitis virus capsid protein by the Importin α/β1 heterodimer through high-throughput screening.
David R Thomas, Lindsay Lundberg, Chelsea Pinkham, Sharon Shechter, Aaron DeBono, Caroline A Hick

Antiviral Res· March 2018

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Characterization of signalling and regulation of common calcitonin receptor splice variants and polymorphisms.
Emma Dal Maso, Rasmus Just, Caroline Hick, Arthur Christopoulos, Patrick M Sexton

Biochem Pharmacol· February 2018

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Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R).
Cassandra Koole, Christopher A Reynolds, Juan C Mobarec, Caroline Hick, Patrick M Sexton

J Biol Chem· April 2017

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Privileging place: Reflections on involving people with dementia in a residency.
Ruth Bartlett, Caroline Hick, Agnes Houston, Larry Gardiner, Daphne Wallace

Dementia (London)· November 2015

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A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.
Johanna E Fraser, Satoru Watanabe, Chunxiao Wang, Wing Ki Kitti Chan, Belinda Maher, Caroline Hick

J Infect Dis· December 2014

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Analysis of human Nav1.8 expressed in SH-SY5Y neuroblastoma cells.
Lodewijk V Dekker, Zoe Daniels, Caroline Hick, Kathryn Elsegood, Sarah Bowden

Eur J Pharmacol· December 2005

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Heterologous expression and functional analysis of rat Nav1.8 (SNS) voltage-gated sodium channels in the dorsal root ganglion neuroblastoma cell line ND7-23.
Victoria H John, Martin J Main, Andrew J Powell, Zoe M Gladwell, Caroline Hick

Neuropharmacology· March 2004

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