Publications by authors named "Caroline Jan"

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Loss of the neuronal kinase DCLK3 leads to anxiety-like behaviour and memory deficits.
Lucie de Longprez, Marie-Claude Gaillard, Charles Decraene, Jean-Baptiste Pérot, Céline Keime, Caroline Jan

Brain· July 2025

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Hippocampal Astrocyte Morphology Follows an Unexpected Trajectory With Age in a Transgenic Rodent Model of Tauopathy.
Emma Augustin, Tatiana Vinasco-Sandoval, Miriam Riquelme-Perez, Damien Plassard, Mylène Gaudin, Caroline Jan

Glia· July 2025

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Selective, Non-nucleotidic Radiotracer for P2Y Receptors: Design, Synthesis, Characterization, and Imaging of Brain Slices.
Haneen Al-Hroub, Hashem Ali M Al Musawi, Aliaa Abdelrahman, Vigneshwaran Namasivayam, Margot Corbel, Caroline Jan

J Med Chem· June 2025

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Noninvasive Imaging of Transgene Expression in Neurons Using Chemical Exchange Saturation Transfer MRI.
Julien Flament, Jérémy Pépin, Marianne Maugard, Mylène Gaudin, Léa Cohen, Caroline Jan

NMR Biomed· March 2025

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giRAff: an automated atlas segmentation tool adapted to single histological slices.
Sébastien Piluso, Nicolas Souedet, Caroline Jan, Anne-Sophie Hérard, Cédric Clouchoux

Front Neurosci· January 2024

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Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology.
Charlotte Duwat, Pauline Léal, Audrey Vautheny, Gwennaëlle Aurégan, Charlène Joséphine, Caroline Jan

Neurobiol Dis· June 2023

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Functional and neuropathological changes induced by injection of distinct alpha-synuclein strains: A pilot study in non-human primates.
Audrey Fayard, Alexis Fenyi, Sonia Lavisse, Sandra Dovero, Luc Bousset, Caroline Jan

Neurobiol Dis· May 2023

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A general deep learning framework for neuron instance segmentation based on Efficient UNet and morphological post-processing.
Huaqian Wu, Nicolas Souedet, Caroline Jan, Cédric Clouchoux, Thierry Delzescaux

Comput Biol Med· November 2022

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Automated Atlas-based Segmentation of Single Coronal Mouse Brain Slices using Linear 2D-2D Registration.
Sebastien Piluso, Nicolas Souedet, Caroline Jan, Cedric Clouchoux, Thierry Delzescaux

Annu Int Conf IEEE Eng Med Biol Soc· November 2021

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Evaluation of Deep Learning Topcoders Method for Neuron Individualization in Histological Macaque Brain Section.
Huaqian Wu, Nicolas Souedet, Zhenzhen You, Caroline Jan, Cedric Clouchoux

Annu Int Conf IEEE Eng Med Biol Soc· November 2021

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Evaluation of automated segmentation algorithms for neurons in macaque cerebral microscopic images.
Zhenzhen You, Ming Jiang, Zhenghao Shi, Xiaojuan Ning, Cheng Shi, Caroline Jan

Microsc Res Tech· October 2021

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THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency.
Audrey Vautheny, Charlotte Duwat, Gwennaëlle Aurégan, Charlène Joséphine, Anne-Sophie Hérard, Caroline Jan

Neurobiol Dis· July 2021

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The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo.
Noémie Cresto, Camille Gardier, Marie-Claude Gaillard, Francesco Gubinelli, Pauline Roost, Caroline Jan

Int J Mol Sci· June 2021

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Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state.
Anastasie Maté de Gérando, Marie d'Orange, Emma Augustin, Charlène Joséphine, Gwénaelle Aurégan, Caroline Jan

Brain· May 2021

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Complete spatial characterisation of N-glycosylation upon striatal neuroinflammation in the rodent brain.
Ana Lúcia Rebelo, Francesco Gubinelli, Pauline Roost, Caroline Jan, Emmanuel Brouillet

J Neuroinflammation· May 2021

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Assessment of simplified methods for quantification of [F]-DPA-714 using 3D whole-brain TSPO immunohistochemistry in a non-human primate.
Nadja Van Camp, Yaël Balbastre, Anne-Sophie Herard, Sonia Lavisse, Clovis Tauber, Caroline Jan

J Cereb Blood Flow Metab· May 2020

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The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo.
Noémie Cresto, Marie-Claude Gaillard, Camille Gardier, Francesco Gubinelli, Elsa Diguet, Caroline Jan

Neurobiol Dis· February 2020

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Tridimensional mapping of Phox2b expressing neurons in the brainstem of adult Macaca fascicularis and identification of the retrotrapezoid nucleus.
Jonathan Levy, Patricia Facchinetti, Caroline Jan, Mélyna Achour, Clément Bouvier

J Comp Neurol· December 2019

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Automated Individualization of Size-Varying and Touching Neurons in Macaque Cerebral Microscopic Images.
Zhenzhen You, Yaël Balbastre, Clément Bouvier, Anne-Sophie Hérard, Pauline Gipchtein, Caroline Jan

Front Neuroanat· December 2019

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Longitudinal characterization of cognitive and motor deficits in an excitotoxic lesion model of striatal dysfunction in non-human primates.
Sonia Lavisse, Susannah Williams, Sophie Lecourtois, Nadja van Camp, Martine Guillermier, Caroline Jan

Neurobiol Dis· October 2019

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Gene Therapy for Parkinson's Disease: Preclinical Evaluation of Optimally Configured TH:CH1 Fusion for Maximal Dopamine Synthesis.
Romina Aron Badin, Katie Binley, Nadja Van Camp, Caroline Jan, Jeanne Gourlay

Mol Ther Methods Clin Dev· September 2019

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MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates.
Romina Aron Badin, Aurore Bugi, Susannah Williams, Marta Vadori, Marie Michael, Caroline Jan

Nat Commun· September 2019

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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Laurie Galvan, Laetitia Francelle, Marie-Claude Gaillard, Lucie de Longprez, Maria-Angeles Carrillo-de Sauvage, Caroline Jan

Brain· May 2018

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Three-dimensional SPACE fluid-attenuated inversion recovery at 3 T to improve subthalamic nucleus lead placement for deep brain stimulation in Parkinson's disease: from preclinical to clinical studies.
Suhan Senova, Koichi Hosomi, Jean-Marc Gurruchaga, Gaëtane Gouello, Naoufel Ouerchefani, Caroline Jan

J Neurosurg· August 2016

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Synaptic scaling up in medium spiny neurons of aged BACHD mice: A slow-progression model of Huntington's disease.
Anne B Rocher, Paolo Gubellini, Nicolas Merienne, Lydie Boussicault, Fanny Petit, Caroline Jan

Neurobiol Dis· February 2016

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