Publications by authors named "Carson Flamm"

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γ-Aminobutyric acid transporter and GABA receptor mechanisms in and mice associated with developmental and epileptic encephalopathies.
Wangzhen Shen, Gerald Nwosu, Michael Honer, Jerome Clasadonte, Svenja Schmalzbauer, Carson Flamm

Brain Commun· April 2024

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Modulating Endoplasmic Reticulum Chaperones and Mutant Protein Degradation in GABRG2(Q390X) Associated with Genetic Epilepsy with Febrile Seizures Plus and Dravet Syndrome.
Sarah Poliquin, Gerald Nwosu, Karishma Randhave, Wangzhen Shen, Carson Flamm

Int J Mol Sci· April 2024

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4-Phenylbutyrate promoted wild-type γ-aminobutyric acid type A receptor trafficking, reduced endoplasmic reticulum stress, and mitigated seizures in Gabrg2 mice associated with Dravet syndrome.
Wangzhen Shen, Carson Flamm, Aiden J Delahanty, Emmett Casteel, Marshall Biven

Epilepsia· January 2024

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GABA Receptor β3 Subunit Mutation N328D Heterozygous Knock-in Mice Have Lennox-Gastaut Syndrome.
Gerald Ikemefuna Nwosu, Wangzhen Shen, Kirill Zavalin, Sarah Poliquin, Karishma Randhave, Carson Flamm

Int J Mol Sci· May 2023

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Heterozygous GABA receptor β3 subunit N110D knock-in mice have epileptic spasms.
Shimian Qu, Laurel G Jackson, Chengwen Zhou, DingDing Shen, Wangzhen Shen, Carson Flamm

Epilepsia· April 2023

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Astrocytic GABA transporter 1 deficit in novel SLC6A1 variants mediated epilepsy: Connected from protein destabilization to seizures in mice and humans.
Felicia Mermer, Sarah Poliquin, Shuizhen Zhou, Xiaodong Wang, Yifeng Ding, Carson Flamm

Neurobiol Dis· October 2022

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4-Phenylbutyrate restored γ-aminobutyric acid uptake and reduced seizures in patient variant-bearing cell and mouse models.
Gerald Nwosu, Felicia Mermer, Carson Flamm, Sarah Poliquin, Wangzhen Shen

Brain Commun· June 2022

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Endoplasmic reticulum retention and degradation of a mutation in SLC6A1 associated with epilepsy and autism.
Jie Wang, Sarah Poliquin, Felicia Mermer, Jaclyn Eissman, Eric Delpire, Carson Flamm

Mol Brain· May 2020

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