Publications by authors named "Carsten Alt"

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Discovery of Osivelotor (GBT021601): A Potent, Next-Generation Sickle Hemoglobin Polymerization Inhibitor.
Zhe Li, Carsten Alt, Kobina Dufu, Athiwat Hutchaleelaha, Qing Xu

ACS Med Chem Lett· August 2025

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Red blood cell pyruvate kinase properties in Townes and Berkeley sickle cell disease mouse models - Of mice and men.
Marissa J M Traets, Titine J J Ruiter, Charles Levine, Anita W Rijneveld, Judith J Jans, Carsten Alt

Blood Cells Mol Dis· March 2025

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GBT021601 improves red blood cell health and the pathophysiology of sickle cell disease in a murine model.
Kobina Dufu, Carsten Alt, Steven Strutt, James Partridge, Tzechiang Tang

Br J Haematol· July 2023

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Increased hemoglobin affinity for oxygen with GBT1118 improves hypoxia tolerance in sickle cell mice.
Kobina Dufu, Alexander T Williams, Cynthia R Muller, Cynthia M Walser, Alfredo Lucas, Carsten Alt

Am J Physiol Heart Circ Physiol· August 2021

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Long-Acting IL-33 Mobilizes High-Quality Hematopoietic Stem and Progenitor Cells More Efficiently Than Granulocyte Colony-Stimulating Factor or AMD3100.
Carsten Alt, Shujun Yuan, Faye Wu, Basha Stankovich, Joy Calaoagan

Biol Blood Marrow Transplant· August 2019

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Non-reducible disulfide bond replacement implies that disulfide exchange is not required for hepcidin-ferroportin interaction.
Dong-Liang Huang, Jing-Si Bai, Meng Wu, Xia Wang, Bernd Riedl, Carsten Alt

Chem Commun (Camb)· February 2019

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Prophylactic treatment with a novel bioadhesive gel formulation containing aciclovir and tenofovir protects from HSV-2 infection.
Gita N Shankar, Carsten Alt

J Antimicrob Chemother· December 2014

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Associations between in vivo neuroimaging and postmortem brain cytokine markers in a rodent model of Wernicke's encephalopathy.
Natalie M Zahr, Carsten Alt, Dirk Mayer, Torsten Rohlfing, Amy Manning-Bog

Exp Neurol· November 2014

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Formulation development and evaluation of innovative two-polymer (SR-2P) bioadhesive vaginal gel.
Satheesh Podaralla, Carsten Alt, Gita N Shankar

AAPS PharmSciTech· August 2014

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DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation.
Carsten Minten, Carsten Alt, Melanie Gentner, Elisabeth Frei, Urban Deutsch

Brain· May 2014

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The skin, a novel niche for recirculating B cells.
Skye A Geherin, Sarah R Fintushel, Michael H Lee, R Paul Wilson, Reema T Patel, Carsten Alt

J Immunol· June 2012

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Nociceptin/orphanin FQ inhibition with SB612111 ameliorates dextran sodium sulfate-induced colitis.
Carsten Alt, Jennifer S Lam, M Travis Harrison, Kathleen M Kershaw, Steven Samuelsson

Eur J Pharmacol· May 2012

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SR16388: a steroidal antiangiogenic agent with potent inhibitory effect on tumor growth in vivo.
Wan-Ru Chao, Khalid Amin, Yihui Shi, Peter Hobbs, Mas Tanabe, Carsten Alt

Angiogenesis· March 2011

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Increased CCL2 expression and macrophage/monocyte migration during microbicide-induced vaginal irritation.
Carsten Alt, Travis Harrison, Linda Dousman, Nahoko Fujita, Ken Shew

Curr HIV Res· November 2009

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Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis.
Brian A Zabel, Susumu Nakae, Luis Zúñiga, Ji-Yun Kim, Takao Ohyama, Carsten Alt

J Exp Med· September 2008

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L-Selectin-deficient SJL and C57BL/6 mice are not resistant to experimental autoimmune encephalomyelitis.
Chiara Uboldi, Axinia Döring, Carsten Alt, Pila Estess, Mark Siegelman

Eur J Immunol· August 2008

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DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27.
Hekla Sigmundsdottir, Junliang Pan, Gudrun F Debes, Carsten Alt, Aida Habtezion

Nat Immunol· March 2007

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Gene and protein expression profiling of the microvascular compartment in experimental autoimmune encephalomyelitis in C57Bl/6 and SJL mice.
Carsten Alt, Kristina Duvefelt, Bo Franzén, Yang Yang, Britta Engelhardt

Brain Pathol· January 2005

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Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalomyelitis.
Carsten Alt, Melanie Laschinger, Britta Engelhardt

Eur J Immunol· August 2002

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