Publications by authors named "Carsten Kirschning"

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Combining antibiotic with anti-TLR2/TLR13 therapy prevents brain pathology in pneumococcal meningitis.
Susanne Dyckhoff-Shen, Ilias Masouris, Heba Islam, Sven Hammerschmidt, Barbara Angele, Carsten J Kirschning

JCI Insight· February 2024

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TLR2 mediates renal apoptosis in neonatal mice subjected experimentally to obstructive nephropathy.
Maja Wyczanska, Jana Rohling, Ursula Keller, Marcus R Benz, Carsten Kirschning

PLoS One· December 2023

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Substantial heterogeneity of inflammatory cytokine production and its inhibition by a triple cocktail of toll-like receptor blockers in early sepsis.
Willem Buys, Alexandra Bick, Rabea J Madel, Astrid M Westendorf, Jan Buer, Carsten J Kirschning

Front Immunol· November 2023

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Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model.
Rabea J Madel, Verena Börger, Robin Dittrich, Michel Bremer, Tobias Tertel, Carsten J Kirschning

Cytotherapy· August 2023

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The role of plasminogen activator inhibitor-2 in pneumococcal meningitis.
Nina C Teske, Joo-Yeon Engelen-Lee, Susanne Dyckhoff-Shen, Hans-Walter Pfister, Matthias Klein, Carsten K Kirschning

Acta Neuropathol Commun· October 2022

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Immune hyporeactivity to bacteria and multiple TLR-ligands, yet no response to checkpoint inhibition in patients just after meeting Sepsis-3 criteria.
Alexandra Bick, Willem Buys, Andrea Engler, Rabea Madel, Mazen Atia, Carsten J Kirschning

PLoS One· August 2022

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Editorial: Patho- and Physiological Roles of Inflammasomes.
Guangxun Meng, Carsten J Kirschning, Rongbin Zhou

Front Immunol· May 2022

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The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells Activating the TLR4 Signaling Pathway.
Xiaoli Yang, Shafaqat Ali, Manman Zhao, Lisa Richter, Vanessa Schäfer, Carsten Kirschning

Front Immunol· April 2022

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CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells.
Camilla Wilk, Laura Effenberg, Hanna Abberger, Laura Steenpass, Wiebke Hansen, Carsten Kirschning

Cell Immunol· January 2022

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Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life.
Artur Kibler, Bettina Budeus, Ekaterina Homp, Kevin Bronischewski, Victoria Berg, Carsten J Kirschning

J Exp Med· April 2021

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Hepatitis B virus particles activate B cells through the TLR2-MyD88-mTOR axis.
Qian Li, Jun Wang, Heba Islam, Carsten Kirschning, Hongzhou Lu

Cell Death Dis· January 2021

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Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis.
Qian Li, Yan Yan, Jia Liu, Xuan Huang, Xiaoyong Zhang, Carsten Kirschning

Front Immunol· November 2020

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TLR2 Stimulation Increases Cellular Metabolism in CD8 T Cells and Thereby Enhances CD8 T Cell Activation, Function, and Antiviral Activity.
Ejuan Zhang, Zhiyong Ma, Qian Li, Hu Yan, Jia Liu, Carsten J Kirschning

J Immunol· December 2019

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Melanoma Extracellular Vesicles Generate Immunosuppressive Myeloid Cells by Upregulating PD-L1 via TLR4 Signaling.
Viktor Fleming, Xiaoying Hu, Céline Weller, Rebekka Weber, Christopher Groth, Carsten Kirschning

Cancer Res· September 2019

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Circulating growth/differentiation factor 15 is associated with human CD56 natural killer cell dysfunction and nosocomial infection in severe systemic inflammation.
Holger Kleinertz, Monika Hepner-Schefczyk, Sabrina Ehnert, Maren Claus, Rebecca Halbgebauer, Carsten Kirschning

EBioMedicine· May 2019

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Glycosylation of HIV Env Impacts IgG Subtype Responses to Vaccination.
Rebecca Heß, Michael Storcksdieck Genannt Bonsmann, Dennis Lapuente, Andre Maaske, Carsten Kirschning

Viruses· February 2019

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Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells.
Kourosh Gharun, Julia Senges, Maximilian Seidl, Anne Lösslein, Julia Kolter, Carsten J Kirschning

EMBO Rep· December 2018

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Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia.
Oliver H Robak, Markus M Heimesaat, Andrey A Kruglov, Sandra Prepens, Justus Ninnemann, Carsten J Kirschning

J Clin Invest· August 2018

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Stimulates TLR2-PI3K Signaling to Escape Immune Clearance and Induce Bone Resorption Independently of MyD88.
Hasnaa Makkawi, Shifra Hoch, Elia Burns, Kavita Hosur, George Hajishengallis, Carsten J Kirschning

Front Cell Infect Microbiol· April 2018

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The IL-1R/TLR signaling pathway is essential for efficient CD8 T-cell responses against hepatitis B virus in the hydrodynamic injection mouse model.
Zhiyong Ma, Jia Liu, Weimin Wu, Ejuan Zhang, Xiaoyong Zhang, Carsten J Kirschning

Cell Mol Immunol· December 2017

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Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells.
Kourosh Gharun, Julia Senges, Maximilian Seidl, Anne Lösslein, Julia Kolter, Carsten J Kirschning

EMBO Rep· December 2017

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Decreased Secondary Lesion Growth and Attenuated Immune Response after Traumatic Brain Injury in Mice.
Sandro M Krieg, Florian Voigt, Pascal Knuefermann, Carsten Jürgen Kirschning, Nikolaus Plesnila

Front Neurol· August 2017

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Toll-Like Receptor 2 and Mincle Cooperatively Sense Corynebacterial Cell Wall Glycolipids.
Judith Schick, Philipp Etschel, Rebeca Bailo, Lisa Ott, Apoorva Bhatt, Carsten Kirschning

Infect Immun· July 2017

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Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth.
Johanna C Klein, Katrin Moses, Gennadiy Zelinskyy, Simon Sody, Jan Buer, Carsten J Kirschning

Nat Commun· March 2017

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RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production.
Sathish Kumar Maney, Haifeng C Xu, Jun Huang, Aleksandra A Pandyra, Christian Ehlting, Carsten J Kirschning

Cell Physiol Biochem· January 2017

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