Publications by authors named "Carsten Merkwirth"

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IL-2 Complexed With Anti-IL-2 Antibody Expands the Maternal T-Regulatory Cell Pool and Alleviates Fetal Loss in Abortion-Prone Mice.
Kerrie L Foyle, Peck Y Chin, Carsten Merkwirth, Jasmine Wilson, Shanna L Hosking

Am J Pathol· November 2024

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Mezagitamab in systemic lupus erythematosus: clinical and mechanistic findings of CD38 inhibition in an autoimmune disease.
Scott R P McDonnell, Van Anh Nguyen, Noah M Walton, Carsten Merkwirth, Feng Hong

Lupus Sci Med· March 2024

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Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance.
Jennifer L Green, Robin E Osterhout, Amy L Klova, Carsten Merkwirth, Scott R P McDonnell

Mol Ther Oncolytics· December 2021

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Mitochondrial UPR: A Double-Edged Sword.
Ye Tian, Carsten Merkwirth, Andrew Dillin

Trends Cell Biol· August 2016

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Signaling Networks Determining Life Span.
Celine E Riera, Carsten Merkwirth, C Daniel De Magalhaes Filho, Andrew Dillin

Annu Rev Biochem· June 2016

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Prohibitin-2 Depletion Unravels Extra-Mitochondrial Functions at the Kidney Filtration Barrier.
Christina Ising, Puneet Bharill, Sibylle Brinkkoetter, Sebastian Brähler, Christina Schroeter, Carsten Merkwirth

Am J Pathol· May 2016

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Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.
Carsten Merkwirth, Virginija Jovaisaite, Jenni Durieux, Olli Matilainen, Sabine D Jordan

Cell· May 2016

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Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria.
Anne Korwitz, Carsten Merkwirth, Ricarda Richter-Dennerlein, Simon E Tröder, Hans-Georg Sprenger

J Cell Biol· January 2016

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Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice.
Timothy Wai, Jaime García-Prieto, Michael J Baker, Carsten Merkwirth, Paule Benit

Science· December 2015

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Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure.
Christina Ising, Sybille Koehler, Sebastian Brähler, Carsten Merkwirth, Martin Höhne

EMBO Mol Med· March 2015

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TRPV1 pain receptors regulate longevity and metabolism by neuropeptide signaling.
Céline E Riera, Mark O Huising, Patricia Follett, Mathias Leblanc, Jonathan Halloran, Carsten Merkwirth

Cell· May 2014

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Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development.
Sachin Supale, Fabrizio Thorel, Carsten Merkwirth, Asllan Gjinovci, Pedro L Herrera

Diabetes· October 2013

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FOXO4 is necessary for neural differentiation of human embryonic stem cells.
David Vilchez, Leah Boyer, Margaret Lutz, Carsten Merkwirth, Ianessa Morantte

Aging Cell· June 2013

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Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration.
Carsten Merkwirth, Paola Martinelli, Anne Korwitz, Michela Morbin, Hella S Brönneke

PLoS Genet· May 2013

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RPN-6 determines C. elegans longevity under proteotoxic stress conditions.
David Vilchez, Ianessa Morantte, Zheng Liu, Peter M Douglas, Carsten Merkwirth

Nature· September 2012

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Increased proteasome activity in human embryonic stem cells is regulated by PSMD11.
David Vilchez, Leah Boyer, Ianessa Morantte, Margaret Lutz, Carsten Merkwirth

Nature· September 2012

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The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells.
Olivier R Baris, Anke Klose, Jennifer E Kloepper, Daniela Weiland, Johannes F G Neuhaus, Carsten Merkwirth

Stem Cells· September 2011

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Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism.
Sabine D Jordan, Markus Krüger, Diana M Willmes, Nora Redemann, F Thomas Wunderlich, Carsten Merkwirth

Nat Cell Biol· April 2011

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Prohibitins and the functional compartmentalization of mitochondrial membranes.
Christof Osman, Carsten Merkwirth, Thomas Langer

J Cell Sci· November 2009

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SLP-2 is required for stress-induced mitochondrial hyperfusion.
Daniel Tondera, Stéphanie Grandemange, Alexis Jourdain, Mariusz Karbowski, Yves Mattenberger, Carsten Merkwirth

EMBO J· June 2009

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Prohibitin function within mitochondria: essential roles for cell proliferation and cristae morphogenesis.
Carsten Merkwirth, Thomas Langer

Biochim Biophys Acta· January 2009

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Mitofusin 2 builds a bridge between ER and mitochondria.
Carsten Merkwirth, Thomas Langer

Cell· December 2008

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Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria.
Carsten Merkwirth, Sascha Dargazanli, Takashi Tatsuta, Stefan Geimer, Beatrix Löwer

Genes Dev· February 2008

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Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD.
Nadine Hövelmeyer, F Thomas Wunderlich, Ramin Massoumi, Charlotte G Jakobsen, Jian Song, Carsten Merkwirth

J Exp Med· October 2007

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