Publications by authors named "Casey D Johnson"

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Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Casey D Johnson

Sci Rep· November 2023

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Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis.
Davide Povero, Milos Lazic, Christopher McBride, Geza Ambrus-Aikelin, Ryan Stansfield, Casey D Johnson

J Pharmacol Exp Ther· August 2023

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JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Casey D Johnson

Sci Rep· August 2023

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Feeding mice a diet high in oxidized linoleic acid metabolites does not alter liver oxylipin concentrations.
Nuanyi Liang, Marie Hennebelle, Susanne Gaul, Casey D Johnson, Zhichao Zhang

Prostaglandins Leukot Essent Fatty Acids· September 2021

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Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.
Susanne Gaul, Aleksandra Leszczynska, Fernando Alegre, Benedikt Kaufmann, Casey D Johnson

J Hepatol· January 2021

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MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury.
Carolina Jimenez Calvente, Hana Del Pilar, Masahiko Tameda, Casey D Johnson, Ariel E Feldstein

Mol Ther· February 2020

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ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.
Susanne Schuster-Gaul, Lukas Jonathan Geisler, Matthew D McGeough, Casey D Johnson, Anna Zagorska

JCI Insight· January 2020

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Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.
Carolina Jimenez Calvente, Masahiko Tameda, Casey D Johnson, Hana Del Pilar, Yun Chin Lin

J Clin Invest· July 2019

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NLR Family Pyrin Domain-Containing 3 Inflammasome Activation in Hepatic Stellate Cells Induces Liver Fibrosis in Mice.
Maria Eugenia Inzaugarat, Casey D Johnson, Theresa Maria Holtmann, Matthew D McGeough, Christian Trautwein

Hepatology· February 2019

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Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?
Domenico Tricò, Anna Di Sessa, Sonia Caprio, Naga Chalasani, Wanqing Liu, Casey D Johnson

Antioxid Redox Signal· January 2019

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Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis.
Igor Maricic, Idania Marrero, Akiko Eguchi, Ryota Nakamura, Casey D Johnson

J Immunol· November 2018

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Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice.
Christopher E Ramsden, Marie Hennebelle, Susanne Schuster, Gregory S Keyes, Casey D Johnson

Biochim Biophys Acta Mol Cell Biol Lipids· October 2018

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Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice.
Susanne Schuster, Casey D Johnson, Marie Hennebelle, Theresa Holtmann, Ameer Y Taha

J Lipid Res· September 2018

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Emricasan, a pan-caspase inhibitor, improves survival and portal hypertension in a murine model of common bile-duct ligation.
Akiko Eguchi, Yukinori Koyama, Alexander Wree, Casey D Johnson, Ryota Nakamura

J Mol Med (Berl)· June 2018

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NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice.
Alexander Wree, Matthew D McGeough, Maria Eugenia Inzaugarat, Akiko Eguchi, Susanne Schuster, Casey D Johnson

Hepatology· February 2018

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TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies.
Matthew D McGeough, Alexander Wree, Maria E Inzaugarat, Ariela Haimovich, Casey D Johnson

J Clin Invest· December 2017

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NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.
Auvro R Mridha, Alexander Wree, Avril A B Robertson, Matthew M Yeh, Casey D Johnson

J Hepatol· May 2017

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Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis.
Akiko Eguchi, Toru Yoshitomi, Milos Lazic, Casey D Johnson, Long Binh Vong

Nanomedicine (Lond)· July 2016

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Liver Bid suppression for treatment of fibrosis associated with non-alcoholic steatohepatitis.
Akiko Eguchi, Xavier De Mollerat Du Jeu, Casey D Johnson, Andronikou Nektaria, Ariel E Feldstein

J Hepatol· March 2016

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Lipid-induced hepatocyte-derived extracellular vesicles regulate hepatic stellate cell via microRNAs targeting PPAR-γ.
Davide Povero, Nadia Panera, Akiko Eguchi, Casey D Johnson, Bettina G Papouchado

Cell Mol Gastroenterol Hepatol· November 2015

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Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease.
Davide Povero, Akiko Eguchi, Hongying Li, Casey D Johnson, Bettina G Papouchado

PLoS One· July 2015

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Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice.
Milos Lazic, Akiko Eguchi, Michael P Berk, Davide Povero, Bettina Papouchado, Casey D Johnson

J Hepatol· July 2014

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NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice.
Alexander Wree, Akiko Eguchi, Matthew D McGeough, Carla A Pena, Casey D Johnson

Hepatology· March 2014

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