Publications by authors named "Cassandra M Modahl"

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Exceptional Visual-Opsin Coexpression and Phenotypic Diversity in Outer-Retinal Photoreceptors of Caenophidian Snakes.
Einat Hauzman, Silke Haverkamp, Juliana H Tashiro, Irene L Gügel, Natalia F Torello-Viera, Cassandra M Modahl

J Comp Neurol· October 2025

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Discerning specific thrombolytic activities and blood clot degradomes of diverse snake venoms with untargeted peptidomics.
Cara F Smith, Mamadou Alpha Baldé, Stephanie French, Cassandra M Modahl, Lilyrose Bahrabadi

J Thromb Haemost· July 2025

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Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease.
Stephanie French, Rachael Da Silva, Janet Storm, Christida E Wastika, India Cullen, Cassandra M Modahl

Parasit Vectors· January 2025

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Intraspecific venom variation in the medically important puff adder (Bitis arietans): Comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom.
Charlotte A Dawson, Keirah E Bartlett, Mark C Wilkinson, Stuart Ainsworth, Laura-Oana Albulescu, Cassandra M Modahl

PLoS Negl Trop Dis· October 2024

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Assessing Target Specificity of the Small Molecule Inhibitor MARIMASTAT to Snake Venom Toxins: A Novel Application of Thermal Proteome Profiling.
Cara F Smith, Cassandra M Modahl, David Ceja Galindo, Keira Y Larson, Sean P Maroney

Mol Cell Proteomics· June 2024

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Investigating Snake-Venom-Induced Dermonecrosis and Inflammation Using an Ex Vivo Human Skin Model.
Jaffer Alsolaiss, Gail Leeming, Rachael Da Silva, Nessrin Alomran, Nicholas R Casewell, Cassandra M Modahl

Toxins (Basel)· June 2024

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Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib.
Keirah E Bartlett, Steven R Hall, Sean A Rasmussen, Edouard Crittenden, Charlotte A Dawson, Cassandra M Modahl

Proc Natl Acad Sci U S A· May 2024

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Studying Venom Toxin Variation Using Accurate Masses from Liquid Chromatography-Mass Spectrometry Coupled with Bioinformatic Tools.
Luis L Alonso, Jory van Thiel, Julien Slagboom, Nathan Dunstan, Cassandra M Modahl

Toxins (Basel)· April 2024

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Distinct regulatory networks control toxin gene expression in elapid and viperid snakes.
Cassandra M Modahl, Summer Xia Han, Jory van Thiel, Candida Vaz, Nathan L Dunstan

BMC Genomics· February 2024

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Editorial: Experimental and computational aspects of bioactive proteins from animal venoms: an insight into pharmacological properties and drug discovery.
Michelle Khai Khun Yap, Cassandra M Modahl, Steven R Hall

Front Pharmacol· February 2024

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Niemann-Pick Type C2 Proteins in : Molecular Modelling and Prediction of Their Structure-Function Relationships.
Prathigna Jaishankar Thambi, Cassandra M Modahl, R Manjunatha Kini

Int J Mol Sci· January 2024

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Midgut transcriptomic responses to dengue and chikungunya viruses in the vectors Aedes albopictus and Aedes malayensis.
Cassandra M Modahl, Avisha Chowdhury, Dolyce H W Low, Menchie C Manuel, Dorothée Missé

Sci Rep· July 2023

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Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans ( spp.) and Brown Snakes ( spp.).
Jory van Thiel, Luis L Alonso, Julien Slagboom, Nathan Dunstan, Roel M Wouters, Cassandra M Modahl

Toxins (Basel)· January 2023

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Metabolic Processes Are Differentially Regulated During Wild-Type and Attenuated Dengue Virus Infection in Aedes aegypti.
Tanamas Siriphanitchakorn, Cassandra M Modahl, R Manjunatha Kini, Eng Eong Ooi, Milly M Choy

Am J Trop Med Hyg· January 2022

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High resolution proteomics of Aedes aegypti salivary glands infected with either dengue, Zika or chikungunya viruses identify new virus specific and broad antiviral factors.
Avisha Chowdhury, Cassandra M Modahl, Dorothée Missé, R Manjunatha Kini, Julien Pompon

Sci Rep· December 2021

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Integration of transcriptomic and proteomic approaches for snake venom profiling.
Cassandra M Modahl, Anthony J Saviola, Stephen P Mackessy

Expert Rev Proteomics· October 2021

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The RNA binding protein Quaking represses splicing of the Fibronectin EDA exon and downregulates the interferon response.
Kuo-Chieh Liao, Vanessa Chuo, W Samuel Fagg, Cassandra M Modahl, Steven Widen

Nucleic Acids Res· September 2021

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Exploring Toxin Evolution: Venom Protein Transcript Sequencing and Transcriptome-Guided High-Throughput Proteomics.
Cassandra M Modahl, Jordi Durban, Stephen P Mackessy

Methods Mol Biol· December 2020

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JNK pathway restricts DENV2, ZIKV and CHIKV infection by activating complement and apoptosis in mosquito salivary glands.
Avisha Chowdhury, Cassandra M Modahl, Siok Thing Tan, Benjamin Wong Wei Xiang, Dorothée Missé

PLoS Pathog· August 2020

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Interspecific and intraspecific venom enzymatic variation among cobras (Naja sp. and Ophiophagus hannah).
Cassandra M Modahl, Amir Roointan, Jessica Rogers, Katelyn Currier, Stephen P Mackessy

Comp Biochem Physiol C Toxicol Pharmacol· June 2020

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Cysteine-Rich Secretory Proteins (CRISPs) From Venomous Snakes: An Overview of the Functional Diversity in A Large and Underappreciated Superfamily.
Takashi Tadokoro, Cassandra M Modahl, Katsumi Maenaka, Narumi Aoki-Shioi

Toxins (Basel)· March 2020

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Omics Technologies for Profiling Toxin Diversity and Evolution in Snake Venom: Impacts on the Discovery of Therapeutic and Diagnostic Agents.
Cassandra M Modahl, Rajeev Kungur Brahma, Cho Yeow Koh, Narumi Shioi, R Manjunatha Kini

Annu Rev Anim Biosci· February 2020

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Transcriptome-facilitated proteomic characterization of rear-fanged snake venoms reveal abundant metalloproteinases with enhanced activity.
Cassandra M Modahl, Seth Frietze, Stephen P Mackessy

J Proteomics· September 2018

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Proteomic Deep Mining the Venom of the Red-Headed Krait, .
Alex Chapeaurouge, Andreza Silva, Paulo Carvalho, Ryan J R McCleary, Cassandra Marie Modahl

Toxins (Basel)· September 2018

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Adaptive evolution of distinct prey-specific toxin genes in rear-fanged snake venom.
Cassandra M Modahl, Mrinalini, Seth Frietze, Stephen P Mackessy

Proc Biol Sci· August 2018

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