Publications by authors named "Celine Desvignes"

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Immunoglobulin G Receptors (FcγR), in Addition to Target-Antigen and Neonatal Fc Receptor (FcRn), Influence Rituximab Pharmacokinetics.
David Ternant, Olivier Le Tilly, Guillaume Cartron, Céline Desvignes, Amina Bensalem

Clin Pharmacokinet· November 2025

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Quality Assessment of Therapeutic Drug Monitoring Assays of Therapeutic Antibodies Across Europe: An Update.
James Bluett, Merita Rumano, María José Martínez Becerra, Floris Loeff, Mehmet Itik, Céline Desvignes

Basic Clin Pharmacol Toxicol· November 2025

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Eculizumab dose tapering should take into account the nonlinearity of its pharmacokinetics.
Olivier Le Tilly, Philippe Gatault, Saida Semlali, Rebecca Sberro-Soussan, Christophe Passot, Céline Desvignes

Br J Clin Pharmacol· May 2024

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Confounding mitigation for the exposure-response relationship of bevacizumab in colorectal cancer patients.
Sarah Lobet, Morgane Caulet, Gilles Paintaud, Nicolas Azzopardi, Céline Desvignes

Br J Clin Pharmacol· April 2024

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A Fab of trastuzumab to treat HER2 overexpressing breast cancer brain metastases.
Eurydice Angeli, Justine Paris, Olivier Le Tilly, Céline Desvignes, Guillaume Gapihan

Exp Hematol Oncol· April 2024

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Efficacy and safety of intravenous bevacizumab on severe bleeding associated with hemorrhagic hereditary telangiectasia: A national, randomized multicenter trial.
Sophie Dupuis-Girod, Sophie Rivière, Christian Lavigne, Anne-Emmanuelle Fargeton, Brigitte Gilbert-Dussardier, Céline Desvignes

J Intern Med· December 2023

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Relationship Between Cetuximab Target-Mediated Pharmacokinetics and Progression-Free Survival in Metastatic Colorectal Cancer Patients.
Sarah Lobet, Gilles Paintaud, Nicolas Azzopardi, Christophe Passot, Morgane Caulet, Céline Desvignes

Clin Pharmacokinet· September 2023

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The Influence of Underlying Disease on Rituximab Pharmacokinetics May be Explained by Target-Mediated Drug Disposition.
Amina Bensalem, Guillaume Cartron, Ulrich Specks, Denis Mulleman, Emmanuel Gyan, Celine Desvignes

Clin Pharmacokinet· March 2022

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Infliximab Efficacy May Be Linked to Full TNF-α Blockade in Peripheral Compartment-A Double Central-Peripheral Target-Mediated Drug Disposition (TMDD) Model.
David Ternant, Olivier Le Tilly, Laurence Picon, Driffa Moussata, Christophe Passot, Céline Desvignes

Pharmaceutics· November 2021

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Antigen Mass May Influence Trastuzumab Concentrations in Cerebrospinal Fluid After Intrathecal Administration.
Olivier Le Tilly, Nicolas Azzopardi, Claire Bonneau, Céline Desvignes, Florence Oberkampf

Clin Pharmacol Ther· July 2021

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Panitumumab and cetuximab affect differently miRNA expression in colorectal cancer cells.
Romain Chautard, Laetitia Corset, Sajida Ibrahim, Céline Desvignes, Gilles Paintaud

Biomark Med· June 2021

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Association of IgG1 Antibody Clearance with FcγRIIA Polymorphism and Platelet Count in Infliximab-Treated Patients.
Gilles Thibault, Gilles Paintaud, Hsueh Cheng Sung, Laurie Lajoie, Edouard Louis, Celine Desvignes

Int J Mol Sci· June 2021

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A robust enzyme-linked immunosorbent assay to measure serum ramucirumab concentrations.
Céline Desvignes, David Ternant, Thierry Lecomte, Astrid Lièvre, Marc Ohresser

Bioanalysis· April 2021

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Methotrexate effect on immunogenicity and long-term maintenance of adalimumab in axial spondyloarthritis: a multicentric randomised trial.
Emilie Ducourau, Theo Rispens, Marine Samain, Emmanuelle Dernis, Fabienne Le Guilchard, Céline Desvignes

RMD Open· January 2020

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A successful compartmental approach for the treatment of breast cancer brain metastases.
Thuy T Nguyen, Eurydice Angeli, François Darrouzain, Quang T Nguyen, Céline Desvignes

Cancer Chemother Pharmacol· March 2019

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Model-Based Therapeutic Drug Monitoring of Infliximab Using a Single Serum Trough Concentration.
David Ternant, Christophe Passot, Alexandre Aubourg, Philippe Goupille, Céline Desvignes

Clin Pharmacokinet· September 2018

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Phase I feasibility study for intrathecal administration of trastuzumab in patients with HER2 positive breast carcinomatous meningitis.
Claire Bonneau, Gilles Paintaud, Olivier Trédan, Coraline Dubot, Céline Desvignes

Eur J Cancer· May 2018

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Development and validation of an ELISA to study panitumumab pharmacokinetics.
Céline Desvignes, Christophe Passot, David Ternant, Morgane Caulet, Caroline Guérineau

Bioanalysis· February 2018

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Antigenic burden and serum IgG concentrations influence rituximab pharmacokinetics in rheumatoid arthritis patients.
Bertrand Lioger, Soujanya Ratna Edupuganti, Denis Mulleman, Christophe Passot, Céline Desvignes

Br J Clin Pharmacol· August 2017

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Immunoassays for Measuring Serum Concentrations of Monoclonal Antibodies and Anti-biopharmaceutical Antibodies in Patients.
François Darrouzain, Sumin Bian, Céline Desvignes, Céline Bris, Hervé Watier

Ther Drug Monit· August 2017

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Development and validation of an enzyme-linked immunosorbent assay to measure free eculizumab concentration in serum.
Christophe Passot, Céline Desvignes, David Ternant, Theodora Bejan-Angoulvant, Anne-Claire Duveau

Bioanalysis· August 2017

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Crucial Role for Immune Complexes but Not FcRn in Immunization against Anti-TNF-α Antibodies after a Single Injection in Mice.
Christophe Arnoult, Guillaume Brachet, Diana Cadena Castaneda, Nicolas Azzopardi, Christophe Passot, Celine Desvignes

J Immunol· July 2017

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BRAF inhibitor discontinuation and rechallenge in advanced melanoma patients with a complete initial treatment response.
Céline Desvignes, Henry Abi Rached, Carole Templier, Elodie Drumez, Pauline Lepesant

Melanoma Res· June 2017

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Efficacy of a rituximab regimen based on B cell depletion in thrombotic thrombocytopenic purpura with suboptimal response to standard treatment: Results of a phase II, multicenter noncomparative study.
Ygal Benhamou, Gilles Paintaud, Elie Azoulay, Pascale Poullin, Lionel Galicier, Céline Desvignes

Am J Hematol· December 2016

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Pharmacokinetics of adalimumab in Crohn's disease.
David Ternant, Konstantinos Karmiris, Severine Vermeire, Céline Desvignes, Nicolas Azzopardi

Eur J Clin Pharmacol· September 2015

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