Publications by authors named "Ceri Oldreive"

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Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma.
Nicholas Davies, Tegan Francis, Ceri Oldreive, Maria Azam, Jordan Wilson

Haematologica· December 2024

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SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response.
Philip Bland, Harry Saville, Patty T Wai, Lucinda Curnow, Gareth Muirhead, Ceri Oldreive

Nat Genet· August 2023

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TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target.
Emma Kennedy, Eve Coulter, Emma Halliwell, Nuria Profitos-Peleja, Elisabeth Walsby, Ceri Oldreive

Blood· June 2021

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Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.
Marwan Kwok, Ceri Oldreive, Andy C Rawstron, Anshita Goel, Grigorios Papatzikas

Blood· February 2020

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variant status in hematological malignancies - a potential therapeutic target?
Ceri E Oldreive, Philip J Byrd, Grant S Stewart, Alexander J Taylor, Sana Farhat

Leuk Lymphoma· July 2019

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A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma.
Guy Pratt, Christina Yap, Ceri Oldreive, Daniel Slade, Rebecca Bishop

Br J Haematol· August 2018

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USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status.
Angelo Agathanggelou, Edward Smith, Nicholas J Davies, Marwan Kwok, Anastasia Zlatanou, Ceri E Oldreive

Blood· July 2017

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Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts.
Nicholas J Davies, Marwan Kwok, Clive Gould, Ceri E Oldreive, Jingwen Mao

Oncotarget· July 2017

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NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma.
Helen M Parry, Tom Stevens, Ceri Oldreive, Bassier Zadran, Tina McSkeane

Oncotarget· October 2016

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Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.
Ferran Nadeu, Julio Delgado, Cristina Royo, Tycho Baumann, Tatjana Stankovic, Ceri Oldreive

Blood· April 2016

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ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.
Marwan Kwok, Nicholas Davies, Angelo Agathanggelou, Edward Smith, Ceri Oldreive

Blood· February 2016

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T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice.
Ceri E Oldreive, Anna Skowronska, Nicholas J Davies, Helen Parry, Angelo Agathanggelou

Dis Model Mech· November 2015

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Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants.
Angelo Agathanggelou, Victoria J Weston, Tracey Perry, Nicholas J Davies, Anna Skowronska, Ceri E Oldreive

Haematologica· August 2015

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Biallelic ATM inactivation significantly reduces survival in patients treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 trial.
Anna Skowronska, Anton Parker, Gulshanara Ahmed, Ceri Oldreive, Zadie Davis

J Clin Oncol· December 2012

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Effects of nitric oxide on the survival and neuritogenesis of cerebellar Purkinje neurons.
Ceri E Oldreive, Steven Gaynor, Gayle Helane Doherty

J Mol Neurosci· February 2012

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The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.
Victoria J Weston, Ceri E Oldreive, Anna Skowronska, David G Oscier, Guy Pratt

Blood· November 2010

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Effects of tumour necrosis factor-alpha on developing cerebellar granule and Purkinje neurons in vitro.
Ceri E Oldreive, Gayle H Doherty

J Mol Neurosci· September 2010

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The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.
Grant S Stewart, Stephanie Panier, Kelly Townsend, Abdallah K Al-Hakim, Nadine K Kolas, Ceri Oldreive

Cell· February 2009

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Developmental changes in the response of murine cerebellar granule cells to nitric oxide.
Ceri E Oldreive, Steven Gaynor, Gayle H Doherty

Neurochem Int· June 2008

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Neurotrophic effects of leptin on cerebellar Purkinje but not granule neurons in vitro.
Ceri E Oldreive, Jenni Harvey, Gayle H Doherty

Neurosci Lett· June 2008

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Neurotoxic effects of homocysteine on cerebellar Purkinje neurons in vitro.
Ceri E Oldreive, Gayle H Doherty

Neurosci Lett· February 2007

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Embryonic cerebellar granule cells are resistant to necrosis induced by homocysteine.
Nicola S L Foister, Ceri E Oldreive, John B Mackie, Gayle H Doherty

Brain Res Dev Brain Res· November 2005

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Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/- mice.
Andrew Devitt, Kate G Parker, Carol Anne Ogden, Ceri Oldreive, Michael F Clay

J Cell Biol· December 2004

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