Publications by authors named "Ceri Wiggins"

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Hit screening with multivariate robust outlier detection.
Hui Sun Leong, Tianhui Zhang, Adam Corrigan, Alessia Serrano, Ulrike Künzel, Ceri Wiggins

PLoS One· September 2024

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An aptamer-mediated base editing platform for simultaneous knockin and multiple gene knockout for allogeneic CAR-T cells generation.
Immacolata Porreca, Robert Blassberg, Jennifer Harbottle, Bronwyn Joubert, Olga Mielczarek, Ceri M Wiggins

Mol Ther· August 2024

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Highly scalable arrayed CRISPR mediated gene silencing in primary lung small airway epithelial cells.
Anna Dickson, Niamh Mullooly, Alessia Serrano, Leire Escudero-Ibarz, Ceri Wiggins

SLAS Discov· March 2023

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Development and Characterization of a Modular CRISPR and RNA Aptamer Mediated Base Editing System.
Juan Carlos Collantes, Victor M Tan, Huiting Xu, Melany Ruiz-Urigüen, Amer Alasadi, Ceri M Wiggins

CRISPR J· February 2021

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A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds.
Claire J Cairney, Lauren S Godwin, Alan E Bilsland, Sharon Burns, Katrina H Stevenson, Ceri M Wiggins

PLoS Genet· August 2017

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Pre-clinical use of isogenic cell lines and tumours in vitro and in vivo for predictive biomarker discovery; impact of KRAS and PI3KCA mutation status on MEK inhibitor activity is model dependent.
Emma J Haagensen, Huw D Thomas, Clare Mudd, Elpida Tsonou, Ceri M Wiggins

Eur J Cancer· March 2016

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BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation.
Ceri M Wiggins, Peter Tsvetkov, Mark Johnson, Claire L Joyce, Christopher A Lamb

J Cell Sci· March 2011

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Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM.
Ceri M Wiggins, Mark Johnson, Simon J Cook

Cell Signal· May 2010

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Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics.
Annette S Gillings, Kathryn Balmanno, Ceri M Wiggins, Mark Johnson, Simon J Cook

FEBS J· November 2009

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c-Cbl is not required for ERK1/2-dependent degradation of BimEL.
Ceri M Wiggins, Hamid Band, Simon J Cook

Cell Signal· December 2007

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Bim and the pro-survival Bcl-2 proteins: opposites attract, ERK repels.
Katherine E Ewings, Ceri M Wiggins, Simon J Cook

Cell Cycle· September 2007

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ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL.
Katherine E Ewings, Kathryn Hadfield-Moorhouse, Ceri M Wiggins, Julie A Wickenden, Kathryn Balmanno

EMBO J· June 2007

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