Publications by authors named "Cesar A Santa-Maria"

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Machine Learning-Based Prediction of Distant Recurrence Risk and Ribociclib Treatment Effect in HR+/HER2- Early Breast Cancer Using Real-World and NATALEE Data.
Frederick M Howard, Peter A Fasching, Cesar A Santa-Maria, Elgene Lim, Joseph A Sparano

Clin Cancer Res· November 2025

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NCCN Guidelines® Insights: Breast Cancer, Version 5.2025.
William J Gradishar, Meena S Moran, Jame Abraham, Vandana Abramson, Rebecca Aft, Cesar A Santa-Maria

J Natl Compr Canc Netw· November 2025

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Prognostic value of visually and computationally-assessed tumor-infiltrating lymphocytes in early-stage triple-negative breast cancer (TBCRC-030).
Guilherme Nader-Marta, Xiangying Chu, Satabhisa Mukhopadhyay, Vandana G Abramson, Adam Brufsky, Cesar Augusto Santa-Maria

J Natl Cancer Inst· October 2025

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Bi-level graph learning unveils prognosis-relevant tumor microenvironment patterns in breast multiplexed digital pathology.
Zhenzhen Wang, Cesar A Santa-Maria, Aleksander S Popel, Jeremias Sulam

Patterns (N Y)· March 2025

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Spatial Architecture of Single-Cell and Vasculature in Tumor Microenvironment Predicts Clinical Outcomes in Triple-Negative Breast Cancer.
Haoyang Mi, Ravi Varadhan, Ashley M Cimino-Mathews, Leisha A Emens, Cesar A Santa-Maria

Mod Pathol· February 2025

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Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade.
Theinmozhi Arulraj, Hanwen Wang, Atul Deshpande, Ravi Varadhan, Leisha A Emens, Cesar A Santa-Maria

Proc Natl Acad Sci U S A· November 2024

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Bi-level Graph Learning Unveils Prognosis-Relevant Tumor Microenvironment Patterns in Breast Multiplexed Digital Pathology.
Zhenzhen Wang, Cesar A Santa-Maria, Aleksander S Popel, Jeremias Sulam

bioRxiv· October 2024

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OptimICE-RD: sacituzumab govitecan + pembrolizumab vs pembrolizumab (± capecitabine) for residual triple-negative breast cancer.
Sara M Tolaney, Angela DeMichele, Toshimi Takano, Hope S Rugo, Charles Perou, Cesar Augusto Santa-Maria

Future Oncol· October 2024

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Hypoxia induces ROS-resistant memory upon reoxygenation in vivo promoting metastasis in part via MUC1-C.
Inês Godet, Harsh H Oza, Yi Shi, Natalie S Joe, Alyssa G Weinstein, Cesar A Santa-Maria

Nat Commun· September 2024

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Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade.
Theinmozhi Arulraj, Hanwen Wang, Atul Deshpande, Ravi Varadhan, Leisha A Emens, Cesar A Santa-Maria

bioRxiv· May 2024

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Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer.
Elizabeth C Wescott, Xiaopeng Sun, Paula Gonzalez-Ericsson, Ann Hanna, Brandie C Taylor, Cesar A Santa-Maria

Cancer Res Commun· April 2024

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NKG2A Is a Therapeutic Vulnerability in Immunotherapy Resistant MHC-I Heterogeneous Triple-Negative Breast Cancer.
Brandie C Taylor, Xiaopeng Sun, Paula I Gonzalez-Ericsson, Violeta Sanchez, Melinda E Sanders, Cesar A Santa-Maria

Cancer Discov· February 2024

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Atezolizumab in Combination With Carboplatin and Survival Outcomes in Patients With Metastatic Triple-Negative Breast Cancer: The TBCRC 043 Phase 2 Randomized Clinical Trial.
Brian D Lehmann, Vandana G Abramson, E Claire Dees, Payal D Shah, Tarah J Ballinger, Cesar A Santa-Maria

JAMA Oncol· February 2024

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Spatial and Compositional Biomarkers in Tumor Microenvironment Predicts Clinical Outcomes in Triple-Negative Breast Cancer.
Haoyang Mi, Ravi Varadhan, Ashley M Cimino-Mathews, Leisha A Emens, Cesar A Santa-Maria

bioRxiv· December 2023

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Feasibility of Symptom Monitoring During the First Year of Endocrine Therapy for Early Breast Cancer Using Patient-Reported Outcomes Collected via Smartphone App.
Karen Lisa Smith, Hua-Ling Tsai, David Lim, Chenguang Wang, Raquel Nunes, Cesar A Santa-Maria

JCO Oncol Pract· November 2023

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The PD-1- and LAG-3-targeting bispecific molecule tebotelimab in solid tumors and hematologic cancers: a phase 1 trial.
Jason J Luke, Manish R Patel, George R Blumenschein, Erika Hamilton, Bartosz Chmielowski, Cesar A Santa-Maria

Nat Med· November 2023

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Exceptional responses to PARP inhibitors in patients with metastatic breast cancer in oncologic crisis.
Joyce M Cheng, Jenna Canzoniero, Seoho Lee, Sudeep Soni, Neha Mangini, Cesar A Santa-Maria

Breast Cancer Res Treat· June 2023

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A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition.
Theinmozhi Arulraj, Hanwen Wang, Leisha A Emens, Cesar A Santa-Maria, Aleksander S Popel

Sci Adv· June 2023

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Optimizing and Refining Immunotherapy in Breast Cancer.
Cesar A Santa-Maria

JCO Oncol Pract· April 2023

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A Phase II Single-arm Study of Palbociclib in Patients With HER2-positive Breast Cancer With Brain Metastases and Analysis of ctDNA in Patients With Active Brain Metastases.
Ami N Shah, Cesar A Santa-Maria, Dhruvika Mukhija, Nikita Shah, Anthony K Kang

Clin Breast Cancer· April 2023

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Antibody-Drug Conjugates in Breast Cancer: Searching for Magic Bullets.
Cesar A Santa-Maria, Antonio C Wolff

J Clin Oncol· February 2023

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A randomized phase 2 study of neoadjuvant carboplatin and paclitaxel with or without atezolizumab in triple negative breast cancer (TNBC) - NCI 10013.
Foluso O Ademuyiwa, Feng Gao, Cherease R Street, Ina Chen, Donald W Northfelt, Cesar A Santa-Maria

NPJ Breast Cancer· December 2022

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The tumor microenvironment and triple-negative breast cancer aggressiveness: shedding light on mechanisms and targeting.
Natsuki Furukawa, Vered Stearns, Cesar A Santa-Maria, Aleksander S Popel

Expert Opin Ther Targets· December 2022

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Author Correction: Neoadjuvant study of niraparib in patients with HER2-negative, BRCA-mutated, resectable breast cancer.
Laura M Spring, Hyo Han, Minetta C Liu, Erika Hamilton, Hanna Irie, Cesar A Santa-Maria

Nat Cancer· September 2022

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Call for action: expanding global access to hereditary cancer genetic testing.
Brittany Bychkovsky, Huma Q Rana, Foluso Ademuyiwa, Jennifer Plichta, Karen Anderson, Cesar A Santa-Maria

Lancet Oncol· September 2022

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