Publications by authors named "Chad Cowan"

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Universal protection of allogeneic T-cell therapies from natural killer cells via CD300a agonism.
Shu-Qi Zhang, Faith Thomas, Justin Fang, Kathryn Austgen, Chad Cowan

Blood Adv· January 2025

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Chromatin regulator SMARCAL1 modulates cellular lipid metabolism.
Taylor Hanta Nagai, Chrissy Hartigan, Taiji Mizoguchi, Haojie Yu, Amy Deik, Chad A Cowan

Commun Biol· December 2023

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Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis.
Marlies P Rossmann, Karen Hoi, Victoria Chan, Brian J Abraham, Song Yang, Chad A Cowan

Science· May 2021

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Fattening chips: hypertrophy, feeding, and fasting of human white adipocytes .
Benjamin D Pope, Curtis R Warren, Madeleine O Dahl, Christina V Pizza, Douglas E Henze, Chad A Cowan

Lab Chip· November 2020

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A coagulation defect arising from heterozygous premature termination of tissue factor.
Sol Schulman, Emale El-Darzi, Mary Hc Florido, Max Friesen, Glenn Merrill-Skoloff, Chad A Cowan

J Clin Invest· October 2020

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Interactomics Analyses of Wild-Type and Mutant A1CF Reveal Diverged Functions in Regulating Cellular Lipid Metabolism.
Yu-Xin Xu, Caroline Stanclift, Taylor Hanta Nagai, Haojie Yu, Shamsudheen Karuthedath Vellarikkal, Chad Cowan

J Proteome Res· October 2020

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Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells.
Filip Roudnicky, Jitao David Zhang, Bo Kyoung Kim, Nikhil J Pandya, Yanjun Lan, Chad A Cowan

Proc Natl Acad Sci U S A· August 2020

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Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis.
Takafumi Toyohara, Filip Roudnicky, Mary H C Florido, Toshiaki Nakano, Haojie Yu, Chad A Cowan

Cell Stem Cell· July 2020

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Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program.
Kanika Kanchan, Kruthika Iyer, Lisa R Yanek, Ivan Carcamo-Orive, Margaret A Taub, Chad Cowan

Stem Cell Res· July 2020

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Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis.
Takafumi Toyohara, Filip Roudnicky, Mary H C Florido, Toshiaki Nakano, Haojie Yu, Chad A Cowan

Cell Stem Cell· July 2020

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Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.
Siwei Zhang, Hanwen Zhang, Yifan Zhou, Min Qiao, Siming Zhao, Chad A Cowan

Science· July 2020

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Mitoregulin Controls β-Oxidation in Human and Mouse Adipocytes.
Max Friesen, Curtis R Warren, Haojie Yu, Takafumi Toyohara, Qiurong Ding, Chad A Cowan

Stem Cell Reports· April 2020

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Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance.
Filip Roudnicky, Bo Kyoung Kim, Yanjun Lan, Roland Schmucki, Verena Küppers, Chad A Cowan

Sci Rep· March 2020

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Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes.
Zhifen Chen, Haojie Yu, Xu Shi, Curtis R Warren, Luca A Lotta, Chad A Cowan

Circ Res· January 2020

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Modeling the Effects of Severe Metabolic Disease by Genome Editing of hPSC-Derived Endothelial Cells Reveals an Inflammatory Phenotype.
Filip Roudnicky, Yanjun Lan, Max Friesen, Gregor Dernick, Jitao David Zhang, Chad A Cowan

Int J Mol Sci· December 2019

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GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis.
Haojie Yu, Antoine Rimbert, Alice E Palmer, Takafumi Toyohara, Yulei Xia, Chad A Cowan

Cell· November 2019

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Adipocyte Metabolism and Insulin Signaling Perturbations: Insights from Genetics.
Max Friesen, Chad A Cowan

Trends Endocrinol Metab· June 2019

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Generation of hypoimmunogenic human pluripotent stem cells.
Xiao Han, Mengning Wang, Songwei Duan, Paul J Franco, Jennifer Hyoje-Ryu Kenty, Chad A Cowan

Proc Natl Acad Sci U S A· May 2019

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Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.
Jon Odorico, James Markmann, Douglas Melton, Julia Greenstein, Albert Hwa, Chad Cowan

Transplantation· August 2018

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An hPSC-Derived Tissue-Resident Macrophage Model Reveals Differential Responses of Macrophages to ZIKV and DENV Infection.
Jianshe Lang, Yichen Cheng, Alyssa Rolfe, Christy Hammack, Daniel Vera, Chad Cowan

Stem Cell Reports· August 2018

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Humanity in a Dish: Population Genetics with iPSCs.
Curtis R Warren, Chad A Cowan

Trends Cell Biol· January 2018

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FPLD2 LMNA mutation R482W dysregulates iPSC-derived adipocyte function and lipid metabolism.
Max Friesen, Chad A Cowan

Biochem Biophys Res Commun· January 2018

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Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol.
Yu-Xin Xu, Valeska Redon, Haojie Yu, William Querbes, James Pirruccello, Chad Cowan

Atherosclerosis· January 2018

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Exome-wide association study of plasma lipids in >300,000 individuals.
Dajiang J Liu, Gina M Peloso, Haojie Yu, Adam S Butterworth, Xiao Wang, Chad A Cowan

Nat Genet· December 2017

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Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci.
Marc P Forrest, Hanwen Zhang, Winton Moy, Heather McGowan, Catherine Leites, Chad A Cowan

Cell Stem Cell· September 2017

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