Publications by authors named "Chad Creighton"

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Genomic and Epigenomic Signatures Can Distinguish Aggressive Chromophobe Renal Cell Carcinoma from Indolent Renal Oncocytic Tumors in Clinical-grade Samples.
Roberto Ruiz-Cordero, Qi Wang, Gayatri Kumar, Mahmut Akgul, Chad J Creighton

Eur Urol Oncol· December 2025

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Targeting FZD6 creates therapeutically actionable vulnerabilities for advanced prostate cancer.
Yongtao Li, Zhicheng Zhou, Yiqun Zhang, Deyong Jia, Ding Wang, Chad J Creighton

Oncogene· December 2025

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Osimertinib activates a TGFβ2-dependent secretory program that drives lung adenocarcinoma progression.
Madhurima Ghosh, Chao Wu, Abhishek Kumar, Monique B Nilsson, John V Heymach, Chad J Creighton

J Clin Invest· December 2025

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UALCAN Mobile, an app for cancer proteogenomic data analysis.
David Rubey, Darshan S Chandrashekar, Ahmedur Rahman Shovon, Gopi Chand Puli, Santhosh Kumar Karthikeyan, Chad J Creighton

Res Sq· November 2025

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UALCAN Mobile, an app for cancer proteogenomic data analysis.
David Rubey, Darshan Shimoga Chandrashekar, Ahmedur Rahman Shovon, Gopi Chand Puli, Santhosh Kumar Karthikeyan, Chad J Creighton

bioRxiv· September 2025

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Rat somatic genome editing enables ER+ breast cancer modeling.
Wen Bu, Tobie Lee, Meenakshi Anurag, Yunfeng Ding, Ruixin Xu, Chad J Creighton

bioRxiv· September 2025

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Germline structural variations involving the pediatric brain tumor transcriptome include disease-relevant and ancestry-related genes.
Fengju Chen, Yiqun Zhang, Luis F Paulin, Fritz J Sedlazeck, Chad J Creighton

Acta Neuropathol Commun· August 2025

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Dichotomous roles of ACBD3 in NSCLC growth and metastasis.
Xiaochao Tan, Chao Wu, Priyam Banerjee, Shike Wang, Derrick L Cardin, Chad J Creighton

Oncogene· July 2025

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Pan-cancer, multi-omic correlates of survival transcending tumor lineage across 11,019 patients reveal targets and pathways.
Yiqun Zhang, Fengju Chen, Chad J Creighton

NPJ Precis Oncol· July 2025

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An Overview of Analytical Approaches to Cancer Proteogenomics.
Chad J Creighton

Methods Mol Biol· June 2025

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Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load.
Vasanthi Avadhanula, Chad J Creighton, Laura Ferlic-Stark, Divya Nagaraj, Yiqun Zhang

PLoS One· May 2025

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Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors.
Fengju Chen, Yiqun Zhang, Wei Li, Fritz J Sedlazeck, Lanlan Shen, Chad J Creighton

Nat Commun· May 2025

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MammOnc-DB, an integrative breast cancer data analysis platform for target discovery.
Santhosh Kumar Karthikeyan, Darshan S Chandrashekar, Snigdha Sahai, Sadeep Shrestha, Ritu Aneja, Chad J Creighton

NPJ Breast Cancer· April 2025

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Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway.
Jun Hyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Kuldeep S Attri, Chad J Creighton

Cell Rep Med· February 2025

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MAGE-A4 induces non-small cell lung cancer and tumor-promoting plasma cell accumulation.
Dominique Armstrong, Cheng-Yen Chang, Monica J Hong, Linda Green, Yichao Shen, Chad J Creighton

Sci Adv· February 2025

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Noncanonical Wnt/Ror2 Signaling Regulates Basal Cell Fidelity and Branching Morphogenesis in the Mammary Gland.
Hongjiang Si, Erika Mendoza Mendoza, Madelyn Esquivel, Chad J Creighton, Jianming Xu

bioRxiv· February 2025

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DNA methylation profiling at base-pair resolution reveals unique epigenetic features of early-onset colorectal cancer in underrepresented populations.
Jason Sheng Li, Karen Riggins, Li Yang, Chaorong Chen, Patricia Castro, Chad J Creighton

Clin Epigenetics· January 2025

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Inflammation-induced epigenetic imprinting regulates intestinal stem cells.
Dongchang Zhao, Visweswaran Ravikumar, Tyler J Leach, Daniel Kraushaar, Emma Lauder, Chad J Creighton

Cell Stem Cell· October 2024

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Mitochondrial reprogramming by activating OXPHOS via glutamine metabolism in African American patients with bladder cancer.
Karthik Reddy Kami Reddy, Danthasinghe Waduge Badrajee Piyarathna, Jun Hyoung Park, Vasanta Putluri, Chandra Sekhar Amara, Chad J Creighton

JCI Insight· September 2024

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MammOnc-DB, an integrative breast cancer data analysis platform for target discovery.
Sooryanarayana Varambally, Santhosh Kumar Karthikeyan, Darshan Chandrashekar, Snigdha Sahai, Sadeep Shrestha, Chad Creighton

Res Sq· September 2024

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Author Correction: TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.
Xiaohua Su, Deepavali Chakravarti, Min Soon Cho, Lingzhi Liu, Young Jin Gi, Chad J Creighton

Nature· August 2024

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The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival.
Fengju Chen, Yiqun Zhang, Lanlan Shen, Chad J Creighton

Nat Commun· August 2024

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MAGE-A4-Responsive Plasma Cells Promote Non-Small Cell Lung Cancer.
Dominique Armstrong, Cheng-Yen Chang, Monica J Hong, Linda Green, William Hudson, Chad J Creighton

bioRxiv· July 2024

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An essential gene signature of breast cancer metastasis reveals targetable pathways.
Yiqun Zhang, Fengju Chen, Marija Balic, Chad J Creighton

Breast Cancer Res· June 2024

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Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology.
Chandrashekhar Madasu, Zian Liao, Sydney E Parks, Kiran L Sharma, Kurt M Bohren, Chad J Creighton

Proc Natl Acad Sci U S A· May 2024

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