Publications by authors named "Chad E Stephens"

Claim this Profile
I
Identification of diphenyl furan derivatives via high throughput and computational studies as ArgA inhibitors of Mycobacterium tuberculosis.
Harleen Khurana, Mitul Srivastava, Deepika Chaudhary, Tannu Priya Gosain, Raniki Kumari, Chad E Stephens

Int J Biol Macromol· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model.
Sabine Depauw, Mélanie Lambert, Samy Jambon, Ananya Paul, Paul Peixoto, Chad E Stephens

J Med Chem· February 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
G-quadruplex-binding small molecules ameliorate FTD/ALS pathology and .
Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Chad E Stephens

EMBO Mol Med· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of infection.
Cristiane França da Silva, Denise da Gama Jaén Batista, Julianna Siciliano de Araújo, Edézio Ferreira Cunha-Junior, Chad E Stephens

Drug Des Devel Ther· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antiprion Activity of DB772 and Related Monothiophene- and Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture System.
Kelcey D Dinkel, James B Stanton, David W Boykin, Chad E Stephens, Sally A Madsen-Bouterse

Antimicrob Agents Chemother· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts.
Isabel Hostettler, Joachim Müller, Chad E Stephens, Richard Haynes, Andrew Hemphill

Int J Parasitol Drugs Drug Resist· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines.
Manoj Munde, Shuo Wang, Arvind Kumar, Chad E Stephens, Abdelbasset A Farahat

Nucleic Acids Res· January 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CYP1A1 and CYP1B1-mediated biotransformation of the antitrypanosomal methamidoxime prodrug DB844 forms novel metabolites through intramolecular rearrangement.
Wujian Ju, Sihyung Yang, John H Ansede, Chad E Stephens, Arlene S Bridges

J Pharm Sci· January 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro and in vivo activities of dicationic diguanidino compounds against Echinococcus multilocularis metacestodes.
Tatiana Küster, Nadja Kriegel, David W Boykin, Chad E Stephens, Andrew Hemphill

Antimicrob Agents Chemother· August 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines.
Raja Nhili, Paul Peixoto, Sabine Depauw, Sébastien Flajollet, Xavier Dezitter, Chad E Stephens

Nucleic Acids Res· January 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice.
Michelle Schorer, Karim Debache, Fabienne Barna, Thierry Monney, Joachim Müller, Chad E Stephens

Int J Parasitol Drugs Drug Resist· December 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies.
Xiaohua Zhu, Qiang Liu, Sihyung Yang, Toufan Parman, Carol E Green, Chad E Stephens

Antimicrob Agents Chemother· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The adaptive potential of a survival artist: characterization of the in vitro interactions of Toxoplasma gondii tachyzoites with di-cationic compounds in human fibroblast cell cultures.
Christian Kropf, Karim Debache, Christoph Rampa, Fabienne Barna, Michelle Schorer, Chad E Stephens

Parasitology· February 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Combined treatment of heterocyclic analogues and benznidazole upon Trypanosoma cruzi in vivo.
Denise da Gama Jaén Batista, Marcos Meuser Batista, Gabriel Melo de Oliveira, Constança Carvalho Britto, Ana Carolina Mondaine Rodrigues, Chad E Stephens

PLoS One· December 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The efficacy of novel arylimidamides against Trypanosoma cruzi in vitro.
Cristiane França DA Silva, Anissa Daliry, Patrícia Bernardino DA Silva, Senol Akay, Moloy Banerjee, Chad E Stephens

Parasitology· December 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro efficacy of dicationic compounds and mefloquine enantiomers against Echinococcus multilocularis metacestodes.
Britta Stadelmann, Tatiana Küster, Sabrina Scholl, Fabienne Barna, Christian Kropf, Chad E Stephens

Antimicrob Agents Chemother· October 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Experimental treatment of Neospora caninum-infected mice with the arylimidamide DB750 and the thiazolide nitazoxanide.
Karim Debache, Christophe Guionaud, Christian Kropf, David Boykin, Chad E Stephens

Exp Parasitol· October 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi.
Cristiane França Da Silva, Angela Junqueira, Marli Maria Lima, Alvaro José Romanha, Policarpo Ademar Sales Junior, Chad E Stephens

J Antimicrob Chemother· June 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site.
Manoj Munde, Arvind Kumar, Raja Nhili, Sabine Depauw, Marie-Hélène David-Cordonnier, Chad E Stephens

J Mol Biol· October 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment.
Denise da Gama Jaén Batista, Marcos Meuser Batista, Gabriel Melo de Oliveira, Patrícia Borges do Amaral, Joseli Lannes-Vieira, Chad E Stephens

Antimicrob Agents Chemother· July 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel arylimidamides for treatment of visceral leishmaniasis.
Michael Zhuo Wang, Xiaohua Zhu, Anuradha Srivastava, Qiang Liu, J Mark Sweat, Chad E Stephens

Antimicrob Agents Chemother· June 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi.
Kirsten Gillingwater, Arvind Kumar, Mohamed A Ismail, Reem K Arafa, Chad E Stephens

Vet Parasitol· May 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Trypanosoma cruzi: activity of heterocyclic cationic molecules in vitro.
Michele Gabriele de Oliveira Pacheco, Cristiane França da Silva, Elen Mello de Souza, Marcos Meuser Batista, Patrícia Bernardino da Silva, Chad E Stephens

Exp Parasitol· September 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Large, sequence-dependent effects on DNA conformation by minor groove binding compounds.
Denise S Tevis, Arvind Kumar, Chad E Stephens, David W Boykin, W David Wilson

Nucleic Acids Res· September 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Heterocyclic diamidine interactions at AT base pairs in the DNA minor groove: effects of heterocycle differences, DNA AT sequence and length.
Yang Liu, Catharine J Collar, Arvind Kumar, Chad E Stephens, David W Boykin

J Phys Chem B· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis