Publications by authors named "Chamila Rupasinghe"

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Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer.
Chitta Ranjan Patra, Chamila N Rupasinghe, Shamit K Dutta, Santanu Bhattacharya, Enfeng Wang

ACS Chem Biol· October 2019

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Inhibition of N-Methyl-D-aspartate-induced Retinal Neuronal Death by Polyarginine Peptides Is Linked to the Attenuation of Stress-induced Hyperpolarization of the Inner Mitochondrial Membrane Potential.
John Marshall, Kwoon Y Wong, Chamila N Rupasinghe, Rakesh Tiwari, Xiwu Zhao

J Biol Chem· September 2015

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Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells.
Jun Yu, Chamila Rupasinghe, Jamie L Wilson, Linda Taylor, Nader Rahimi

Chem Biol Drug Des· May 2015

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A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death.
Octavian Bucur, Gabriel Gaidos, Achani Yatawara, Bodvael Pennarun, Chamila Rupasinghe

Sci Rep· May 2015

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Small-molecule inhibitors of JC polyomavirus infection.
Achani Yatawara, Gabriel Gaidos, Chamila N Rupasinghe, Bethany A O'Hara, Maria Pellegrini

J Pept Sci· March 2015

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Modulating the dysregulated migration of pulmonary arterial hypertensive smooth muscle cells with motif mimicking cell permeable peptides.
Jamie L Wilson, Chamila Rupasinghe, Anny Usheva, Rod Warburton, Chloe Kaplan

Curr Top Pept Protein Res· January 2015

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A cell permeable peptide targeting the intracellular loop 2 of endothelin B receptor reduces pulmonary hypertension in a hypoxic rat model.
Daniel S Green, Chamila Rupasinghe, Rod Warburton, Jamie L Wilson, Christine O Sallum

PLoS One· December 2014

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Gallic acid-based small-molecule inhibitors of JC and BK polyomaviral infection.
Bethany A O'Hara, Chamila Rupasinghe, Achani Yatawara, Gabriel Gaidos, Dale F Mierke

Virus Res· August 2014

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Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA.
Moninderpal Kaur, Chamila N Rupasinghe, Edvin Klosi, Mark R Spaller, Christine S Chow

Bioorg Med Chem· March 2013

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Enhancing and limiting endothelin-1 signaling with a cell-penetrating peptide mimicking the third intracellular loop of the ETB receptor.
Christine O Sallum, Jamie L Wilson, Chamila Rupasinghe, Eric Berg, Jun Yu

Chem Biol Drug Des· September 2012

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Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer.
Chitta Ranjan Patra, Chamila N Rupasinghe, Shamit K Dutta, Santanu Bhattacharya, Enfeng Wang

ACS Chem Biol· April 2012

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RGS-GAIP-interacting protein controls breast cancer progression.
Ling Wang, Julie S Lau, Chitta Ranjan Patra, Ying Cao, Santanu Bhattacharya, Chamila N Rupasinghe

Mol Cancer Res· December 2010

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T7 phage display as a method of peptide ligand discovery for PDZ domain proteins.
Sudhir C Sharma, Adnan Memic, Chamila N Rupasinghe, Anne-Cécile E Duc, Mark R Spaller

Biopolymers· June 2009

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Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth.
Michael H Muders, Pawan K Vohra, Shamit K Dutta, Enfeng Wang, Yasuhiro Ikeda, Chamila N Rupasinghe

Clin Cancer Res· June 2009

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Design, synthesis, and evaluation of linear and cyclic peptide ligands for PDZ10 of the multi-PDZ domain protein MUPP1.
Sudhir C Sharma, Chamila N Rupasinghe, Rachel B Parisien, Mark R Spaller

Biochemistry· November 2007

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A thermodynamic ligand binding study of the third PDZ domain (PDZ3) from the mammalian neuronal protein PSD-95.
Dorina Saro, Tao Li, Chamila Rupasinghe, Azrael Paredes, Nicole Caspers

Biochemistry· May 2007

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The interplay between structure-based design and combinatorial chemistry.
Chamila N Rupasinghe, Mark R Spaller

Curr Opin Chem Biol· June 2006

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Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane.
Nashaat Z Gerges, Donald S Backos, Chamila N Rupasinghe, Mark R Spaller, José A Esteban

EMBO J· April 2006

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