Publications by authors named "Chang Uk Lim"

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CDK8/19 inhibition attenuates G1 arrest induced by BCR-ABL antagonists and accelerates death of chronic myelogenous leukemia cells.
Alvina I Khamidullina, Margarita A Yastrebova, Alexandra V Bruter, Julia V Nuzhina, Nadezhda E Vorobyeva, Chang-Uk Lim

Cell Death Discov· February 2025

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Mediator kinase inhibition reverses castration resistance of advanced prostate cancer.
Jing Li, Thomas A Hilimire, Yueying Liu, Lili Wang, Jiaxin Liang, Chang-Uk Lim

J Clin Invest· March 2024

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RASSF1 is identified by transcriptome coordination analysis as a target of ATF4.
Youwen Zhang, Kim-Tuyen Huynh-Dam, Xiaokai Ding, Vitali Sikirzhytski, Chang-Uk Lim

FEBS Open Bio· March 2023

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Propensity to endoplasmic reticulum stress in deer mouse fibroblasts predicts skin inflammation and body weight gain.
Youwen Zhang, Chang-Uk Lim, Vitali Sikirzhytski, Asieh Naderi, Ioulia Chatzistamou

Dis Model Mech· October 2021

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The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs.
Amanda C Sharko, Chang-Uk Lim, Martina S J McDermott, Chuck Hennes, Kingsavanh P Philavong

Cells· January 2021

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CDK7 Inhibition is Effective in all the Subtypes of Breast Cancer: Determinants of Response and Synergy with EGFR Inhibition.
Martina S J McDermott, Amanda C Sharko, Jessica Munie, Susannah Kassler, Theresa Melendez, Chang-Uk Lim

Cells· March 2020

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CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases.
Jiaxin Liang, Mengqian Chen, Daniel Hughes, Alexander A Chumanevich, Serena Altilia, Chang-Uk Lim

Cancer Res· December 2018

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CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.
Mengqian Chen, Jiaxin Liang, Hao Ji, Zhengguan Yang, Serena Altilia, Chang-Uk Lim

Proc Natl Acad Sci U S A· September 2017

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Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer.
Martina S J McDermott, Alexander A Chumanevich, Chang-Uk Lim, Jiaxin Liang, Mengqian Chen

Oncotarget· February 2017

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Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.
Elina Levina, Hao Ji, Mengqiang Chen, Mirza Baig, David Oliver, Chang-uk Lim

Oncotarget· May 2015

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Tumor-derived mesenchymal stem cells and orthotopic site increase the tumor initiation potential of putative mouse mammary cancer stem cells derived from MMTV-PyMT mice.
Denise Grant Lanza, Jun Ma, Ian Guest, Chang Uk-Lim, Anna Glinskii

Tumour Biol· December 2012

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Characterization of mammary cancer stem cells in the MMTV-PyMT mouse model.
Jun Ma, Denise Grant Lanza, Ian Guest, Chang Uk-Lim, Anna Glinskii

Tumour Biol· December 2012

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Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
Donald C Porter, Elena Farmaki, Serena Altilia, Gary P Schools, Deborah K West, Chang-uk Lim

Proc Natl Acad Sci U S A· August 2012

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Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells.
Ruth E Gonzalez, Chang-Uk Lim, Kelly Cole, Christine Hanko Bianchini, Gary P Schools

Cell Cycle· October 2011

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Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders.
Anna B Glinskii, Shuang Ma, Jun Ma, Denise Grant, Chang-Uk Lim

Cell Cycle· October 2011

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Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1.
Michael Shtutman, Mirza Baig, Elina Levina, Gregory Hurteau, Chang-Uk Lim

Proc Natl Acad Sci U S A· July 2011

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Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system.
Hung-Yun Lin, Cornelia B Landersdorfer, David London, Ran Meng, Chang-Uk Lim

PLoS Comput Biol· February 2011

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Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders.
Anna B Glinskii, Jun Ma, Shuang Ma, Denise Grant, Chang-Uk Lim

Cell Cycle· December 2009

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Comparison of the mutagenic potential of 17 physical and chemical agents analyzed by the flow cytometry mutation assay.
C Tenley French, Carley D Ross, Stephen B Keysar, Dhanashree D Joshi, Chang-Uk Lim

Mutat Res· December 2006

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The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage.
Junqing Zhou, Chang Uk Lim, Jian Jian Li, Lu Cai, Ying Zhang

Cancer Lett· November 2006

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Cell cycle dependent apoptosis and cell cycle blocks induced by hyperthermia in HL-60 cells.
Chang-Uk Lim, Ying Zhang, Michael H Fox

Int J Hyperthermia· February 2006

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The role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint control.
Ying Zhang, Junqing Zhou, Chang Uk Lim

Cell Res· January 2006

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Assay to measure CD59 mutations in CHO A(L) cells using flow cytometry.
Carley D Ross, Chang-Uk Lim, Michael H Fox

Cytometry A· August 2005

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Effect of a membrane-targeted sphingosine kinase 1 on cell proliferation and survival.
Farida Safadi-Chamberlain, Li-Ping Wang, Shawn G Payne, Chang-Uk Lim, Suzanne Stratford

Biochem J· June 2005

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