Publications by authors named "Chang-Run Guo"

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Understanding interspecies drug response variations between human and rodent P2X7 receptors.
Chang-Run Guo, Danqi Sheng, Ji-Yuan Li, Tian-Tian Li, Jia-Bao Yao

Nat Commun· December 2025

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A shared mechanism for TNP-ATP recognition by members of the P2X receptor family.
Xiao-Bo Ma, Chen-Xi Yue, Yan Liu, Yang Yang, Jin Wang, Chang-Run Guo

Comput Struct Biotechnol J· December 2024

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Structural basis for inositol pyrophosphate gating of the phosphate channel XPR1.
Yi Lu, Chen-Xi Yue, Li Zhang, Deqiang Yao, Ying Xia, Chang-Run Guo

Science· November 2024

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Structural insights into the orthosteric inhibition of P2X receptors by non-ATP analog antagonists.
Danqi Sheng, Chen-Xi Yue, Fei Jin, Yao Wang, Muneyoshi Ichikawa, Chang-Run Guo

Elife· April 2024

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Chronic cough relief by allosteric modulation of P2X3 without taste disturbance.
Chang-Run Guo, Zhong-Zhe Zhang, Xing Zhou, Meng-Yang Sun, Tian-Tian Li

Nat Commun· September 2023

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Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors.
Xin Zhang, Meng-Yang Sun, Xue Zhang, Chang-Run Guo, Yun-Tao Lei

Front Mol Biosci· August 2022

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The long β2,3-sheets encoded by redundant sequences play an integral role in the channel function of P2X7 receptors.
Xue-Fei Ma, Ting-Ting Wang, Wen-Hui Wang, Li Guan, Chang-Run Guo

J Biol Chem· June 2022

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P2X3-selective mechanism of Gefapixant, a drug candidate for the treatment of refractory chronic cough.
Wen-Wen Cui, Si-Yu Wang, Yu-Qing Zhang, Yao Wang, Ying-Zhe Fan, Chang-Run Guo

Comput Struct Biotechnol J· March 2022

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Thymopentin-Mediated Inhibition of Cancer Stem Cell Stemness Enhances the Cytotoxic Effect of Oxaliplatin on Colon Cancer Cells.
Peng-Cheng Yu, Di Liu, Zeng-Xiang Han, Fang Liang, Cui-Yun Hao, Chang-Run Guo

Front Pharmacol· February 2022

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GSK1702934A and M085 directly activate TRPC6 via a mechanism of stimulating the extracellular cavity formed by the pore helix and transmembrane helix S6.
Pei-Lin Yang, Xing-Hua Li, Jin Wang, Xue-Fei Ma, Bo-Ying Zhou, Chang-Run Guo

J Biol Chem· October 2021

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A conserved residue in the P2X4 receptor has a nonconserved function in ATP recognition.
Ping-Fang Chen, Xue-Fei Ma, Liang-Fei Sun, Yun Tian, Ying-Zhe Fan, Chang-Run Guo

J Biol Chem· August 2021

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Altered allostery of the left flipper domain underlies the weak ATP response of rat P2X5 receptors.
Liang-Fei Sun, Yan Liu, Jin Wang, Li-Dong Huang, Yang Yang, Chang-Run Guo

J Biol Chem· December 2019

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Chemical constituents of Kopsia officinalis and their antagonizing high glucose-evoked podocyte injury activity.
Zhi-Wei Wang, Chang-Run Guo, Yun-Liang Lin, Hui-Jiao Yan, Yan Mu

Fitoterapia· September 2019

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The In vitro/vivo Evaluation of Prepared Gastric Floating Tablets of Berberine Hydrochloride.
Jun Ji, Xin He, Xiao-Lin Yang, Wen-Juan Du, Cheng-Long Cui, Chang-Run Guo

AAPS PharmSciTech· August 2017

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The enhancement mechanism of wine-processed Radix Scutellaria on NTG-induced migraine rats.
Cheng-Long Cui, Xin He, Cui-Lan Dong, Zi-Jing Song, Jun Ji, Chang-Run Guo

Biomed Pharmacother· July 2017

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Analgesia effect of baicalein against NTG-induced migraine in rats.
Xiao-Fan Zhang, Wen-Jun Zhang, Cui-Lan Dong, Wan-Li Hu, Yu-Yao Sun, Chang-Run Guo

Biomed Pharmacother· June 2017

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Anti-arthritic effect of berberine on adjuvant-induced rheumatoid arthritis in rats.
Xue Wang, Xin He, Chun-Feng Zhang, Chang-Run Guo, Chong-Zhi Wang

Biomed Pharmacother· May 2017

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Gastroprotective Effect of Alkaloids from Cortex Phellodendri on Gastric Ulcers in Rats through Neurohumoral Regulation.
Ling Wang, Xue Wang, Xiao-Ming Zhu, Yan-Qi Liu, Wen-Juan Du, Chang-Run Guo

Planta Med· February 2017

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Gastroprotective effect of palmatine against acetic acid-induced gastric ulcers in rats.
Ling Wang, Xue Wang, Su-Li Zhang, Xiao-Ming Zhu, Yan-Qi Liu, Chang-Run Guo

J Nat Med· January 2017

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Timosaponin B-II ameliorates diabetic nephropathy via TXNIP, mTOR, and NF-κB signaling pathways in alloxan-induced mice.
Yong-Liang Yuan, Chang-Run Guo, Ling-Ling Cui, Shi-Xia Ruan, Chun-Feng Zhang

Drug Des Devel Ther· September 2016

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Palmatine from Mahonia bealei attenuates gut tumorigenesis in ApcMin/+ mice via inhibition of inflammatory cytokines.
Wei-Kun Ma, Hui Li, Cui-Lan Dong, Xin He, Chang-Run Guo

Mol Med Rep· July 2016

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Study on the anti-gout activity of chlorogenic acid: improvement on hyperuricemia and gouty inflammation.
Zhao-Qing Meng, Zhao-Hui Tang, Yun-Xia Yan, Chang-Run Guo, Liang Cao

Am J Chin Med· August 2015

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Antioxidative Activity of Flavonoids from Abrus cantoniensis against Ethanol-Induced Gastric Ulcer in Mice.
Hui Li, Zi-Jing Song, Yan-Ping Dai, Su-Li Zhang, Xin He, Chang-Run Guo

Planta Med· July 2015

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