Publications by authors named "Changhao Bi"

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Mini and enhanced CRISPR activators for cancer therapies.
Meiyu Huang, Keshan Wang, Anshu Li, Xiagu Zhu, Zuping Zhou, Changhao Bi

J Adv Res· September 2025

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Optimized dual-AAV base editor delivery system with enhanced editing efficiency and virion production titer.
Wenjia Yu, Yujie Wang, Siwei Li, Yingcai Dai, Yucheng Li, Changhao Bi

Synth Syst Biotechnol· September 2025

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The Advancement of Prime Editing Technology.
Lu Zhang, Dongdong Zhao, Zhandong Wei, Xiao Zhu, Taixin Sha, Changhao Bi

Chembiochem· June 2025

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Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity.
Chao Yang, Qingxiao Fang, Mengyu Li, Jin Zhang, Rui Li, Chongbiao Huang, Changhao Bi

Nat Commun· June 2025

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[Oncolytic virus-mediated base editing for targeted killing of cervical cancer cells].
Huanhuan Xu, Siwei Li, Xi Luo, Zuping Zhou, Changhao Bi

Sheng Wu Gong Cheng Xue Bao· April 2025

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Mismatch prime editing gRNA increased efficiency and reduced indels.
Jidong Fei, Dongdong Zhao, Caiyi Pang, Ju Li, Siwei Li, Changhao Bi

Nat Commun· January 2025

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[Development of a tumor organoid culture system with peptide-based hydrogels].
Huibin Wang, Dongdong Zhao, Lu Zhang, Zhandong Wei, Jun Liang, Changhao Bi

Sheng Wu Gong Cheng Xue Bao· November 2024

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Glycosylase-based base editors for efficient T-to-G and C-to-G editing in mammalian cells.
Lijun Ye, Dongdong Zhao, Ju Li, Yiran Wang, Bo Li, Huibin Wang, Changhao Bi

Nat Biotechnol· October 2024

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Engineering of HEK293T Cell Factory for Lentiviral Production by High-Throughput Selected Genes.
Zhang Xinyue, Siwei Li, Wang Yujie, Dai Yingcai, Bi Changhao

CRISPR J· October 2024

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Mutagenesis techniques for evolutionary engineering of microbes - exploiting CRISPR-Cas, oligonucleotides, recombinases, and polymerases.
Anna Zimmermann, Julian E Prieto-Vivas, Karin Voordeckers, Changhao Bi, Kevin J Verstrepen

Trends Microbiol· September 2024

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igRNA Prediction and Selection AI Models (igRNA-PS) for Bystander-less ABE Base Editing.
Bo Li, Xiagu Zhu, Dongdong Zhao, Yaqiu Li, Yuanzhao Yang, Changhao Bi

J Mol Biol· September 2024

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Engineering Escherichia coli for utilization of PET degraded ethylene glycol as sole feedstock.
Junxi Chi, Pengju Wang, Yidan Ma, Xingmiao Zhu, Leilei Zhu, Changhao Bi

Biotechnol Biofuels Bioprod· September 2024

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Exploring the NMN Biosynthesis as an Alternative Pathway to Enhance NMN Production.
Pengju Wang, Yidan Ma, Ju Li, Junchang Su, Junxi Chi, Changhao Bi

ACS Synth Biol· August 2024

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Genomic allele-specific base editing with imperfect gRNA.
Xuxu Chen, Dongdong Zhao, Xueting Hou, Ju Li, Shiming Pu, Changhao Bi

J Genet Genomics· October 2023

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Targeted C-to-T and A-to-G dual mutagenesis system for RhtA transporter evolution.
Zhandong Wei, Dongdong Zhao, Jie Wang, Ju Li, Ning Xu, Changhao Bi

Appl Environ Microbiol· October 2023

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High-throughput base editing KO screening of cellular factors for enhanced GBE.
Jie Yang, Dongdong Zhao, Xiagu Zhu, Yuanzhao Yang, Bo Li, Chang-Hao Bi

J Genet Genomics· August 2023

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AAV-mediated base-editing therapy ameliorates the disease phenotypes in a mouse model of retinitis pigmentosa.
Yidong Wu, Xiaoling Wan, Dongdong Zhao, Xuxu Chen, Yujie Wang, Changhao Bi

Nat Commun· August 2023

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Developing a PAM-Flexible CRISPR-Mediated Dual-Deaminase Base Editor to Regulate Extracellular Electron Transport in .
Tailin Wang, Jiwei Zhang, Liang Wei, Dongdong Zhao, Changhao Bi

ACS Synth Biol· June 2023

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Obtaining the best igRNAs for bystander-less correction of all ABE-reversible pathogenic SNVs using high-throughput screening.
Bo Li, Dongdong Zhao, Yaqiu Li, Yuanzhao Yang, Xiagu Zhu, Changhao Bi

Mol Ther· April 2023

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HMGN1 enhances CRISPR-directed dual-function A-to-G and C-to-G base editing.
Chao Yang, Zhenzhen Ma, Keshan Wang, Xingxiao Dong, Meiyu Huang, Changhao Bi

Nat Commun· April 2023

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Artificial Diploid Escherichia coli by a CRISPR Chromosome-Doubling Technique.
Pengju Wang, Dongdong Zhao, Ju Li, Junchang Su, Chunzhi Zhang, Changhao Bi

Adv Sci (Weinh)· March 2023

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Circular Guide RNA for Improved Stability and CRISPR-Cas9 Editing Efficiency and in Bacteria.
Li Liu, Wenbo Li, Ju Li, Dongdong Zhao, Siwei Li, Changhao Bi

ACS Synth Biol· February 2023

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Enhancement of a prime editing system via optimal recruitment of the pioneer transcription factor P65.
Ronghao Chen, Yu Cao, Yajing Liu, Dongdong Zhao, Ju Li, Changhao Bi

Nat Commun· January 2023

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[Artificial bioconversion of carbon dioxide].
Tao Cai, Yuwan Liu, Leilei Zhu, Hao Su, Yu Wang, Changhao Bi

Sheng Wu Gong Cheng Xue Bao· November 2022

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[Application of genome editing technology in industrial microorganisms: current status and perspectives].
Chao Yang, Xingxiao Dong, Xueli Zhang, Changhao Bi

Sheng Wu Gong Cheng Xue Bao· November 2022

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