Publications by authors named "Changkun Hu"

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E0703 targets ERβ to facilitate the upregulation of GLI3, thereby alleviating irradiation-induced DNA damage on lymphocytes.
Zebin Liao, Liangliang Zhang, Zekun Wu, Changkun Hu, Xianglin Tang

Cell Mol Biol Lett· November 2025

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Determination of PSA by a label-free fluorescent aptasensor based on the on and off of the AIEE effect.
Yanjun Lu, Yulong Ju, Qiukai Tang, Yiwen Yang, Zhuowei Fu, Changkun Hu

Talanta· October 2025

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Direct observation of interdependent and hierarchical kinetochore assembly on individual centromeres.
Changkun Hu, Andrew R Popchock, Angelica Andrade Latino, Charles L Asbury, Sue Biggins

Nucleic Acids Res· October 2025

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Direct observation of interdependent and hierarchical kinetochore assembly on individual centromeres.
Changkun Hu, Andrew R Popchock, Angelica Andrade Latino, Charles L Asbury, Sue Biggins

bioRxiv· June 2025

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Detecting carcinoembryonic antigen based on the aggregation-induced emission enhancement effect.
Yanjun Lu, Mengqi Wang, Yiwen Yang, Qiukai Tang, Yanbo Zeng, Changkun Hu, Zhuowei Fu

Chem Commun (Camb)· November 2024

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Ferulic Acid Interferes with Radioactive Intestinal Injury Through the DJ-1-Nrf2 and Sirt1-NF-κB-NLRP3 Pathways.
Xuemei Zhang, Haoyu Zhang, Mingyue Huang, Yu Mei, Changkun Hu, Congshu Huang, Huiting Zhang, Zengchun Ma

Molecules· October 2024

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Cannabidiol mitigates radiation-induced intestine ferroptosis via facilitating the heterodimerization of RUNX3 with CBFβ thereby promoting transactivation of GPX4.
Congshu Huang, Liangliang Zhang, Pan Shen, Zekun Wu, Gaofu Li, Yijian Huang, Changkun Hu, Renzeng Quzhuo, Chaoji Huangfu

Free Radic Biol Med· September 2024

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Alleviation of Splenic Injury by CB001 after Low-Dose Irradiation Mediated by NLRP3/Caspase-1-BAX/Caspase-3 Axis.
Changkun Hu, Zebin Liao, Liangliang Zhang, Zengchun Ma, Chengrong Xiao, Shuai Shao

Radiat Res· February 2024

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Beta human papillomavirus 8E6 promotes alternative end joining.
Changkun Hu, Taylor Bugbee, Rachel Palinski, Ibukun A Akinyemi, Michael T McIntosh

Elife· January 2023

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Ferulic acid produces neuroprotection against radiation-induced neuroinflammation by affecting NLRP3 inflammasome activation.
Guifang Liu, Yao Nie, Congshu Huang, Guihua Zhu, Xuemei Zhang, Changkun Hu, Zhihui Li, Zengchun Ma

Int J Radiat Biol· September 2022

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Beta HPV Deregulates Double-Strand Break Repair.
Changkun Hu, Nicholas Wallace

Viruses· April 2022

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Mechanisms modulating the activities of intestinal stem cells upon radiation or chemical agent exposure.
Zebin Liao, Changkun Hu, Yue Gao

J Radiat Res· March 2022

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Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter.
Changkun Hu, Tyler Doerksen, Taylor Bugbee, Nicholas A Wallace, Rachel Palinski

J Vis Exp· March 2022

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Beta human papillomavirus 8 E6 allows colocalization of non-homologous end joining and homologous recombination repair factors.
Changkun Hu, Taylor Bugbee, Dalton Dacus, Rachel Palinski, Nicholas Wallace

PLoS Pathog· February 2022

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Effect of antioxidants coenzyme Q10 and β-carotene on the cytotoxicity of vemurafenib against human malignant melanoma.
Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang

Oncol Lett· March 2021

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Beta Human Papillomavirus 8E6 Attenuates Non-Homologous End Joining by Hindering DNA-PKcs Activity.
Changkun Hu, Taylor Bugbee, Monica Gamez, Nicholas A Wallace

Cancers (Basel)· August 2020

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β-HPV 8E6 Attenuates ATM and ATR Signaling in Response to UV Damage.
Jazmine A Snow, Vaibhav Murthy, Dalton Dacus, Changkun Hu, Nicholas A Wallace

Pathogens· November 2019

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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy.
Vaibhav Murthy, Dalton Dacus, Monica Gamez, Changkun Hu, Sebastian O Wendel

J Vis Exp· June 2018

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Synergism of Dam, MutH, and MutS in methylation-directed mismatch repair in Escherichia coli.
Changkun Hu, Yunqi Zhao, Huiyun Sun, Yixin Yang

Mutat Res· January 2017

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Design and synthesis of chloroquine analogs with anti-breast cancer property.
V R Solomon, Changkun Hu, Hoyun Lee

Eur J Med Chem· September 2010

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A 4-aminoquinoline derivative that markedly sensitizes tumor cell killing by Akt inhibitors with a minimum cytotoxicity to non-cancer cells.
Changkun Hu, V Raja Solomon, Pablo Cano, Hoyun Lee

Eur J Med Chem· February 2010

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Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach.
V Raja Solomon, Changkun Hu, Hoyun Lee

Bioorg Med Chem· February 2010

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Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.
Feng He, Lan Mo, Xiao-Yong Zheng, Changkun Hu, Herbert Lepor

Cancer Res· December 2009

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Hybrid pharmacophore design and synthesis of isatin-benzothiazole analogs for their anti-breast cancer activity.
V Raja Solomon, Changkun Hu, Hoyun Lee

Bioorg Med Chem· November 2009

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The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine.
Changkun Hu, V Raja Solomon, Gerardo Ulibarri, Hoyun Lee

Bioorg Med Chem· September 2008

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