Publications by authors named "Changpu Yu"

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Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia.
Fu Li, May Kung Sutherland, Changpu Yu, Roland B Walter, Lori Westendorf

Mol Cancer Ther· February 2018

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Therapeutic potential of SGN-CD19B, a PBD-based anti-CD19 drug conjugate, for treatment of B-cell malignancies.
Maureen C Ryan, Maria Corinna Palanca-Wessels, Brian Schimpf, Kristine A Gordon, Heather Kostner, Changpu Yu

Blood· November 2017

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5-azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia.
May Kung Sutherland, Changpu Yu, Martha Anderson, Weiping Zeng, Nico van Rooijen

MAbs· April 2015

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SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML.
May S Kung Sutherland, Roland B Walter, Scott C Jeffrey, Patrick J Burke, Changpu Yu

Blood· August 2013

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Anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia.
May Kung Sutherland, Changpu Yu, Timothy S Lewis, Jamie B Miyamoto, Carol A Morris-Tilden

MAbs· April 2010

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Lysosomal trafficking and cysteine protease metabolism confer target-specific cytotoxicity by peptide-linked anti-CD30-auristatin conjugates.
May S Kung Sutherland, Russell J Sanderson, Kristine A Gordon, Jamie Andreyka, Charles G Cerveny, Changpu Yu

J Biol Chem· April 2006

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Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins.
David G Winkler, May S Kung Sutherland, Ethan Ojala, Eileen Turcott, James C Geoghegan, Changpu Yu

J Biol Chem· January 2005

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Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation.
May Kung Sutherland, James C Geoghegan, Changpu Yu, Eileen Turcott, John E Skonier

Bone· October 2004

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Noggin and sclerostin bone morphogenetic protein antagonists form a mutually inhibitory complex.
David G Winkler, Changpu Yu, James C Geoghegan, Ethan W Ojala, John E Skonier

J Biol Chem· August 2004

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Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts.
May Kung Sutherland, James C Geoghegan, Changpu Yu, David G Winkler, John A Latham

Bone· August 2004

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Osteocyte control of bone formation via sclerostin, a novel BMP antagonist.
David G Winkler, May Kung Sutherland, James C Geoghegan, Changpu Yu, Trenton Hayes

EMBO J· December 2003

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Establishment, characterization, and long-term maintenance of cultures of human fetal hepatocytes.
Catherine A Lázaro, Emma J Croager, Claudia Mitchell, Jean S Campbell, Changpu Yu

Hepatology· November 2003

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