Publications by authors named "Chaquip D Netto"

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Antitumor Potential of the Pterocarpanoquinone-Quinone LQB-472 in Prostate Cancer Cells.
Thayssa G Farias, Rachell R C Thimoteo, Felipe C Demidoff, Alcides J M da Silva, Marcia S Dos Santos, Chaquip D Netto

Cell Biochem Biophys· December 2025

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Activity of Pterocarpanquinone LQB-118 on and Its Impact on Parasite Bioenergetics.
Bruno F Azevedo, Andréia C S Brito, Johnata A Vilarim, Bianca D Ventura, Michely A P Mendes, Chaquip D Netto

ACS Omega· August 2025

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Evaluation of sugar meal administered anti-Leishmania compounds on the vectorial capacity of the vector, Lutzomyia longipalpis.
Tainá Neves Ferreira, Samara Graciane Costa Latgé, Tadeu Diniz Ramos, Felipe Cerqueira Demidoff, Edézio Ferreira Cunha-Júnior, Chaquip Daher Netto

PLoS One· June 2025

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Immunomodulatory Effects of Pterocarpanquinone LQB-118 in Murine Peritoneal Macrophages.
Éssia de Almeida Lima, Luiz Henrique Agra Cavalcante-Silva, Deyse Cristina Madruga Carvalho, Mariana Mendonça Soares, Anna Beatriz Araujo Medeiros, Chaquip Daher Netto

Immunol Invest· May 2025

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Novel Ru(II)-bipyridine/phenanthroline-lapachol complexes as potential anti-cancer agents.
Rone Aparecido De Grandis, Analu Rocha Costa, Carlos André Ferreira Moraes, Natália Zaneti Sampaio, Igor Henrique Cerqueira, Chaquip Daher Netto

J Inorg Biochem· December 2022

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Effects of anti-Leishmania compounds in the behavior of the sand fly vector Lutzomyia longipalpis.
Tainá Neves Ferreira, Reginaldo Peçanha Brazil, Mary Ann McDowell, Edézio Ferreira Cunha-Júnior, Paulo Roberto Ribeiro Costa, Chaquip Daher Netto

Pest Manag Sci· July 2022

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The pterocarpanquinone LQB‑118 compound induces apoptosis of cytarabine‑resistant acute myeloid leukemia cells.
Thaís Hancio, Luciano Mazzoccoli, Gustavo Guimarães, Marcela Robaina, Bruna Dos Santos Mendonça, Chaquip Daher Netto

Int J Oncol· June 2021

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Lapachol in the Design of a New Ruthenium(II)-Diphosphine Complex as a Promising Anticancer Metallodrug.
Katia M Oliveira, João Honorato, Felipe C Demidoff, Mario S Schultz, Chaquip D Netto

J Inorg Biochem· January 2021

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The pterocarpanquinone LQB 118 inhibits inflammation triggered by zymosan in vivo and in vitro.
Éssia de Almeida Lima, Luiz Henrique Agra Cavalcante-Silva, Deyse Cristina Madruga Carvalho, Chaquip Daher Netto, Paulo Roberto Ribeiro Costa

Int Immunopharmacol· June 2020

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LQB‑118 compound inhibits migration and induces cell death in glioblastoma cells.
Paula Sabbo Bernardo, Gustavo Henrique C Guimarães, Fernanda Costas C De Faria, Gabriel M Da Cunha Longo, Giselle P De Faria Lopes, Chaquip Daher Netto

Oncol Rep· January 2020

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Second-generation pterocarpanquinones: synthesis and antileishmanial activity.
Viviane Dos Santos Faiões, Lívia C R M da Frota, Edézio Ferreira Cunha-Junior, Julio C F Barcellos, Thayssa Da Silva, Chaquip Daher Netto

J Venom Anim Toxins Incl Trop Dis· November 2018

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Preparative chiral separation and absolute configuration of the synthetic pterocarpanquinone LQB-118.
Gabriel S Scatena, Neila M Cassiano, Chaquip D Netto, Paulo R R Costa, Quezia B Cass

Chirality· May 2017

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In vitro and in vivo antineoplastic and immunological effects of pterocarpanquinone LQB-118.
Eduardo J Salustiano, Matheus L Dumas, Gabriel G Silva-Santos, Chaquip D Netto, Paulo R R Costa

Invest New Drugs· October 2016

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Anti-inflammatory properties of pterocarpanquinone LQB-118 in mice.
Ingred G Riça, Chaquip D Netto, Magdalena N Rennó, Paula A Abreu, Paulo R R Costa

Bioorg Med Chem· September 2016

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Preclinical Studies Evaluating Subacute Toxicity and Therapeutic Efficacy of LQB-118 in Experimental Visceral Leishmaniasis.
Edézio Ferreira Cunha-Júnior, Thiago Martino Martins, Marilene Marcuzzo Canto-Cavalheiro, Paulo Roberto Marques, Elyzabeth Avvad Portari, Chaquip Daher Netto

Antimicrob Agents Chemother· June 2016

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Further evidence that naphthoquinone inhibits Toxoplasma gondii growth in vitro.
Luciana Lemos Rangel da Silva, Juliana de Araujo Portes, Marlon Heggdorne de Araújo, Jéssica Lays Sant'ana Silva, Magdalena Nascimento Rennó, Chaquip Daher Netto

Parasitol Int· December 2015

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The pterocarpanquinone LQB-118 inhibits tumor cell proliferation by downregulation of c-Myc and cyclins D1 and B1 mRNA and upregulation of p21 cell cycle inhibitor expression.
Thiago Martino, Fernanda C J Magalhães, Graça A Justo, Marsen G P Coelho, Chaquip D Netto

Bioorg Med Chem· June 2014

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LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis.
Grazielle Alves Ribeiro, Edézio Ferreira Cunha-Júnior, Roberta Olmo Pinheiro, Silvia Amaral Gonçalves da-Silva, Marilene Marcuzzo Canto-Cavalheiro, Chaquip Daher Netto

J Antimicrob Chemother· April 2013

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A new type of pterocarpanquinone that affects Toxoplasma gondii tachyzoites in vitro.
Juliana de Araujo Portes, Chaquip Daher Netto, Alcides José Monteiro da Silva, Paulo Roberto Ribeiro Costa, Renato Augusto DaMatta

Vet Parasitol· May 2012

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LQB-118, a pterocarpanquinone structurally related to lapachol [2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone]: a novel class of agent with high apoptotic effect in chronic myeloid leukemia cells.
Raquel C Maia, Flavia C Vasconcelos, Thiago de Sá Bacelar, Eduardo J Salustiano, Luis Felipe R da Silva, Chaquip D Netto

Invest New Drugs· December 2011

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Pterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis.
Camilla D Buarque, Gardenia C G Militão, Daisy J B Lima, Leticia V Costa-Lotufo, Cláudia Pessoa, Chaquip D Netto

Bioorg Med Chem· November 2011

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Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis.
Edézio Ferreira da Cunha-Júnior, Wallace Pacienza-Lima, Grazielle Alves Ribeiro, Chaquip Daher Netto, Marilene Marcuzzo do Canto-Cavalheiro

J Antimicrob Chemother· July 2011

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Comparison of the cytotoxic effect of lapachol, alpha-lapachone and pentacyclic 1,4-naphthoquinones on human leukemic cells.
Eduardo J S Salustiano, Chaquip D Netto, Renata F Fernandes, Alcides J M da Silva, Thiago S Bacelar

Invest New Drugs· April 2010

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New pterocarpanquinones: synthesis, antineoplasic activity on cultured human malignant cell lines and TNF-alpha modulation in human PBMC cells.
Chaquip D Netto, Alcides J M da Silva, Eduardo J S Salustiano, Thiago S Bacelar, Ingred G Riça

Bioorg Med Chem· February 2010

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(+/-)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan and derivatives: cytotoxic effect on human leukemia cell lines.
Chaquip D Netto, Eduardo S J Santos, Carolina Pereira Castro, Alcides J M da Silva, Vivian M Rumjanek

Eur J Med Chem· February 2009

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