Publications by authors named "Charlene P Poore"

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Development and in vitro characterization of humanized antibodies for blocking human TRPM4 channel.
Shunhui Wei, Charlene Priscilla Poore, Ravi Kumar Verma, See Wee Low, Bo Chen

Sci Rep· June 2025

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Enhanced isradipine sensitivity in vascular smooth muscle cells due to hypoxia-induced Ca1.2 splicing and RbFox1/Fox2 downregulation.
Charlene Priscilla Poore, Jialei Yang, Shunhui Wei, Chee Kong Fhu, Zoë Bichler

FEBS J· October 2024

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evaluation of monoclonal antibody M4M using a humanised rat model of stroke demonstrates attenuation of reperfusion injury via blocking human TRPM4 channel.
Charlene Priscilla Poore, Shunhui Wei, Bo Chen, See Wee Low, Jeslyn Si Qi Tan

J Drug Target· April 2024

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TRPM4 blocking antibody reduces neuronal excitotoxicity by specifically inhibiting glutamate-induced calcium influx under chronic hypoxia.
Charlene P Poore, Nurul A M N Hazalin, Shunhui Wei, See Wee Low, Bo Chen

Neurobiol Dis· February 2024

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SLC26A11 Inhibition Reduces Oncotic Neuronal Death and Attenuates Stroke Reperfusion Injury.
Shunhui Wei, Bo Chen, See Wee Low, Charlene Priscilla Poore, Yahui Gao

Mol Neurobiol· October 2023

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TRPM4 Blocking Antibody Protects Cerebral Vasculature in Delayed Stroke Reperfusion.
Bo Chen, Shunhui Wei, See Wee Low, Charlene Priscilla Poore, Andy Thiam-Huat Lee

Biomedicines· May 2023

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Binding epitope for recognition of human TRPM4 channel by monoclonal antibody M4M.
Shunhui Wei, Julian Behn, Charlene Priscilla Poore, See Wee Low, Bernd Nilius

Sci Rep· November 2022

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Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia.
Shunhui Wei, See Wee Low, Charlene Priscilla Poore, Bo Chen, Yahui Gao

Front Cell Dev Biol· October 2020

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Curcumin Ameliorates Neuroinflammation, Neurodegeneration, and Memory Deficits in p25 Transgenic Mouse Model that Bears Hallmarks of Alzheimer's Disease.
Jeyapriya Raja Sundaram, Charlene Priscilla Poore, Noor Hazim Bin Sulaimee, Tej Pareek, Wei Fun Cheong

J Alzheimers Dis· July 2018

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Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo.
Jeyapriya Raja Sundaram, Charlene Priscilla Poore, Noor Hazim Bin Sulaimee, Tej Pareek, A B M A Asad

J Neurosci· January 2013

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Cdk5/p25-induced cytosolic PLA2-mediated lysophosphatidylcholine production regulates neuroinflammation and triggers neurodegeneration.
Jeyapriya R Sundaram, Elizabeth S Chan, Charlene P Poore, Tej K Pareek, Wei Fun Cheong

J Neurosci· January 2012

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Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity.
Charlene P Poore, Jeyapriya R Sundaram, Tej K Pareek, Amy Fu, Niranjana Amin

J Neurosci· June 2010

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