Publications by authors named "Charles Abrams"

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The ASH Research Collaborative Sickle Cell Disease Research Network: Past, Present and Future.
Fuad El Rassi, Biree Andemariam, Abdullah Kutlar, Betty Sue Pace, Aliza Fink, Charles S Abrams

Blood Adv· September 2025

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Molecular dynamics simulation of GJC2 mutants reveal pathogenic mechanisms of PMLD1 and SPG44.
David Gong, Jennifer L Orthmann-Murphy, Deepak Kumar, Gabriel D Dungan, Ayman W El-Hattab, Charles K Abrams

J Gen Physiol· July 2025

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β-actin function in platelets and red blood cells can be performed by γ-actin and is therefore independent of actin isoform protein sequence.
Devasmita Chakravarty, Pavan Vedula, Megan Coffin, Li Chen, Stephanie Sterling, Charles S Abrams

Mol Biol Cell· February 2025

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Cemdomespib Therapy Slows the Progression of Neuromuscular Weakness and Demyelination in the R75W-Connexin 32 Animal Model of Charcot-Marie-Tooth 1X Disease.
Ryan M Lang, Riddhi Chawla, Sugandha Patel, Charles K Abrams, Rick T Dobrowsky

ACS Pharmacol Transl Sci· January 2025

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COVID-19 mRNA vaccination responses in individuals with sickle cell disease: an ASH RC Sickle Cell Research Network Study.
Alan R Anderson, John J Strouse, Deepa Manwani, Amanda M Brandow, Elliott Vichinsky, Charles S Abrams

Blood Adv· September 2024

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Assessment of blood-brain barrier leakage and brain oxygenation in Connexin-32 knockout mice with systemic neuroinflammation using pulse electron paramagnetic resonance imaging techniques.
Boris Epel, Navin Viswakarma, Safa Hameed, Mona M Freidin, Charles K Abrams

Magn Reson Med· June 2024

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Individual phosphatidylinositol transfer proteins have distinct functions that do not involve lipid transfer activity.
Liang Zhao, Chelsea L Thorsheim, Aae Suzuki, Timothy J Stalker, Sang H Min, Charles S Abrams

Blood Adv· August 2023

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New ASH initiatives to improve patient care in the long-overlooked sickle cell disease.
Venée N Tubman, Narla Mohandas, Charles S Abrams

Blood· July 2023

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Mechanisms of Diseases Associated with Mutation in GJC2/Connexin 47.
Charles K Abrams

Biomolecules· April 2023

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Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models.
Xu Han, Yang Mei, Rama K Mishra, Honghao Bi, Atul D Jain, Charles S Abrams

J Clin Invest· March 2023

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Knock-in mouse models for CMTX1 show a loss of function phenotype in the peripheral nervous system.
Charles K Abrams, Eunjoo Lancaster, Jian J Li, Gabriel Dungan, David Gong

Exp Neurol· February 2023

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Pharmacologic Targeting of the C-Terminus of Heat Shock Protein 90 Improves Neuromuscular Function in Animal Models of Charcot Marie Tooth X1 Disease.
Sukhmanjit Kaur, Xinyue Zhang, Sugandha Patel, Yssa A Rodriguez, Kylie J Luther, Charles K Abrams

ACS Pharmacol Transl Sci· February 2023

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SARS-CoV-2 Vaccination-Induced Thrombotic Thrombocytopenia: A Rare but Serious Immunologic Complication.
Charles S Abrams, Geoffrey D Barnes

Annu Rev Med· January 2023

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Genotype-phenotype correlations and disease mechanisms in PEX13-related Zellweger spectrum disorders.
Paola Borgia, Simona Baldassari, Nicoletta Pedemonte, Ebba Alkhunaizi, Gianluca D'Onofrio, Charles K Abrams

Orphanet J Rare Dis· July 2022

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Activation of the unfolded protein response by Connexin47 mutations associated with Pelizaeus-Merzbacher-like disease.
Rafael E Flores-Obando, Mona M Freidin, A Iván Hernández, Charles K Abrams

Mol Cell Neurosci· May 2022

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AAV1.NT-3 gene therapy for X-linked Charcot-Marie-Tooth neuropathy type 1.
Burcak Ozes, Morgan Myers, Kyle Moss, Jennifer Mckinney, Alicia Ridgley, Charles K Abrams

Gene Ther· April 2022

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Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19.
Sokratis A Apostolidis, Amrita Sarkar, Heather M Giannini, Rishi R Goel, Divij Mathew, Charles S Abrams

Front Immunol· March 2022

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Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice.
Carla Casu, Alison Liu, Gianluca De Rosa, Audrey Low, Aae Suzuki, Charles Abrams

PLoS One· January 2022

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ASH Research Collaborative: a real-world data infrastructure to support real-world evidence development and learning healthcare systems in hematology.
William A Wood, Peter Marks, Robert M Plovnick, Kathleen Hewitt, Donna S Neuberg, Charles S Abrams

Blood Adv· December 2021

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Investigating oligodendrocyte connexins: Heteromeric interactions between Cx32 and mutant or wild-type forms of Cx47 do not contribute to or modulate gap junction function.
Charles K Abrams, Rafael E Flores-Obando, Gabriel D Dungan, Elina Cherepanova, Mona M Freidin

Glia· August 2021

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Effects of early crush on aging wild type and Connexin 32 knockout mice: Evidence for a neuroprotective state in CMT1X mouse nerve.
Alejandro Peinado, Samantha L Asche-Godin, Mona M Freidin, Charles K Abrams

J Peripher Nerv Syst· June 2021

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Pleckstrin-2 is essential for erythropoiesis in β-thalassemic mice, reducing apoptosis and enhancing enucleation.
Maria Feola, Andrea Zamperone, Daniel Moskop, Huiyong Chen, Carla Casu, Charles S Abrams

Commun Biol· May 2021

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Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19.
Sokratis A Apostolidis, Amrita Sarkar, Heather M Giannini, Rishi R Goel, Divij Mathew, Charles S Abrams

bioRxiv· May 2021

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PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice.
Sang Hee Min, Aae Suzuki, Lehn Weaver, Jessica Guzman, Yutein Chung, Charles S Abrams

Mol Cell Biol· November 2019

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