Publications by authors named "Charles D Chen"

Claim this Profile
J
Joint spatial associations of amyloid beta and tau pathology in Down syndrome and preclinical Alzheimer's disease: Cross-sectional associations with early cognitive impairments.
Jessie Fanglu Fu, Arun Garimella, Alex Lapointe, William W T Aye, Charles D Chen

Alzheimers Dement· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN-TU-001 trial.
Austin McCullough, Charles D Chen, Brian A Gordon, Nelly Joseph-Mathurin, Clifford R Jack, Chengjie Xiong

Alzheimers Dement· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease.
Charles D Chen, Erin E Franklin, Yan Li, Nelly Joseph-Mathurin, Aime L Burns, Chengjie Xiong, Jie Chen

Acta Neuropathol· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Î
γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).
Stephanie A Schultz, Lei Liu, Aaron P Schultz, Colleen D Fitzpatrick, Raina Levin, Charles D Chen, Chengjie Xiong

Lancet Neurol· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease.
Michelle E Farrell, Emma G Thibault, J Alex Becker, Julie C Price, Brian C Healy, Charles D Chen

Alzheimers Dement· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Disease staging of Alzheimer's disease using a CSF-based biomarker model.
Gemma Salvadó, Kanta Horie, Nicolas R Barthélemy, Jacob W Vogel, Alexa Pichet Binette, Charles D Chen, Andrew J Aschenbrenner

Nat Aging· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging.
Stephanie Doering, Austin McCullough, Brian A Gordon, Charles D Chen, Nicole McKay, Chengjie Xiong, Andrew J Aschenbrenner

EBioMedicine· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage.
Nelly Joseph-Mathurin, Rebecca L Feldman, Ruijin Lu, Zahra Shirzadi, Carmen Toomer, Charles D Chen, Gengsheng Chen, Chengjie Xiong

Alzheimers Dement· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests.
Nicolas R Barthélemy, Gemma Salvadó, Suzanne E Schindler, Yingxin He, Shorena Janelidze, Charles D Chen

Nat Med· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease.
Stephanie A Schultz, Zahra Shirzadi, Aaron P Schultz, Lei Liu, Colleen D Fitzpatrick, Charles D Chen, Chengjie Xiong

Aging Cell· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN).
Nicole S McKay, Brian A Gordon, Russ C Hornbeck, Aylin Dincer, Shaney Flores, Charles D Chen, Chengjie Xiong

Nat Neurosci· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease.
Kanta Horie, Gemma Salvadó, Nicolas R Barthélemy, Shorena Janelidze, Yan Li, Charles D Chen

Nat Med· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Longitudinal head-to-head comparison of C-PiB and F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease.
Charles D Chen, Austin McCullough, Brian Gordon, Nelly Joseph-Mathurin, Shaney Flores, Chengjie Xiong

Eur J Nucl Med Mol Imaging· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's disease.
Gemma Salvadó, Kanta Horie, Nicolas R Barthélemy, Jacob W Vogel, Alexa Pichet Binette, Charles D Chen, Andrew J Aschenbrenner

medRxiv· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparing Tau PET Visual Interpretation with Tau PET Quantification, Cerebrospinal Fluid Biomarkers, and Longitudinal Clinical Assessment.
Charles D Chen, Maria Rosana Ponisio, Jordan A Lang, Shaney Flores, Suzanne E Schindler

J Alzheimers Dis· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigating Tau and Amyloid Tracer Skull Binding in Studies of Alzheimer Disease.
Shaney Flores, Charles D Chen, Yi Su, Aylin Dincer, Sarah J Keefe

J Nucl Med· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study.
Anna H Boerwinkle, Brian A Gordon, Julie Wisch, Shaney Flores, Rachel L Henson, Charles D Chen, Chengjie Xiong

Lancet Neurol· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease.
Nelly Joseph-Mathurin, Jorge J Llibre-Guerra, Yan Li, Austin A McCullough, Carsten Hofmann, Charles D Chen, Chengjie Xiong

Ann Neurol· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluation of dose-dependent treatment effects after mid-trial dose escalation in biomarker, clinical, and cognitive outcomes for gantenerumab or solanezumab in dominantly inherited Alzheimer's disease.
Guoqiao Wang, Yan Li, Chengjie Xiong, Eric McDade, David B Clifford, Andrew J Aschenbrenner, Charles D Chen

Alzheimers Dement (Amst)· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression.
Aylin Dincer, Charles D Chen, Nicole S McKay, Lauren N Koenig, Austin McCullough

Sci Transl Med· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Intracranial internal carotid artery calcification is not predictive of future cognitive decline.
Farzaneh Rahmani, Marina Nguyen, Charles D Chen, Nicole McKay, Aylin Dincer, Gengsheng Chen

Alzheimers Res Ther· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease.
Charles D Chen, Nelly Joseph-Mathurin, Namita Sinha, Aihong Zhou, Yan Li, Chengjie Xiong

Acta Neuropathol· October 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Temporal Correlation of CSF and Neuroimaging in the Amyloid-Tau-Neurodegeneration Model of Alzheimer Disease.
Anna H Boerwinkle, Julie K Wisch, Charles D Chen, Brian A Gordon, Omar H Butt

Neurology· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease.
Charles D Chen, Timothy R Holden, Brian A Gordon, Erin E Franklin, Yan Li

Ann Clin Transl Neurol· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novelty, Salience, and Surprise Timing Are Signaled by Neurons in the Basal Forebrain.
Kaining Zhang, Charles D Chen, Ilya E Monosov

Curr Biol· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis