Publications by authors named "Charles D Lopez"

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Early detection of pancreatic cancer by a high-throughput protease-activated nanosensor assay.
Jose L Montoya Mira, Arnaud Quentel, Ranish K Patel, Dove Keith, Megan Sousa, Jessica Minnier, Benjamin R Kingston, Larry David, Sadik C Esener, Rosalie C Sears

Sci Transl Med· February 2025

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Tumor-intrinsic MHC-II activation in pancreatic ductal adenocarcinoma enhances immune response and treatment efficacy.
Canping Chen, Kyle P Gribbin, Xi Li, Tugba Y Ozmen, Furkan Ozmen, Charles D Lopez

bioRxiv· October 2025

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MYC Serine 62 phosphorylation promotes its binding to DNA double strand breaks to facilitate repair and cell survival under genotoxic stress.
Gabriel M Cohn, Colin J Daniel, Jennifer R Eng, Xiao-Xin Sun, Carl Pelz, Charles D Lopez

bioRxiv· March 2025

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Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer.
Jason M Link, Jennifer R Eng, Carl Pelz, Kevin MacPherson-Hawthorne, Patrick J Worth, Charles D Lopez

Nat Cancer· January 2025

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Devimistat (CPI-613) With Modified Fluorouarcil, Oxaliplatin, Irinotecan, and Leucovorin (FFX) Versus FFX for Patients With Metastatic Adenocarcinoma of the Pancreas: The Phase III AVENGER 500 Study.
Philip A Philip, Vaibhav Sahai, Nathan Bahary, Amit Mahipal, Anup Kasi, Charles D Lopez

J Clin Oncol· November 2024

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CASPER: A Phase I trial combining calaspargase pegol-mnkl and cobimetinib in pancreatic cancer.
Charles D Lopez, Adel Kardosh, Emerson Y Chen, Guillaume Pegna, Alexander Guimaraes

Future Oncol· November 2024

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A Modified Floxuridine Reduced-Dose Protocol for Patients with Unresectable Colorectal Liver Metastases Treated with Hepatic Arterial Infusion.
Issac R Schwantes, Ranish K Patel, Adel Kardosh, Jillian Paxton, Robert Eil, Charles D Lopez

Ann Surg Oncol· October 2024

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ASO Author Reflections: Is It Time to Re-evaluate Floxuridine Dosing for Hepatic Arterial Infusion?
Issac R Schwantes, Ranish K Patel, Adel Kardosh, Charles D Lopez, Skye C Mayo

Ann Surg Oncol· October 2024

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Gastroenteropancreatic neuroendocrine tumors: Epigenetic landscape and clinical implications.
Hannah S McMurry, Jaydira Del Rivero, Emerson Y Chen, Adel Kardosh, Charles D Lopez

Curr Probl Cancer· October 2024

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Circulating Neoplastic-Immune Hybrid Cells Are Biomarkers of Occult Metastasis and Treatment Response in Pancreatic Cancer.
Ranish K Patel, Michael Parappilly, Hannah C Farley, Emile J Latour, Lei G Wang, Charles D Lopez

Cancers (Basel)· October 2024

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Neoadjuvant immunotherapy leads to complete pathologic response in locally advanced colon cancer.
Lyndsey Sandow, Liana Tsikitis, Charles D Lopez, Brian Brinkerhoff, Adel Kardosh

Clin Case Rep· August 2024

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Exploratory Analyses of Circulating Neoplastic-Immune Hybrid Cells as Prognostic Biomarkers in Advanced Intrahepatic Cholangiocarcinoma.
Ranish K Patel, Michael S Parappilly, Brett S Walker, Robert T Heussner, Alice Fung, Charles D Lopez

Int J Mol Sci· August 2024

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Hepatectomy is associated with improved oncologic outcomes in recurrent colorectal liver metastases: A propensity-matched analysis.
Thomas L Sutton, Liam H Wong, Brett S Walker, Elizabeth N Dewey, Robert Eil, Charles D Lopez

Surgery· June 2023

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Atezolizumab Plus PEGPH20 Versus Chemotherapy in Advanced Pancreatic Ductal Adenocarcinoma and Gastric Cancer: MORPHEUS Phase Ib/II Umbrella Randomized Study Platform.
Andrew H Ko, Kyu-Pyo Kim, Jens T Siveke, Charles D Lopez, Jill Lacy

Oncologist· June 2023

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Phase 2 study of preoperative chemotherapy with nab-paclitaxel and gemcitabine followed by chemoradiation for borderline resectable or node-positive pancreatic ductal adenocarcinoma.
Emerson Y Chen, Adel Kardosh, Nima Nabavizadeh, Bryan Foster, Skye C Mayo, Charles D Lopez

Cancer Med· June 2023

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Efficacy and safety of maintenance therapy with pamiparib versus placebo for advanced gastric cancer responding to first-line platinum-based chemotherapy: Phase 2 study results.
Fortunato Ciardiello, Yung-Jue Bang, Andrés Cervantes, Mikhail Dvorkin, Charles D Lopez

Cancer Med· June 2023

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Adjuvant -Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, Phase III Trial.
Margaret A Tempero, Uwe Pelzer, Eileen M O'Reilly, Jordan Winter, Do-Youn Oh, Charles D Lopez

J Clin Oncol· April 2023

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Socioeconomic and Geographic Disparities in the Referral and Treatment of Pancreatic Cancer at High-Volume Centers.
Thomas L Sutton, Blake Beneville, Alicia J Johnson, Skye C Mayo, Erin W Gilbert, Charles D Lopez

JAMA Surg· March 2023

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Modulation of myeloid and T cells in vivo by Bruton's tyrosine kinase inhibitor ibrutinib in patients with metastatic pancreatic ductal adenocarcinoma.
Meenal Sinha, Courtney Betts, Li Zhang, Madeline J Griffith, Isabelle Solman, Charles D Lopez

J Immunother Cancer· January 2023

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Hepatic arterial infusion pump chemotherapy combined with systemic therapy for patients with advanced colorectal liver metastases: Outcomes in a newly established program.
Brett S Walker, Kevin G Billingsley, Thomas L Sutton, Kenneth J Kolbeck, Elena K Korngold, Charles D Lopez

J Surg Oncol· September 2022

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Therapy Resistant Gastroenteropancreatic Neuroendocrine Tumors.
Kristen McClellan, Emerson Y Chen, Adel Kardosh, Charles D Lopez, Jaydira Del Rivero

Cancers (Basel)· September 2022

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Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS).
Vasileia Tsintari, Bianca Walter, Falko Fend, Mathis Overkamp, Christian Rothermundt, Charles D Lopez

BMC Cancer· July 2022

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Neoadjuvant Therapy Is Associated with Improved Chemotherapy Delivery and Overall Survival Compared to Upfront Resection in Pancreatic Cancer without Increasing Perioperative Complications.
Christopher Ryan Deig, Thomas Lee Sutton, Blake Beneville, Kristin Trone, Amanda Stratton, Charles D Lopez

Cancers (Basel)· January 2022

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Geographic Disparities in Referral Rates and Oncologic Outcomes of Intrahepatic Cholangiocarcinoma: A Population-Based Study.
Thomas L Sutton, Brett S Walker, Nima Nabavizadeh, Aaron Grossberg, Charles R Thomas, Charles D Lopez

Ann Surg Oncol· December 2021

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ASPP2κ Is Expressed In Human Colorectal Carcinoma And Promotes Chemotherapy Resistance And Tumorigenesis.
Ingmar Rieger, Vasileia Tsintari, Mathis Overkamp, Falko Fend, Charles D Lopez

Front Mol Biosci· November 2021

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