Publications by authors named "Charles D Smith"

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Dynamic proportional loss of functional connectivity revealed change of left superior frontal gyrus in subjective cognitive decline: an explanatory study based on Chinese and Western cohorts.
Luyao Wang, Wenjing Hu, Fan Dong, Can Sheng, Jinglong Wu, Charles D Smith, Karen Elizabeth Smith, Amanda Smith

Geroscience· August 2025

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Reduction of TRAIL-Induced Mcl-1 and cIAP2 by c-Myc or Sorafenib Sensitizes Resistant Human Cancer Cells to TRAIL-Induced Death.
M Stacey Ricci, Seok-Hyun Kim, Kazuhiro Ogi, John P Plastaras, Jianhua Ling, Charles D Smith

Cancer Cell· August 2025

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Opaganib Promotes Weight Loss and Suppresses High-Fat Diet-Induced Obesity and Glucose Intolerance.
Lynn W Maines, Staci N Keller, Ryan A Smith, Charles D Smith

Diabetes Metab Syndr Obes· April 2025

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Three-stage hybrid spiking neural networks fine-tuning for speech enhancement.
Nidal Abuhajar, Zhewei Wang, Marc Baltes, Ye Yue, Li Xu, Charles D Smith

Front Neurosci· April 2025

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Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells.
Lynn W Maines, Staci N Keller, Ryan A Smith, Randy S Schrecengost, Charles D Smith

Cancers (Basel)· May 2024

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The Sphingolipid-Modulating Drug Opaganib Protects against Radiation-Induced Lung Inflammation and Fibrosis: Potential Uses as a Medical Countermeasure and in Cancer Radiotherapy.
Lynn W Maines, Staci N Keller, Ryan A Smith, Cecelia L Green, Charles D Smith

Int J Mol Sci· February 2024

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Opioid cutting agents for use as internal standards in ion mobility spectrometry (IMS).
Charles D Smith, Braden C Giordano

Talanta· December 2023

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Spiking neural networks fine-tuning for brain image segmentation.
Ye Yue, Marc Baltes, Nidal Abuhajar, Tao Sun, Avinash Karanth, Charles D Smith

Front Neurosci· November 2023

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Opaganib (ABC294640) Induces Immunogenic Tumor Cell Death and Enhances Checkpoint Antibody Therapy.
Lynn W Maines, Staci N Keller, Charles D Smith

Int J Mol Sci· November 2023

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The Sphingosine Kinase 2 Inhibitor Opaganib Protects Against Acute Kidney Injury in Mice.
Lynn W Maines, Cecelia L Green, Staci N Keller, Leo R Fitzpatrick, Charles D Smith

Int J Nephrol Renovasc Dis· November 2022

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Opaganib Protects against Radiation Toxicity: Implications for Homeland Security and Antitumor Radiotherapy.
Lynn W Maines, Randy S Schrecengost, Yan Zhuang, Staci N Keller, Ryan A Smith, Charles D Smith

Int J Mol Sci· October 2022

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Recent Progress in the Development of Opaganib for the Treatment of Covid-19.
Charles D Smith, Lynn W Maines, Staci N Keller, Vered Katz Ben-Yair, Reza Fathi

Drug Des Devel Ther· July 2022

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Memory-Related Frontal Brainwaves Predict Transition to Mild Cognitive Impairment in Healthy Older Individuals Five Years Before Diagnosis.
Yang Jiang, Juan Li, Frederick A Schmitt, Gregory A Jicha, Nancy B Munro, Charles D Smith

J Alzheimers Dis· September 2021

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Development of a protocol to assess within-subject, regional white matter hyperintensity changes in aging and dementia.
Ahmed A Bahrani, Charles D Smith, Justin M Barber, Omar M Al-Janabi, David K Powell

J Neurosci Methods· August 2021

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Characteristics of VCP mutation-associated cardiomyopathy.
Stephani C Wang, Charles D Smith, Dawn M Lombardo, Virginia Kimonis

Neuromuscul Disord· August 2021

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Support loading effects on the performance of an extraction chromatographic resin: Toward improved separation of trivalent lanthanides.
Charles D Smith, Mark L Dietz

Talanta· January 2021

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Diffuse optical assessment of cerebral-autoregulation in older adults stratified by cerebrovascular risk.
Ahmed A Bahrani, Weikai Kong, Yu Shang, Chong Huang, Charles D Smith

J Biophotonics· October 2020

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Analysis of selective target engagement by small-molecule sphingosine kinase inhibitors using the Cellular Thermal Shift Assay (CETSA).
Jeremy A Hengst, Taryn E Dick, Charles D Smith, Jong K Yun

Cancer Biol Ther· September 2020

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Brain structure changes over time in normal and mildly impaired aged persons.
Charles D Smith, Linda J Van Eldik, Gregory A Jicha, Frederick A Schmitt, Peter T Nelson

AIMS Neurosci· May 2020

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Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β1-42 and Hypertension.
Omar M Al-Janabi, Christopher A Brown, Ahmed A Bahrani, Erin L Abner, Justin M Barber, Charles D Smith

J Alzheimers Dis· November 2019

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Post-acquisition processing confounds in brain volumetric quantification of white matter hyperintensities.
Ahmed A Bahrani, Omar M Al-Janabi, Erin L Abner, Shoshana H Bardach, Richard J Kryscio, Charles D Smith

J Neurosci Methods· November 2019

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Targeting Sphingosine Kinases for the Treatment of Cancer.
Clayton S Lewis, Christina Voelkel-Johnson, Charles D Smith

Adv Cancer Res· September 2019

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Distinct patterns of default mode and executive control network circuitry contribute to present and future executive function in older adults.
Christopher A Brown, Frederick A Schmitt, Charles D Smith, Brian T Gold

Neuroimage· July 2019

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White Matter Hyperintensity Regression: Comparison of Brain Atrophy and Cognitive Profiles with Progression and Stable Groups.
Omar M Al-Janabi, Christopher E Bauer, Larry B Goldstein, Richard R Murphy, Ahmed A Bahrani, Charles D Smith

Brain Sci· July 2019

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Age and Alzheimer's pathology disrupt default mode network functioning via alterations in white matter microstructure but not hyperintensities.
Christopher A Brown, Yang Jiang, Charles D Smith, Brian T Gold

Cortex· July 2018

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