Publications by authors named "Charles Isaacs"

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Open-label pilot study of oral methylprednisolone for the treatment of patients with friedreich ataxia.
Maya Patel, Kimberly Schadt, Ashley McCormick, Charles Isaacs, Yi Na Dong

Muscle Nerve· November 2019

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Roles of Mitochondrial 17β-Hydroxysteroid Dehydrogenase Type 10 in Alzheimer's Disease.
Xue-Ying He, Charles Isaacs, Song-Yu Yang

J Alzheimers Dis· February 2019

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Vaginal Product Formulation Alters the Innate Antiviral Activity and Glycome of Cervicovaginal Fluids with Implications for Viral Susceptibility.
Sujeethraj Koppolu, Linlin Wang, Ayushi Mathur, Jayeshwar A Nigam, Charlene S Dezzutti, Charles Isaacs

ACS Infect Dis· November 2018

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Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich's ataxia patients.
Daniel Nachun, Fuying Gao, Charles Isaacs, Cassandra Strawser, Zhongan Yang

Hum Mol Genet· September 2018

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Double-blind, randomized and controlled trial of EPI-743 in Friedreich's ataxia.
Theresa Zesiewicz, Jason L Salemi, Susan Perlman, Kelly L Sullivan, Jessica D Shaw, Charles Isaacs

Neurodegener Dis Manag· August 2018

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Impact of Mobility Device Use on Quality of Life in Children With Friedreich Ataxia.
Resham Ejaz, Shiyi Chen, Charles J Isaacs, Amanda Carnevale, Judith Wilson

J Child Neurol· May 2018

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Selected missense mutations impair frataxin processing in Friedreich ataxia.
Elisia Clark, Jill S Butler, Charles J Isaacs, Marek Napierala, David R Lynch

Ann Clin Transl Neurol· August 2017

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Effects of genetic severity on glucose homeostasis in Friedreich ataxia.
Charles J Isaacs, Karlla W Brigatti, Olena Kucheruk, Sarah Ratcliffe, Tom Sciascia

Muscle Nerve· November 2016

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Progression of Friedreich ataxia: quantitative characterization over 5 years.
Maya Patel, Charles J Isaacs, Lauren Seyer, Karlla Brigatti, Sarah Gelbard

Ann Clin Transl Neurol· September 2016

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Friedreich Ataxia and nephrotic syndrome: a series of two patients.
Julianna E Shinnick, Charles J Isaacs, Sharon Vivaldi, Kimberly Schadt, David R Lynch

BMC Neurol· January 2016

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The effect of menopause on the innate antiviral activity of cervicovaginal lavage.
Catherine A Chappell, Charles E Isaacs, Weimin Xu, Leslie A Meyn, Kevin Uranker

Am J Obstet Gynecol· August 2015

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Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders.
Song-Yu Yang, Xue-Ying He, Charles Isaacs, Carl Dobkin, David Miller

J Steroid Biochem Mol Biol· September 2014

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Theaflavin-3,3'-digallate and lactic acid combinations reduce herpes simplex virus infectivity.
Charles E Isaacs, Weimin Xu

Antimicrob Agents Chemother· August 2013

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Development of a liposome microbicide formulation for vaginal delivery of octylglycerol for HIV prevention.
Lin Wang, Alexandra Beumer Sassi, Dorothy Patton, Charles Isaacs, B J Moncla

Drug Dev Ind Pharm· August 2012

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Digallate dimers of (-)-epigallocatechin gallate inactivate herpes simplex virus.
Charles E Isaacs, Weimin Xu, George Merz, Sharon Hillier, Lisa Rohan

Antimicrob Agents Chemother· December 2011

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Characterization of cyclodextrin inclusion complexes of the anti-HIV non-nucleoside reverse transcriptase inhibitor UC781.
Haitao Yang, Michael A Parniak, Charles E Isaacs, Sharon L Hillier, Lisa C Rohan

AAPS J· December 2008

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Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products.
Alexandra B Sassi, Charles E Isaacs, Bernard J Moncla, Phalguni Gupta, Sharon L Hillier

J Pharm Sci· August 2008

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Killing of Neisseria gonorrhoeae, Streptococcus agalactiae (group B streptococcus), Haemophilus ducreyi, and vaginal Lactobacillus by 3-O-octyl-sn-glycerol.
B J Moncla, K Pryke, Charles E Isaacs

Antimicrob Agents Chemother· April 2008

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Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus.
Charles E Isaacs, Guang Y Wen, Weimin Xu, Jun Hua Jia, Lisa Rohan

Antimicrob Agents Chemother· March 2008

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Use of frozen-thawed cervical tissues in the organ culture system to measure anti-HIV activities of candidate microbicides.
Phalguni Gupta, Deena Ratner, Bruce K Patterson, Kathy Kulka, Lisa C Rohan, Charles E Isaacs

AIDS Res Hum Retroviruses· May 2006

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Inactivation of herpes simplex virus clinical isolates by using a combination microbicide.
Charles E Isaacs, Lisa Rohan, Weimin Xu, Jun Hua Jia, Timothy Mietzner

Antimicrob Agents Chemother· March 2006

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Human milk inactivates pathogens individually, additively, and synergistically.
Charles E Isaacs

J Nutr· May 2005

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A lipid-peptide microbicide inactivates herpes simplex virus.
Charles E Isaacs, Jun Hua Jia, Weimin Xu

Antimicrob Agents Chemother· August 2004

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Specific and nonspecific protective factors in milk: why don't they prevent viral transmission during breastfeeding?
Charles E Isaacs

Adv Exp Med Biol· January 2003

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Antimicrobial activity of lipids added to human milk, infant formula, and bovine milk.
Charles E. Isaacs, Richard E. Litov, Halldor Thormar

J Nutr Biochem· July 1995

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