Publications by authors named "Charles Mackay"

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Synthesis, in vivo colon-targeted delivery effect and gut microbiota modulation of indole-acetylated starches derived from various native starch structures.
Qian Gong, Bin Wang, Mei Guo, Yisheng Zhao, Xinyan Qu, Charles R Mackay

Carbohydr Polym· November 2025

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Reduced Expression of MTSS1 Increases Sarcomere Number and Improves Contractility in Select Forms of Monogenic DCM.
Hannah Kleppe, Anastasia Budan, Luke Zhang, Marie Majetic, Reva Shenwai, Charles E MacKay

JACC Basic Transl Sci· November 2025

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pH-sensor GPR68 plays a role in how dietary fibre lowers blood pressure in a preclinical model of hypertension.
Evany Dinakis, Chudan Xu, Rikeish R Muralitharan, Hamdi Jama, Liang Xie, Charles R Mackay

Clin Sci (Lond)· October 2025

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Preintervention Intake of Whole Grains Versus Refined Grains, and the Gut Microbiome, Discriminate the Antihypertensive Effect of Prebiotic Fiber.
Matthew Snelson, Dakota Rhys-Jones, Hamdi A Jama, Darren J Creek, Charles R Mackay

Circ Genom Precis Med· October 2025

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Near-infrared light driven photodynamic therapy by hyaluronic acid encapsulated ionic polymer integrated with oxygen self-supply and high acetate supplement for chronic wound healing.
Yanhong Li, Qiang Zhang, Binqiu Duan, Xinyan Qu, Mei Guo, Charles R Mackay

Int J Biol Macromol· June 2025

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Gut Microbiota Metabolites Sensed by Host GPR41/43 Protect Against Hypertension.
Rikeish R Muralitharan, Tenghao Zheng, Evany Dinakis, Liang Xie, Anastasia Barbaro-Wahl, Charles R Mackay

Circ Res· February 2025

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Chemokine receptor CXCR7 antagonism ameliorates cardiac and renal fibrosis induced by mineralocorticoid excess.
Bing H Wang, Remy Robert, Francine Z Marques, Niwanthi Rajapakse, Helen Kiriazis, Charles R Mackay

Sci Rep· November 2024

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Dietary therapy of murine primary biliary cholangitis induces hepatocellular steatosis: A cautionary tale.
Weici Zhang, Taha Al Tekreeti, Patrick S C Leung, Koichi Tsuneyama, Harleen Dhillon, Charles R Mackay

Liver Int· October 2024

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Author Correction: Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice.
Sara Ranjbarvaziri, Aliya Zeng, Iris Wu, Amara Greer-Short, Farshad Farshidfar, Charles E MacKay

Nat Commun· October 2024

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Indole-3-Acetic Acid Esterified with Waxy, Normal, and High-Amylose Maize Starches: Comparative Study on Colon-Targeted Delivery and Intestinal Health Impact.
Qian Gong, Xinyan Qu, Yisheng Zhao, Xingjing Zhang, Shuhua Cao, Charles R Mackay

Nutrients· October 2024

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Influence of angiotensin II on the gut microbiome: modest effects in comparison to experimental factors.
Rikeish R Muralitharan, Michael E Nakai, Matthew Snelson, Tenghao Zheng, Evany Dinakis, Charles R Mackay

Cardiovasc Res· September 2024

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Maternal Diet and Gut Microbiota Influence Predisposition to Cardiovascular Disease in Offspring.
Hamdi A Jama, Malathi S I Dona, Evany Dinakis, Michael Nakai, Madeleine R Paterson, Charles R Mackay

Circ Res· August 2024

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A Butyrate-Yielding Dietary Supplement Prevents Acute Alcoholic Liver Injury by Modulating Nrf2-Mediated Hepatic Oxidative Stress and Gut Microbiota.
Qi Xu, Mei Guo, Haidi Wang, Haitao Liu, Yunbo Wei, Charles R Mackay

Int J Mol Sci· August 2024

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High metabolite concentrations in portal venous blood as a possible mechanism for microbiota effects on the immune system and Western diseases.
Quanbo Wang, Charles R Mackay

J Allergy Clin Immunol· April 2024

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Indole-3-acetic acid ameliorates dextran sulfate sodium-induced colitis via the ERK signaling pathway.
Xinyan Qu, Yingying Song, Qingjun Li, Qi Xu, Yanru Li, Charles R Mackay

Arch Pharm Res· March 2024

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Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice.
Sara Ranjbarvaziri, Aliya Zeng, Iris Wu, Amara Greer-Short, Farshad Farshidfar, Charles E MacKay

Nat Commun· February 2024

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The Relationship between Liver Volume, Clinicopathological Characteristics and Survival in Patients Undergoing Resection with Curative Intent for Non-Metastatic Colonic Cancer.
Josh McGovern, Charles Mackay, Rhiannon Freireich, Allan M Golder, Ross D Dolan

Tomography· February 2024

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GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development.
Duan Ni, Jian Tan, Remy Robert, Jemma Taitz, Anjie Ge, Charles Mackay

Eur J Immunol· November 2023

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Dietary Fiber Improves Skin Wound Healing and Scar Formation through the Metabolite-Sensing Receptor GPR43.
Maria Cecilia Campos Canesso, Puebla Cassini-Vieira, Camila Francisco Moreira, Suzanne Luong, Milene Alvarenga Rachid, Charles Reay Mackay

J Invest Dermatol· September 2023

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Human CXCR1 knock-in mice infer functional expression of a murine ortholog.
Farnaz Fahimi, Md Jahangir Alam, Caroline Ang, Galih Prakasa Adhyatma, Liang Xie, Charles R Mackay

J Leukoc Biol· September 2023

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Dietary Fiber and Microbiota Metabolite Receptors Enhance Cognition and Alleviate Disease in the 5xFAD Mouse Model of Alzheimer's Disease.
Yichen Zhou, Liang Xie, Jan Schröder, Iona S Schuster, Michael Nakai, Charles R Mackay

J Neurosci· September 2023

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Neflamapimod inhibits endothelial cell activation, adhesion molecule expression, leukocyte attachment and vascular inflammation by inhibiting p38 MAPKα and NF-κB signaling.
Sreelakshmi N Menon, Farzana Zerin, Emmanuella Ezewudo, Nimi P Simon, Sreeranjini N Menon, Charles E Mackay

Biochem Pharmacol· August 2023

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Vasodilators mobilize SK3 channels in endothelial cells to produce arterial relaxation.
Dieniffer Peixoto-Neves, Shambhu Yadav, Charles E MacKay, Ulrich C Mbiakop, Alejandro Mata-Daboin

Proc Natl Acad Sci U S A· August 2023

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Immunomodulatory Effects of Microbiota-Derived Short-Chain Fatty Acids in Autoimmune Liver Diseases.
Weici Zhang, Charles R Mackay, M Eric Gershwin

J Immunol· June 2023

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A major mechanism for immunomodulation: Dietary fibres and acid metabolites.
Liang Xie, Md Jahangir Alam, Francine Z Marques, Charles R Mackay

Semin Immunol· March 2023

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