Publications by authors named "Charles Mann"

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Research in Reverse: When scientists make sharp 180-degree turns in their thinking, it is often for one of two particular reasons.
Charles C Mann

Sci Am· September 2025

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Multiscale fiber remodeling in the infarcted left ventricle using a stress-based reorientation law.
Mohammad Mehri, Hossein Sharifi, Charles K Mann, Alexus L Rockward, Kenneth S Campbell

Acta Biomater· November 2024

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Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease.
Hossein Sharifi, Mohammad Mehri, Charles K Mann, Kenneth S Campbell, Lik Chuan Lee

Ann Biomed Eng· August 2024

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Measuring the PULSE of Nursing: Development of a Dashboard to Evaluate and Monitor Nursing Care Models.
Charles Mann, Lorraine Montoya, Joey Taylor, Glenn Barton

J Nurs Care Qual· May 2024

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Reproducibility of Systolic Strain in Mice Using Cardiac Magnetic Resonance Feature Tracking of Black-Blood Cine Images.
Hossein Sharifi, Charles K Mann, Ahmed Z Noor, Amir Nikou, Connor R Ferguson

Cardiovasc Eng Technol· December 2022

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A multiscale model of the cardiovascular system that regulates arterial pressure via closed loop baroreflex control of chronotropism, cell-level contractility, and vascular tone.
Hossein Sharifi, Charles K Mann, Jonathan F Wenk, Kenneth S Campbell

Biomech Model Mechanobiol· December 2022

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Multiscale simulations of left ventricular growth and remodeling.
Hossein Sharifi, Charles K Mann, Alexus L Rockward, Mohammad Mehri, Joy Mojumder

Biophys Rev· October 2021

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Force-dependent recruitment from myosin OFF-state increases end-systolic pressure-volume relationship in left ventricle.
Charles K Mann, Lik Chuan Lee, Kenneth S Campbell, Jonathan F Wenk

Biomech Model Mechanobiol· December 2020

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Enhancing Nursing Capacity to Provide Patient Care in a Pandemic.
Lorraine Montoya, Trishia Jonathan, Ann Mitchell, Lori Delaney, Lisa Freeman, Charles Mann

Nurs Leadersh (Tor Ont)· December 2020

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CAPAbility: comparison of the JOURNEY II Bi-Cruciate Stabilised and GENESIS II total knee arthroplasty in performance and functional ability: protocol of a randomised controlled trial.
Celia Clarke, Valerie Pomeroy, Allan Clark, Graham Creelman, Nicola Hancock, Charles Mann

Trials· February 2020

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Stiffness post-total knee replacement: A proof of principle study investigating the effect of gene expression analysis of markers of fibrosis.
Charles J Mann, Anne M Bradley, Eleanor R Jones, Iain R McNamara, Toby O Smith

Knee· August 2019

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Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).
David J O'Neill, Adedayo Adedoyin, Jenifer A Bray, Darlene C Deecher, Andrew Fensome, Charles Mann

J Med Chem· October 2011

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Discovery of novel selective norepinephrine reuptake inhibitors: 4-[3-aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231).
David J O'Neill, Adedayo Adedoyin, Peter D Alfinito, Jenifer A Bray, Scott Cosmi, Charles Mann

J Med Chem· June 2010

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Synthesis and biological evaluation of piperazinyl heterocyclic antagonists of the gonadotropin releasing hormone (GnRH) receptor.
Matthew D Vera, Joseph T Lundquist, Murty V Chengalvala, Joshua E Cottom, Irene B Feingold, Charles W Mann, John F Mehlmann

Bioorg Med Chem Lett· April 2010

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Sutures versus staples for skin closure in orthopaedic surgery: meta-analysis.
Toby O Smith, Debbie Sexton, Charles Mann, Simon Donell

BMJ· March 2010

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Bed exercises following total hip replacement: 1 year follow-up of a single-blinded randomised controlled trial.
Toby O Smith, Charles J V Mann, Allan Clark, Simon T Donell

Hip Int· February 2010

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Anthropology. Chagnon critics overstepped bounds, historian says.
Charles C Mann

Science· December 2009

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Addicted to rubber.
Charles C Mann

Science· July 2009

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Small molecule antagonists of the gonadotropin-releasing hormone (GnRH) receptor: structure-activity relationships of small heterocyclic groups appended to the 2-phenyl-4-piperazinyl-benzimidazole template.
Diane B Hauze, Murty V Chengalvala, Joshua E Cottom, Irene B Feingold, Lloyd Garrick, Charles W Mann, John F Mehlmann

Bioorg Med Chem Lett· April 2009

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Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): an orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R).
Jeffrey C Pelletier, Murty V Chengalvala, Joshua E Cottom, Irene B Feingold, Daniel M Green, Charles W Mann, John F Mehlmann

J Med Chem· April 2009

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(S)-N-(5-Chlorothiophene-2-sulfonyl)-beta,beta-diethylalaninol a Notch-1-sparing gamma-secretase inhibitor.
Derek C Cole, Joseph R Stock, Anthony F Kreft, Madelene Antane, Suzan H Aschmies, Charles W Mann

Bioorg Med Chem Lett· February 2009

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Archaeology. Ancient earthmovers of the Amazon.
Charles C Mann

Science· August 2008

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Archaeology. The western Amazon's "garden cities".
Charles C Mann

Science· August 2008

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2-phenyl-4-piperazinylbenzimidazoles: orally active inhibitors of the gonadotropin releasing hormone (GnRH) receptor.
Jeffrey C Pelletier, Murty Chengalvala, Josh Cottom, Irene Feingold, Lloyd Garrick, Charles Mann, John Mehlmann

Bioorg Med Chem· July 2008

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Discovery of a novel series of Notch-sparing gamma-secretase inhibitors.
Anthony Kreft, Boyd Harrison, Suzan Aschmies, Kevin Atchison, David Casebier, Charles Mann

Bioorg Med Chem Lett· July 2008

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