Publications by authors named "Charles Pendley"

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A novel approach to evaluate the pharmacokinetic biocomparability of a monoclonal antibody derived from two different cell lines using simultaneous crossover design.
Chao Han, Thomas S McIntosh, Brian J Geist, Trina Jiao, Thomas A Puchalski, Charles E Pendley

AAPS J· January 2014

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A novel approach for the simultaneous quantification of a therapeutic monoclonal antibody in serum produced from two distinct host cell lines.
Brian J Geist, Darryl Davis, Thomas McIntosh, Tong-Yuan Yang, Kenneth Goldberg, Charles Pendley

MAbs· July 2013

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Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab.
Jacqueline M Benson, Clifford W Sachs, George Treacy, Honghui Zhou, Charles E Pendley

Nat Biotechnol· July 2011

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Bioanalytical interferences in immunoassays for antibody biotherapeutics.
Charles Pendley, Gopi Shankar

Bioanalysis· April 2011

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Multiple-dose pharmacokinetics and safety of an ibuprofen-pseudoephedrine cold suspension in children.
Cathy K Gelotte, Mary Jane Prior, Charles Pendley, Brenda Zimmerman, Bernard J Lavins

Clin Pediatr (Phila)· July 2010

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Positive treatment effects of ustekinumab in psoriasis: analysis of lesional and systemic parameters.
Manjula Reddy, Gisela Torres, Thomas McCormick, Colleen Marano, Kevin Cooper, Charles Pendley

J Dermatol· May 2010

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Population pharmacokinetics of golimumab, an anti-tumor necrosis factor-alpha human monoclonal antibody, in patients with psoriatic arthritis.
Zhenhua Xu, Thuy Vu, Howard Lee, Chuanpu Hu, Jie Ling, Charles Pendley

J Clin Pharmacol· September 2009

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Changes in biomarkers of inflammation and bone turnover and associations with clinical efficacy following infliximab plus methotrexate therapy in patients with early rheumatoid arthritis.
Sudha Visvanathan, Joseph C Marini, Josef S Smolen, E William St Clair, Charles Pritchard, Charles Pendley

J Rheumatol· July 2007

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A risk-based bioanalytical strategy for the assessment of antibody immune responses against biological drugs.
Gopi Shankar, Charles Pendley, Kathryn E Stein

Nat Biotechnol· May 2007

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A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis.
Alice B Gottlieb, Kevin D Cooper, Thomas S McCormick, Eiko Toichi, Daniel E Everitt, Charles E Pendley

Curr Med Res Opin· May 2007

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Modulation of CLA, IL-12R, CD40L, and IL-2Ralpha expression and inhibition of IL-12- and IL-23-induced cytokine secretion by CNTO 1275.
Manjula Reddy, Cuc Davis, Jackson Wong, Paul Marsters, Charles Pendley

Cell Immunol· May 2007

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Pharmacokinetics and safety of golimumab, a fully human anti-TNF-alpha monoclonal antibody, in subjects with rheumatoid arthritis.
Honghui Zhou, Haishan Jang, Roy M Fleischmann, Esther Bouman-Thio, Zhenhua Xu, Charles Pendley

J Clin Pharmacol· March 2007

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An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis.
Eiko Toichi, Gisela Torres, Thomas S McCormick, Timothy Chang, Mary Ann Mascelli, Charles E Pendley

J Immunol· October 2006

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A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis.
Catharine L Kauffman, Nancy Aria, Eiko Toichi, Thomas S McCormick, Kevin D Cooper, Charles E Pendley

J Invest Dermatol· December 2004

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Validation and comparative analysis of a multiplexed assay for the simultaneous quantitative measurement of Th1/Th2 cytokines in human serum and human peripheral blood mononuclear cell culture supernatants.
Uma Prabhakar, Edward Eirikis, Manjula Reddy, Eva Silvestro, Susan Spitz, Charles Pendley

J Immunol Methods· August 2004

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Immunogenicity of therapeutic monoclonal antibodies.
Charles Pendley, Allen Schantz, Carrie Wagner

Curr Opin Mol Ther· April 2003

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