Publications by authors named "Charles Stankovic"

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Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, part I: transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors.
Mark S Plummer, Joseph Cornicelli, Howard Roark, Donald J Skalitzky, Charles J Stankovic

Bioorg Med Chem Lett· June 2013

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Discovery of potent selective bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model. Part II: optimization studies and demonstration of in vivo efficacy.
Mark S Plummer, Joseph Cornicelli, Howard Roark, Donald J Skalitzky, Charles J Stankovic

Bioorg Med Chem Lett· June 2013

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Succinic acid amides as P2-P3 replacements for inhibitors of interleukin-1beta converting enzyme (ICE or caspase 1).
Paul Galatsis, Bradley Caprathe, John Gilmore, Anthony Thomas, Kristin Linn, Charles Stankovic

Bioorg Med Chem Lett· September 2010

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The development and validation of a computational model to predict rat liver microsomal clearance.
Cheng Chang, David B Duignan, Kjell D Johnson, Pil H Lee, George S Cowan, Charles J Stankovic

J Pharm Sci· August 2009

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A novel method for assessing inhibition of ibuprofen chiral inversion and its application in drug discovery.
Anita Reddy, Muhammed Hashim, Ziqiang Wang, Lara Penn, Charles J Stankovic

Int J Pharm· April 2007

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Evaluation of an integrated in vitro-in silico PBPK (physiologically based pharmacokinetic) model to provide estimates of human bioavailability.
Hongliang Cai, Chad Stoner, Anita Reddy, Sascha Freiwald, Danielle Smith, Charles Stankovic

Int J Pharm· February 2006

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Implementation of an ADME enabling selection and visualization tool for drug discovery.
Chad L Stoner, Eric Gifford, Charles Stankovic, Christopher S Lepsy, Joanne Brodfuehrer

J Pharm Sci· May 2004

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