Publications by authors named "Charles Timchalk"

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Physiologically Based Pharmacokinetic Modeling of Salivary Concentrations for Noninvasive Biomonitoring of 2,4-Dichlorophenoxyacetic Acid (2,4-D).
Alice A Han, Charles Timchalk, Zana A Carver, Thomas J Weber, Kimberly J Tyrrell

Toxicol Sci· December 2019

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Stable Acinar Progenitor Cell Model Identifies Treacle-Dependent Radioresistance.
Thomas J Weber, Wei-Jun Qian, Jordan N Smith, Marina A Gritsenko, Dehong Hu, Charles Timchalk

Radiat Res· August 2019

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Selective capture of radionuclides (U, Pu, Th, Am and Co) using functional nanoporous sorbents.
Wassana Yantasee, Glen E Fryxell, Kanda Pattamakomsan, Thanapon Sangvanich, Robert J Wiacek, Charles Timchalk

J Hazard Mater· March 2019

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Evaluation of non-invasive biomonitoring of 2,4-Dichlorophenoxyacetic acid (2,4-D) in saliva.
Zana A Carver, Alice A Han, Charles Timchalk, Thomas J Weber, Kimberly J Tyrrell

Toxicology· December 2018

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A 3D-Printed, Portable, Optical-Sensing Platform for Smartphones Capable of Detecting the Herbicide 2,4-Dichlorophenoxyacetic Acid.
Yijia Wang, Mohamed M A Zeinhom, Mingming Yang, Rongrong Sun, Shengfu Wang, Charles Timchalk

Anal Chem· September 2017

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Use of a probabilistic PBPK/PD model to calculate Data Derived Extrapolation Factors for chlorpyrifos.
Torka S Poet, Charles Timchalk, Michael J Bartels, Jordan N Smith, Robin McDougal

Regul Toxicol Pharmacol· June 2017

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Predicting Transport of 3,5,6-Trichloro-2-Pyridinol Into Saliva Using a Combination Experimental and Computational Approach.
Jordan Ned Smith, Zana A Carver, Thomas J Weber, Charles Timchalk

Toxicol Sci· June 2017

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The need for non- or minimally-invasive biomonitoring strategies and the development of pharmacokinetic/pharmacodynamic models for quantification.
Charles Timchalk, Thomas J Weber, Jordan N Smith

Curr Opin Toxicol· June 2017

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Non-invasive saliva human biomonitoring: development of an in vitro platform.
Thomas J Weber, Jordan N Smith, Zana A Carver, Charles Timchalk

J Expo Sci Environ Epidemiol· January 2017

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Comparative Risks of Aldehyde Constituents in Cigarette Smoke Using Transient Computational Fluid Dynamics/Physiologically Based Pharmacokinetic Models of the Rat and Human Respiratory Tracts.
Richard A Corley, Senthil Kabilan, Andrew P Kuprat, James P Carson, Richard E Jacob, Charles Timchalk

Toxicol Sci· July 2015

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Computational strategy for quantifying human pesticide exposure based upon a saliva measurement.
Charles Timchalk, Thomas J Weber, Jordan N Smith

Front Pharmacol· June 2015

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Chlorpyrifos PBPK/PD model for multiple routes of exposure.
Torka S Poet, Charles Timchalk, Jon A Hotchkiss, Michael J Bartels

Xenobiotica· October 2014

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A human life-stage physiologically based pharmacokinetic and pharmacodynamic model for chlorpyrifos: development and validation.
Jordan Ned Smith, Paul M Hinderliter, Charles Timchalk, Michael J Bartels, Torka S Poet

Regul Toxicol Pharmacol· August 2014

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Direct analysis of trichloropyridinol in human saliva using an Au nanoparticles-based immunochromatographic test strip for biomonitoring of exposure to chlorpyrifos.
Weiying Zhang, Yong Tang, Dan Du, Jordan Smith, Charles Timchalk

Talanta· September 2013

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A multi-route model of nicotine-cotinine pharmacokinetics, pharmacodynamics and brain nicotinic acetylcholine receptor binding in humans.
Justin G Teeguarden, Conrad J Housand, Jordan N Smith, Paul M Hinderliter, Rudy Gunawan, Charles A Timchalk

Regul Toxicol Pharmacol· February 2013

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Imaging nicotine in rat brain tissue by use of nanospray desorption electrospray ionization mass spectrometry.
Ingela Lanekoff, Mathew Thomas, James P Carson, Jordan N Smith, Charles Timchalk

Anal Chem· January 2013

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Pharmacokinetics and pharmacodynamics of chlorpyrifos and 3,5,6-trichloro-2-pyridinol in rat saliva after chlorpyrifos administration.
Jordan Ned Smith, Jun Wang, Yuehe Lin, Elise M Klohe, Charles Timchalk

Toxicol Sci· December 2012

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Comparative computational modeling of airflows and vapor dosimetry in the respiratory tracts of rat, monkey, and human.
Richard A Corley, Senthil Kabilan, Andrew P Kuprat, James P Carson, Kevin R Minard, Charles Timchalk

Toxicol Sci· August 2012

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Application of a source-to-outcome model for the assessment of health impacts from dietary exposures to insecticide residues.
Paul S Price, Karl D Schnelle, Cheryl B Cleveland, Michael J Bartels, Paul M Hinderliter, Charles Timchalk

Regul Toxicol Pharmacol· October 2011

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Development of a source-to-outcome model for dietary exposures to insecticide residues: an example using chlorpyrifos.
Paul M Hinderliter, Paul S Price, Michael J Bartels, Charles Timchalk, Torka S Poet

Regul Toxicol Pharmacol· October 2011

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In vitro age-dependent enzymatic metabolism of chlorpyrifos and chlorpyrifos-oxon in human hepatic microsomes and chlorpyrifos-oxon in plasma.
Jordan Ned Smith, Charles Timchalk, Michael J Bartels, Torka S Poet

Drug Metab Dispos· August 2011

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Magnetic electrochemical sensing platform for biomonitoring of exposure to organophosphorus pesticides and nerve agents based on simultaneous measurement of total enzyme amount and enzyme activity.
Dan Du, Jun Wang, Limin Wang, Donglai Lu, Jordan N Smith, Charles Timchalk

Anal Chem· May 2011

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Enzyme-linked immunosorbent assay for detection of organophosphorylated butyrylcholinesterase: a biomarker of exposure to organophosphate agents.
Limin Wang, Dan Du, Donglai Lu, Chiann-Tso Lin, Jordan N Smith, Charles Timchalk

Anal Chim Acta· May 2011

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A novel immunochromatographic electrochemical biosensor for highly sensitive and selective detection of trichloropyridinol, a biomarker of exposure to chlorpyrifos.
Limin Wang, Donglai Lu, Jun Wang, Dan Du, Zhexiang Zou, Charles Timchalk

Biosens Bioelectron· February 2011

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Functionalized nanoporous silica for the removal of heavy metals from biological systems: adsorption and application.
Wassana Yantasee, Ryan D Rutledge, Wilaiwan Chouyyok, Vichaya Sukwarotwat, Galya Orr, Charles Timchalk

ACS Appl Mater Interfaces· October 2010

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