Publications by authors named "Charlie Ly"

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The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and aurora kinases.
Guopan Yu, Weiguo Zhang, Mahesh Basyal, Yuki Nishida, Hideaki Mizumo, Charlie Ly

Leuk Lymphoma· November 2024

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Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy.
Weiguo Zhang, Guopan Yu, Hongying Zhang, Mahesh Basyal, Charlie Ly

Haematologica· June 2023

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FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in AML.
Yannan Jia, Weiguo Zhang, Mahesh Basyal, Kyung Hee Chang, Lauren Ostermann, Charlie Ly

Leukemia· June 2023

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The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and Aurora kinases.
Guopan Yu, Weiguo Zhang, Hongying Zhang, Charlie Ly, Mahesh Basyal

Res Sq· February 2023

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High-throughput proteomic profiling reveals mechanisms of action of AMG925, a dual FLT3-CDK4/6 kinase inhibitor targeting AML and AML stem/progenitor cells.
Zhihong Zeng, Charlie Ly, Naval Daver, Jorge Cortes, Hagop M Kantarjian

Ann Hematol· June 2021

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Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in -mutated acute myeloid leukemias: from concept to clinical trial.
Weiguo Zhang, Charlie Ly, Jo Ishizawa, Hong Mu, Vivian Ruvolo

Haematologica· October 2018

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