Publications by authors named "Chase Cockrell"

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Immune digital twins for complex human pathologies: applications, limitations, and challenges.
Anna Niarakis, Reinhard Laubenbacher, Gary An, Yaron Ilan, Jasmin Fisher, Chase Cockrell

NPJ Syst Biol Appl· November 2024

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A design specification for Critical Illness Digital Twins (CIDTs) to cure sepsis: responding to the National Academies of Sciences, Engineering and Medicine Report "Foundational Research Gaps and Future Directions for Digital Twins".
Gary An, Chase Cockrell

ArXiv· June 2024

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The Wound Environment Agent-based Model (WEABM): a digital twin platform for characterization and complex therapeutic discovery for volumetric muscle loss.
Chase Cockrell, Yoram Vodovotz, Ruben Zamora, Gary An

bioRxiv· June 2024

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Examining B-cell dynamics and responsiveness in different inflammatory milieus using an agent-based model.
Bryan Shin, Gary An, R Chase Cockrell

PLoS Comput Biol· January 2024

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Children are small adults (when properly normalized): Transferrable/generalizable sepsis prediction.
Caitlin Marassi, Damien Socia, Dale Larie, Gary An, R Chase Cockrell

Surg Open Sci· December 2023

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Artificial Intelligence Optical Biopsy for Evaluating the Functional State of Wounds.
Joe Teague, Damien Socia, Gary An, Stephen Badylak, Scott Johnson, R Chase Cockrell

J Surg Res· November 2023

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Characterizing the Crosstalk Between Programmed Cell Death Pathways in Cytokine Storm With an Agent-Based Model.
Solomon Feuerwerker, R Chase Cockrell, Gary An

Surg Infect (Larchmt)· October 2023

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Generating synthetic multidimensional molecular time series data for machine learning: considerations.
Gary An, Chase Cockrell

Front Syst Biol· July 2023

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A Virtual Reading Center Model Using Crowdsourcing to Grade Photographs for Trachoma: Validation Study.
Christopher J Brady, R Chase Cockrell, Lindsay R Aldrich, Meraf A Wolle, Sheila K West

J Med Internet Res· April 2023

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Combination Chemotherapy of Multidrug-resistant Early-stage Colon Cancer: Determining Optimal Dose Schedules by High-performance Computer Simulation.
Chase Cockrell, David E Axelrod

Cancer Res Commun· January 2023

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Prediction of Long COVID Based on Severity of Initial COVID-19 Infection: Differences in predictive feature sets between hospitalized versus non-hospitalized index infections.
Damien Socia, Dale Larie, Sol Feuerwerker, Gary An, Chase Cockrell

medRxiv· January 2023

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Transcriptomic, Proteomic, and Morphologic Characterization of Healing in Volumetric Muscle Loss.
Raphael J Crum, Scott A Johnson, Peng Jiang, Jayati H Jui, Ruben Zamora, Chase Cockrell

Tissue Eng Part A· December 2022

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Detection of trachoma using machine learning approaches.
Damien Socia, Christopher J Brady, Sheila K West, R Chase Cockrell

PLoS Negl Trop Dis· December 2022

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Preparing for the next pandemic: Simulation-based deep reinforcement learning to discover and test multimodal control of systemic inflammation using repurposed immunomodulatory agents.
Chase Cockrell, Dale Larie, Gary An

Front Immunol· December 2022

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Drug Development Digital Twins for Drug Discovery, Testing and Repurposing: A Schema for Requirements and Development.
Gary An, Chase Cockrell

Front Syst Biol· June 2022

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Optical Biopsy Using a Neural Network to Predict Gene Expression From Photos of Wounds.
Grant Schumaker, Andrew Becker, Gary An, Stephen Badylak, Scott Johnson, R Chase Cockrell

J Surg Res· February 2022

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Preparing for the next COVID: Deep Reinforcement Learning trained Artificial Intelligence discovery of multi-modal immunomodulatory control of systemic inflammation in the absence of effective anti-microbials.
Dale Larie, Gary An, Chase Cockrell

bioRxiv· February 2022

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Iterative community-driven development of a SARS-CoV-2 tissue simulator.
Michael Getz, Yafei Wang, Gary An, Maansi Asthana, Andrew Becker, Chase Cockrell

bioRxiv· November 2021

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The Use of Artificial Neural Networks to Forecast the Behavior of Agent-Based Models of Pathophysiology: An Example Utilizing an Agent-Based Model of Sepsis.
Dale Larie, Gary An, R Chase Cockrell

Front Physiol· October 2021

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Agent-Based Modeling of Systemic Inflammation: A Pathway Toward Controlling Sepsis.
Gary An, R Chase Cockrell

Methods Mol Biol· August 2021

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Comparative Computational Modeling of the Bat and Human Immune Response to Viral Infection with the Comparative Biology Immune Agent Based Model.
Chase Cockrell, Gary An

Viruses· August 2021

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Utilizing the Heterogeneity of Clinical Data for Model Refinement and Rule Discovery Through the Application of Genetic Algorithms to Calibrate a High-Dimensional Agent-Based Model of Systemic Inflammation.
Chase Cockrell, Gary An

Front Physiol· May 2021

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Nested active learning for efficient model contextualization and parameterization: pathway to generating simulated populations using multi-scale computational models.
Chase Cockrell, Jonathan Ozik, Nick Collier, Gary An

Simulation· April 2021

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Prevention of Colon Cancer Recurrence From Minimal Residual Disease: Computer Optimized Dose Schedules of Intermittent Apoptotic Adjuvant Therapy.
Chase Cockrell, Joseph Teague, David E Axelrod

JCO Clin Cancer Inform· June 2020

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Inflammation and Disease: Modelling and Modulation of the Inflammatory Response to Alleviate Critical Illness.
Judy D Day, Chase Cockrell, Rami Namas, Ruben Zamora, Gary An

Curr Opin Syst Biol· December 2018

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