Publications by authors named "Chelliah Selvam"

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Targeting Poly (ADP-Ribose) Polymerase-1 for the Treatment of Neurodegenerative Diseases.
Shahrazad Polk, Mana Rassaeikashuk, Ramasamy Thilagavathi, Chelliah Selvam

Chem Biol Drug Des· November 2025

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Discovery of a novel STAT3 inhibitor: A potential application for pancreatic cancer treatment.
Xiaoyu Yang, Chia-Nung Hung, Meagan Ybarra, Michelle Villarreal, Pawel Osmulski, Chelliah Selvam

Biomed Pharmacother· October 2025

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Functionalized Nanoparticles: A Promising Approach for Effective Management of Alzheimer's Disease.
Subhasri Bogadi, Mahendran Bhaskaran, Vishnuvardh Ravichandran, Jerry Nesamony, Selvam Chelliah

Mol Neurobiol· August 2025

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Development and application of LC-MS/MS method for the quantification of hydrogen sulfide in the eye.
Anthonia Okolie, Maria Rincon Nigro, Sharhazad Polk, Keyona Stubbs, Selvam Chelliah

Anal Biochem· April 2024

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Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia.
Pavan Kumar Chintamaneni, Sai Kiran S S Pindiprolu, Swati Swagatika Swain, Veera Venkata Satyanarayana Reddy Karri, Jerry Nesamony, Selvam Chelliah

Cancer Lett· April 2024

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Dual Anti-Inflammatory and Anticancer Activity of Novel 1,5-Diaryl Pyrazole Derivatives: Molecular Modeling, Synthesis, In Vitro Activity, and Dynamics Study.
Priya Deivasigamani, S M Esther Rubavathy, Narayanan Jayasankar, Venkatesan Saravanan, Ramasamy Thilagavathi, Chelliah Selvam

Biomedicines· April 2024

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Identification of indole-based natural compounds as inhibitors of PARP-1 against triple-negative breast cancer: a computational study.
Sridhar Priyankha, Varatharaj Rajapandian, Kandhan Palanisamy, S M Esther Rubavathy, Ramasamy Thilagavathi, Chelliah Selvam

J Biomol Struct Dyn· March 2024

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Discovery of novel HDAC8 inhibitors from natural compounds by in silico high throughput screening.
S M Esther Rubavathy, Kandhan Palanisamy, S Priyankha, Ramasamy Thilagavathi, Muthuramalingam Prakash, Chelliah Selvam

J Biomol Struct Dyn· November 2023

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Recent insights into the hepatoprotective potential of medicinal plants and plant-derived compounds.
Ramasamy Thilagavathi, S Sameema Begum, Sowfika Dharshini Varatharaj, Arun Kumar Balasubramaniam, Joselin Susan George, Chelliah Selvam

Phytother Res· May 2023

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Compounds from diverse natural origin against triple-negative breast cancer: A comprehensive review.
Ramasamy Thilagavathi, Sridhar Priyankha, Manivel Kannan, Muthuramalingam Prakash, Chelliah Selvam

Chem Biol Drug Des· January 2023

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A comprehensive review on glucokinase activators: Promising agents for the treatment of Type 2 diabetes.
Ramasamy Thilagavathi, Maryam Sadat Hosseini-Zare, Manokaran Malini, Chelliah Selvam

Chem Biol Drug Des· February 2022

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Antiviral activities of natural compounds and ionic liquids to inhibit the Mpro of SARS-CoV-2: a computational approach.
Kandhan Palanisamy, S M Esther Rubavathy, Muthuramalingam Prakash, Ramasamy Thilagavathi, Maryam S Hosseini-Zare, Chelliah Selvam

RSC Adv· January 2022

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Methods of hexagonal boron nitride exfoliation and its functionalization: covalent and non-covalent approaches.
Chandkiram Gautam, Selvam Chelliah

RSC Adv· September 2021

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Synergistic effects of curcumin and its analogs with other bioactive compounds: A comprehensive review.
Maryam Sadat Hosseini-Zare, Mozhgan Sarhadi, Mehdi Zarei, Ramasamy Thilagavathi, Chelliah Selvam

Eur J Med Chem· January 2021

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Histone Deacetylase Inhibitors as Multitarget-Directed Epi-Drugs in Blocking PI3K Oncogenic Signaling: A Polypharmacology Approach.
Kasturi Ranganna, Chelliah Selvam, Amruthesh Shivachar, Zivar Yousefipour

Int J Mol Sci· November 2020

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Discovery of Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Inhibitors by Ligand-based Virtual High Throughput Screening.
Chelliah Selvam, Charlotta D Mock, Omana P Mathew, Kasturi Ranganna, Ramasamy Thilagavathi

Mol Inform· July 2020

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Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review.
Maryam S Hosseini-Zare, Ramasamy Thilagavathi, Chelliah Selvam

RSC Adv· July 2020

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Molecular mechanisms of curcumin and its analogs in colon cancer prevention and treatment.
Chelliah Selvam, Sakthivel Lakshmana Prabu, Brian C Jordan, Yasodha Purushothaman, Appavoo Umamaheswari

Life Sci· December 2019

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Cellular Effects of Butyrate on Vascular Smooth Muscle Cells are Mediated through Disparate Actions on Dual Targets, Histone Deacetylase (HDAC) Activity and PI3K/Akt Signaling Network.
Omana P Mathew, Kasturi Ranganna, Joseph Mathew, Meiling Zhu, Zivar Yousefipour, Chelliah Selvam

Int J Mol Sci· June 2019

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Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites.
Chelliah Selvam, Isabelle A Lemasson, Isabelle Brabet, Nadia Oueslati, Berin Karaman

J Med Chem· March 2018

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Synthesis, evaluation of cytotoxic properties of promising curcumin analogues and investigation of possible molecular mechanisms.
Brian C Jordan, Bhavna Kumar, Ramasamy Thilagavathi, Arti Yadhav, Pawan Kumar, Chelliah Selvam

Chem Biol Drug Des· January 2018

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Therapeutic potential of chemically modified siRNA: Recent trends.
Chelliah Selvam, Daniel Mutisya, Sandhya Prakash, Kasturi Ranganna, Ramasamy Thilagavathi

Chem Biol Drug Des· November 2017

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Pterocarpan scaffold: A natural lead molecule with diverse pharmacological properties.
Chelliah Selvam, Brian C Jordan, Sandhya Prakash, Daniel Mutisya, Ramasamy Thilagavathi

Eur J Med Chem· March 2017

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Molecular mechanisms of curcumin and its semisynthetic analogues in prostate cancer prevention and treatment.
Brian C Jordan, Charlotta D Mock, Ramasamy Thilagavathi, Chelliah Selvam

Life Sci· May 2016

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Computer-aided design of negative allosteric modulators of metabotropic glutamate receptor 5 (mGluR5): Comparative molecular field analysis of aryl ether derivatives.
Chelliah Selvam, Ramasamy Thilagavathi, Balasubramanian Narasimhan, Pradeep Kumar, Brian C Jordan

Bioorg Med Chem Lett· February 2016

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