Publications by authors named "Cheng Cheung Chen"

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Targeting SARS-CoV-2 RNA-dependent RNA polymerase with the coumarin derivative BPR2-D2: Evidence from cell-based and enzymatic studies.
Wen-Fang Tang, Hui-Ping Tsai, Yuan-Fan Chin, Shan-Ko Tsai, Cheng-Chin Lin, Yu-Li Chen, Yuan-Siao Chen, Ping-Cheng Liu, Cheng Cheung Chen, Shu-Chen Hsu

Biomed Pharmacother· August 2025

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Enhancing the in vivo efficacy of anthrax vaccine using trimethylchitosan covalently coated chitosomes in a single-step microfluidic synthesis.
Chuan-Chung Chuang, Cheng-Cheung Chen, Xin-An Chen, Chia-Ying Lee, Yu-Hsiu Chang

Int J Biol Macromol· April 2025

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Reverse transcription-quantitative PCR assays for detecting SARS-CoV-2 using subgenomic RNA load.
Yun-Hsiang Cheng, Cheng-Hsiu Chen, Ping-Cheng Liu, Wen-Ting Chen, Chi-Ju Hsu, Cheng-Cheung Chen

Heliyon· February 2025

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Synergistic antiviral potential of N-(2-hydroxy)propyl-3-trimethylammoniumchitosan-functionalized silver nanoparticles with oseltamivir against influenza A viruses.
Ping-Cheng Liu, Tein-Yao Chang, Xin-An Chen, Chih-Chia Cheng, Chih-Heng Huang, An-Yu Chen, Cheng-Cheung Chen

Int J Biol Macromol· January 2025

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Polyelectrolyte-coated liposomes microfluidically assembled in one-step for enhancing cell endocytosis and in-vivo immune responses.
Xin-An Chen, Chuan-Chang Chuang, Cheng-Cheung Chen, Chia-Ying Lee, Chia-Ying Chin

Colloids Surf B Biointerfaces· September 2024

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Functional and structural investigation of a broadly neutralizing SARS-CoV-2 antibody.
Yi-Hsuan Chang, Min-Feng Hsu, Wei-Nan Chen, Min-Hao Wu, Wye-Lup Kong, An-Yu Chen, Cheng-Cheung Chen, Yi-Hua Chen

JCI Insight· May 2024

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Simultaneous detection of SARS-CoV-2 S1 protein by using flexible electrochemical and Raman enhancing biochip.
Kuan-Syun Wang, Tsai-Yu Kuan, Yun-Chu Chen, Yu-Ju Chu, Jeng-Shiung Chen, Cheng-Cheung Chen

Biosens Bioelectron· April 2024

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BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir.
Wen-Fang Tang, Yu-Hsiu Chang, Cheng-Chin Lin, Jia-Rong Jheng, Chung-Fan Hsieh, Yu-Li Chen, Yuan-Siao Chen, Ping-Cheng Liu, Cheng Cheung Chen

Antimicrob Agents Chemother· April 2024

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Reproducible SERS substrates manipulated by interparticle spacing and particle diameter of gold nano-island array using in-situ thermal evaporation.
Ming-Chien Yang, Ting-Yin Chien, Yu-Wei Cheng, Chien-Kuo Hsieh, Wei-Lin Syu, Yun-Chu Chen, Jeng-Shiung Chen, Cheng-Cheung Chen

Spectrochim Acta A Mol Biomol Spectrosc· December 2023

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Development of AAV-delivered broadly neutralizing anti-human ACE2 antibodies against SARS-CoV-2 variants.
Cheng-Pu Sun, Chi-Wen Chiu, Ping-Yi Wu, Szu-I Tsung, I-Jung Lee, Li-Yao Chen, Yung-Jiun Chen, Cheng-Cheung Chen, Yen-Hui Chen

Mol Ther· November 2023

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Development of an EBOV MiniG plus system as an advanced tool for anti-Ebola virus drug screening.
Chi-Ju Hsu, Cheng-Hsiu Chen, Wen-Ting Chen, Ping-Cheng Liu, Tein-Yao Chang, Cheng-Cheung Chen, Hsing-Yu Chen, Yun-Hsiang Cheng

Heliyon· November 2023

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Employing functionalized graphene quantum dots to combat coronavirus and enterovirus.
Chien-Te Hsieh, Siyong Gu, Yasser Ashraf Gandomi, Chun-Chieh Fu, Po-Yu Sung, Cheng-Cheung Chen

J Colloid Interface Sci· January 2023

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Immunoglobulin Y Specific for SARS-CoV-2 Spike Protein Subunits Effectively Neutralizes SARS-CoV-2 Infectivity and Ameliorates Disease Manifestations In Vivo.
Chia-Tsui Yeh, Chia-Ying Lee, Yi-Jung Ho, Sin-An Chen, Liang-Yu Chen, Ping-Cheng Liu, An-Yu Chen, Cheng-Cheung Chen

Biomedicines· November 2022

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Orally delivered perilla (Perilla frutescens) leaf extract effectively inhibits SARS-CoV-2 infection in a Syrian hamster model.
Yuan-Fan Chin, Wen-Fan Tang, Yu-Hsiu Chang, Tein-Yao Chang, Wen-Chin Lin, Ping-Cheng Liu, Shu-Chen Hsu, Cheng Cheung Chen, Cheng-Hsun Chiu

J Food Drug Anal· June 2022

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Replica of Bionic Nepenthes Peristome-like and Anti-Fouling Structures for Self-Driving Water and Raman-Enhancing Detection.
Yen-Ting Lin, Chun-Hao Wu, Wei-Lin Syu, Po-Cheng Ho, Zi-Ling Tseng, Cheng-Chen Chen, Cheng-Cheung Chen

Polymers (Basel)· June 2022

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Ser253Leu substitution in PmrB contributes to colistin resistance in clinical .
Ya-Sung Yang, Wen-Yih Jeng, Yi-Tzu Lee, Chi-Ju Hsu, Yu-Ching Chou, Shu-Chen Kuo, Cheng-Cheung Chen, Hsing-Yu Chen

Emerg Microbes Infect· December 2021

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Nanoparticular CpG-adjuvanted SARS-CoV-2 S1 protein elicits broadly neutralizing and Th1-biased immunoreactivity in mice.
Hui-Tsu Lin, Cheng-Cheung Chen, Der-Jiang Chiao, Tein-Yao Chang, Xin-An Chen, Szu-Cheng Kuo

Int J Biol Macromol· December 2021

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Alginate-Capped Silver Nanoparticles as a Potent Anti-mycobacterial Agent Against .
Cheng-Cheung Chen, Yih-Yuan Chen, Chang-Ching Yeh, Chia-Wei Hsu, Shang-Jie Yu, Xin-An Chen

Front Pharmacol· November 2021

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Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation.
Wen-Fang Tang, Hui-Ping Tsai, Yu-Hsiu Chang, Tein-Yao Chang, Chung-Fan Hsieh, Yu-Li Chen, Ping-Cheng Liu, Cheng Cheung Chen

Biomed J· June 2021

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E3 ubiquitin ligase Grail promotes hepatic steatosis through Sirt1 inhibition.
Pei-Yao Liu, Cheng-Cheung Chen, Chia-Ying Chin, Te-Jung Liu, Wen-Chiuan Tsai, Yu-Guang Chen, Ying-Chuan Chen

Cell Death Dis· March 2021

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Nanoparticles assembled from fucoidan and trimethylchitosan as anthrax vaccine adjuvant: In vitro and in vivo efficacy in comparison to CpG.
Meng-Hung Tsai, Chuan-Chang Chuang, Cheng-Cheung Chen, Hui-Ju Yen, Kuang-Ming Cheng, Xin-An Chen

Carbohydr Polym· May 2020

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A fucoidan-quaternary chitosan nanoparticle adjuvant for anthrax vaccine as an alternative to CpG oligodeoxynucleotides.
Chuan-Chang Chuang, Meng-Hung Tsai, Hui-Ju Yen, Huey-Fen Shyu, Kuang-Ming Cheng, Xin-An Chen, Cheng-Cheung Chen

Carbohydr Polym· February 2020

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Fungicidal and anti-biofilm activities of trimethylchitosan-stabilized silver nanoparticles against Candida species in zebrafish embryos.
Shao-Hung Wang, Cheng-Cheung Chen, Chih-Hua Lee, Xin-An Chen, Tein-Yao Chang, Yi-Chuan Cheng

Int J Biol Macromol· January 2020

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Grail attenuates influenza A virus infection and pathogenesis by inhibiting viral nucleoprotein.
Hui-Tsu Lin, Cheng-Cheung Chen, Pei-Yao Liu, Hsueh-Ling Wu, Ti-Hui Wu, Ying-Chuan Chen

Sci Rep· November 2018

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Positively charged gold nanoparticles capped with folate quaternary chitosan: Synthesis, cytotoxicity, and uptake by cancer cells.
Hui-Ju Yen, Yen-An Young, Tsung-Neng Tsai, Kuang-Ming Cheng, Xin-An Chen, Ying-Chuan Chen, Cheng-Cheung Chen

Carbohydr Polym· March 2018

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