Publications by authors named "Cheng E Chee"

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Effects of current smoking on treatment outcomes in metastatic and locally advanced pancreatic carcinoma: a retrospective cohort study using the international PURPLE pancreas cancer registry.
Faisal Hayat, Simon Chiu, Ashleigh Stuart, Belinda Lee, Peter Gibbs, Cheng Ean Chee

J Gastrointest Oncol· October 2025

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Functional Precision in Pancreatic Cancer: Redefining Biomarkers with Patient-Derived Organoids.
Claire Alexandra Chew, Cheng Mun Wun, Yi Fang Lee, Cheng Ean Chee, Khek Yu Ho

Int J Mol Sci· September 2025

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Charting New Paths in Cancer Research: Insights from the Frontiers in Cancer Science Conference 2024.
Giang Le Minh, Sasidharan Swarnalatha Lucky, Shazib Pervaiz, Kristijan Ramadan, Joe Yeong, Cheng Ean Chee

Cancer Res· August 2025

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NEXUS: a phase I dose escalation study of selinexor plus nivolumab and ipilimumab in Asian patients with advanced/metastatic solid malignancies.
Joan R Choo, Santhiay Nathan Jeraj, Raghav Sundar, Wei Peng Yong, Matilda Lee, Cheng Ean Chee

Ther Adv Med Oncol· June 2025

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TIMEPOINT, a phase 1 study combining MTL-CEBPA with pembrolizumab, supports the immunomodulatory effect of MTL-CEBPA in solid tumors.
Ruth Plummer, Mikael H Sodergren, Rose Hodgson, Bríd M Ryan, Nina Raulf, Cheng E Chee

Cell Rep Med· April 2025

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Personalized dose selection platform for patients with solid tumors in the PRECISE CURATE.AI feasibility trial.
Agata Blasiak, Anh T L Truong, Nigel Foo, Lester W J Tan, Kirthika S Kumar, Cheng Ean Chee

NPJ Precis Oncol· February 2025

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State-of-the-Art Management of Colorectal Cancer: Treatment Advances and Innovation.
Priyadarshini S Pathak, Gloria Chan, Dustin A Deming, Cheng Ean Chee

Am Soc Clin Oncol Educ Book· June 2024

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Cost-effectiveness analysis of atezolizumab plus bevacizumab compared with sorafenib as first-line treatment in advanced hepatocellular carcinoma in Singapore.
Cheng Ean Chee, Jasmeet Singh Khara, John Cheong, Jek Fong, Sivabalan Sivanesan

Expert Rev Pharmacoecon Outcomes Res· June 2024

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Early onset pancreatic cancer-exploring contemporary treatment and outcomes using real-world data.
Shehara Mendis, Lara Lipton, Yat Hang To, Sumitra Ananda, Michael Michael, Cheng Ean Chee

Br J Cancer· May 2024

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Molecular profiling of metastatic breast cancer and target-based therapeutic matching in an Asian tertiary phase I oncology unit.
Robert John Walsh, Rebecca Ong, Seng Wee Cheo, Peter Q J Low, Aishwarya Jayagopal, Cheng Ean Chee

Front Oncol· May 2024

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Current advances in targeted therapy for metastatic colorectal cancer - Clinical translation and future directions.
David Johnson, Cheng Ean Chee, Wesley Wong, Rachel C T Lam, Iain Bee Huat Tan

Cancer Treat Rev· April 2024

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Updated efficacy and safety of entrectinib in NTRK fusion-positive non-small cell lung cancer.
Byoung Chul Cho, Chao-Hua Chiu, Erminia Massarelli, Gary L Buchschacher, Koichi Goto, Cheng E Chee

Lung Cancer· February 2024

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Reducing Chemotherapy Waiting Times in the Ambulatory Setting of a Tertiary Cancer Centre Using a Design Thinking Approach.
Wei-Ying Jen, Zhi Yao Chan, Yee Mei Lee, Noel Ng, Belinda Tan, Cheng Ean Chee, Yen-Lin Chee

Cancers (Basel)· September 2023

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Clinical relevance of PD-1 positive CD8 T-cells in gastric cancer.
Joan Choo, Ley Fang Kua, Mu Yar Soe, Bernadette Reyna Asuncion, Benjamin Kye Jyn Tan, Cheng Ean Chee

Gastric Cancer· May 2023

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A Phase I, First-in-Human Study of PRL3-zumab in Advanced, Refractory Solid Tumors and Hematological Malignancies.
Cheng E Chee, Melissa Ooi, Soo-Chin Lee, Raghav Sundar, Valerie Heong

Target Oncol· May 2023

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Clinical outcome and prognostic factors for Asian patients in Phase I clinical trials.
Jerold Loh, Jiaxuan Wu, Jenny Chieng, Aurora Chan, Wei-Peng Yong, Cheng E Chee

Br J Cancer· April 2023

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Circulating Tumor DNA as a Predictive Biomarker for Clinical Outcomes With Margetuximab and Pembrolizumab in Pretreated HER2-Positive Gastric/ Gastroesophageal Adenocarcinoma.
Daniel Vt Catenacci, Yoon-Koo Kang, Hope E Uronis, Keun-Wook Lee, Matthew Ch Ng, Cheng Ean Chee

Oncology (Williston Park)· April 2023

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Use and outcomes from neoadjuvant chemotherapy in borderline resectable pancreatic ductal adenocarcinoma in an Australasian population.
Imogen Walpole, Belinda Lee, Jeremy Shapiro, Benjamin Thomson, Lara Lipton, Cheng Ean Chee

Asia Pac J Clin Oncol· February 2023

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Clinical efficacy and long-term immunogenicity of an early triple dose regimen of SARS-CoV-2 mRNA vaccination in cancer patients.
Matilda Xinwei Lee, Siyu Peng, Ainsley Ryan Yan Bin Lee, Shi Yin Wong, Ryan Yong Kiat Tay, Cheng Ean Chee

Ann Acad Med Singap· January 2023

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Outcomes of a Phase II Study of Intraperitoneal Paclitaxel plus Systemic Capecitabine and Oxaliplatin (XELOX) for Gastric Cancer with Peritoneal Metastases.
Daryl K A Chia, Raghav Sundar, Guowei Kim, Jia Jun Ang, Jeffrey H Y Lum, Cheng Ean Chee

Ann Surg Oncol· December 2022

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Incident Cardiovascular Diseases Among Survivors of High-Risk Stage II-III Colorectal Cancer: A Cluster-Wide Cohort Study.
Shing Fung Lee, Pui Lam Yip, Balamurugan A Vellayappan, Cheng Ean Chee, Lea Choung Wong

J Natl Compr Canc Netw· October 2022

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Rational drug combination design in patient-derived avatars reveals effective inhibition of hepatocellular carcinoma with proteasome and CDK inhibitors.
Jhin Jieh Lim, Lissa Hooi, Yock Young Dan, Glenn K Bonney, Lei Zhou, Cheng Ean Chee

J Exp Clin Cancer Res· August 2022

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Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Postmenopausal Women with Hormone Receptor-Positive Breast Cancer.
Joline S J Lim, Andrea L A Wong, Samuel G W Ow, Natalie Y L Ngoi, Gloria H J Chan, Cheng Ean Chee

Clin Cancer Res· June 2022

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Phase Ib Dose-Finding Study of Varlitinib Combined with Weekly Paclitaxel With or Without Carboplatin ± Trastuzumab in Advanced Solid Tumors.
Matilda Xinwei Lee, Andrea L A Wong, Samuel Ow, Raghav Sundar, David S P Tan, Cheng Ean Chee

Target Oncol· March 2022

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Author Correction: PRL3-zumab as an immunotherapy to inhibit tumors expressing PRL3 oncoprotein.
Min Thura, Abdul Qader Al-Aidaroos, Abhishek Gupta, Cheng Ean Chee, Soo Chin Lee

Nat Commun· November 2021

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