Publications by authors named "Cheng-Ran Xu"

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Hepatocyte metabolic adaptations during pregnancy and lactation.
Li Yang, Yu Zhang, Xin-Xin Yu, Yu-Heng Zhou, Shuang He, Xun-Kai Li, Cheng-Ran Xu

Cell· November 2025

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Reconstructing human pancreatic gene networks enhances stem cell-derived β cell induction.
Xin-Xin Yu, Xin Wang, Liu Yang, Mao-Yang He, Xi Wang, Cheng-Ran Xu

Dev Cell· October 2025

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E- and N-cadherin drive hepatic polarity and lumen elongation via opposing effects on RhoA activity.
Junya Hayase, Li Yang, Yu-Heng Zhou, Kangji Wang, Cheng-Ran Xu

bioRxiv· October 2025

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Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets.
Xin-Xin Yu, Peng Peng, Yi-Ning Wang, Mao-Yang He, Shuang He, Cheng-Ran Xu

Adv Sci (Weinh)· August 2025

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Proenkephalin produced by neonatal T-bet + Treg cells promotes periportal hepatocyte maturation.
Yujia Wang, Lijun Yang, Mingyang Li, Jie Hao, Xiuyuan Sun, Cheng-Ran Xu, Xuyu Zhou

Hepatology· May 2025

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ACSS2 mediates an epigenetic pathway to regulate β-cell adaptation during gestation in mice.
Yu Zhang, Shuang He, Xi Wang, Xin Wang, Mao-Yang He, Cheng-Ran Xu

Nat Commun· May 2025

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The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiation.
Liu Yang, Xin-Xin Yu, Xin Wang, Chen-Tao Jin, Cheng-Ran Xu

Sci Adv· March 2025

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Spatiotemporal and genetic cell lineage tracing of endodermal organogenesis at single-cell resolution.
Ke-Ran Li, Pei-Long Yu, Qi-Qi Zheng, Xin Wang, Xuan Fang, Cheng-Ran Xu

Cell· February 2025

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Determination of key events in mouse hepatocyte maturation at the single-cell level.
Li Yang, Xin Wang, Jia-Xi Zheng, Zi-Ran Xu, Lin-Chen Li, Cheng-Ran Xu

Dev Cell· October 2023

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The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms.
Li Yang, Xin Wang, Xin-Xin Yu, Lu Yang, Bi-Chen Zhou, Cheng-Ran Xu

Dev Cell· September 2023

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EZH2 controls epicardial cell migration during heart development.
Haobin Jiang, Lina Bai, Shen Song, Qianqian Yin, Anteng Shi, Cheng-Ran Xu

Life Sci Alliance· June 2023

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Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics.
Suwei Gao, Qiang Shi, Yifan Zhang, Guixian Liang, Zhixin Kang, Cheng-Ran Xu, Xun Xu

Cell Res· January 2022

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Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans.
Xin-Xin Yu, Wei-Lin Qiu, Liu Yang, Yan-Chun Wang, Mao-Yang He, Cheng-Ran Xu

Cell Res· August 2021

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CCM2L (Cerebral Cavernous Malformation 2 Like) Deletion Aggravates Cerebral Cavernous Malformation Through Map3k3-KLF Signaling Pathway.
Jaesung P Choi, Xi Yang, Shuang He, Renhua Song, Zi-Ran Xu, Cheng-Ran Xu

Stroke· April 2021

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Single-cell patterning and axis characterization in the murine and human definitive endoderm.
Lin-Chen Li, Xin Wang, Zi-Ran Xu, Yan-Chun Wang, Ye Feng, Cheng-Ran Xu

Cell Res· March 2021

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Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level.
Xin Wang, Li Yang, Yan-Chun Wang, Zi-Ran Xu, Ye Feng, Cheng-Ran Xu

Cell Res· December 2020

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Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells.
Sisi Feng, Jiaying Wu, Wei-Lin Qiu, Li Yang, Xiaogang Deng, Zi-Ran Xu, Cheng-Ran Xu

Cell Rep· December 2020

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Characterizing pancreatic β-cell heterogeneity in the streptozotocin model by single-cell transcriptomic analysis.
Ye Feng, Wei-Lin Qiu, Xin-Xin Yu, Yu Zhang, Mao-Yang He, Cheng-Ran Xu

Mol Metab· July 2020

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Understanding generation and regeneration of pancreatic β cells from a single-cell perspective.
Xin-Xin Yu, Cheng-Ran Xu

Development· April 2020

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The contributions of mesoderm-derived cells in liver development.
Li Yang, Lin-Chen Li, Lamaoqiezhong, Xin Wang, Wei-Hua Wang, Cheng-Ran Xu

Semin Cell Dev Biol· August 2019

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Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution.
Xin-Xin Yu, Wei-Lin Qiu, Liu Yang, Yu Zhang, Mao-Yang He, Cheng-Ran Xu

EMBO J· April 2019

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Single-cell transcriptomic analyses reveal distinct dorsal/ventral pancreatic programs.
Lin-Chen Li, Wei-Lin Qiu, Yu-Wei Zhang, Zi-Ran Xu, Yi-Ni Xiao, Cheng-Ran Xu

EMBO Rep· October 2018

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Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells.
Lin-Chen Li, Xin-Xin Yu, Yu-Wei Zhang, Ye Feng, Wei-Lin Qiu, Cheng-Ran Xu

J Vis Exp· September 2018

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Deciphering Pancreatic Islet β Cell and α Cell Maturation Pathways and Characteristic Features at the Single-Cell Level.
Wei-Lin Qiu, Yu-Wei Zhang, Ye Feng, Lin-Chen Li, Liu Yang, Cheng-Ran Xu

Cell Metab· March 2018

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Dynamics of chromatin marks and the role of JMJD3 during pancreatic endocrine cell fate commitment.
Xin-Xin Yu, Wei-Lin Qiu, Liu Yang, Lin-Chen Li, Yu-Wei Zhang, Cheng-Ran Xu

Development· March 2018

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