Publications by authors named "Chengcan Yang"

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Novel missense mutations in the tumor necrosis factor domain of Ectodysplasin-A cause non-syndromic tooth agenesis in two Chinese families.
Chengcan Yang, Nuo Xu, Xiaona Song, Kai Yang, Qian Gao

Arch Oral Biol· January 2026

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Novel SOS1 Mutations Associated With Hereditary Gingival Fibromatosis and Dual-Gated Model for SOS1 Activation.
Qian Gao, Chengcan Yang, Nuo Xu, Xiaona Song, Zhuan Bian, Kai Yang

J Oral Pathol Med· November 2025

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Impact of bariatric surgery on the resolution of obesity hypoventilation syndrome at 1-year follow-up: a retrospective study.
Shuai Ma, Wenwen Yu, Chengcan Yang, Yining He, Dongzi Zhu

J Clin Sleep Med· October 2025

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Sympathetic nerves inhibit dental pulp stem cell differentiation and tertiary dentine formation via α1B-adrenergic receptor.
Chengcan Yang, Qian Gao, Nuo Xu, Xiaona Song, Zhuan Bian, Kai Yang

Int Endod J· October 2025

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A Prediction Model for Obstructive Sleep Apnea in Bariatric Surgery Candidates with Obesity.
Xiaoxiao Zhu, Bei Xu, Chengcan Yang, Shuai Ma, Guihua Hao

Obes Surg· October 2025

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Gut Microbiota-Butyrate-PPARγ Axis Modulates Adipose Regulatory T Cell Population.
Banru Chen, Lizhi Guan, Chao Wu, Yiwen Gong, Lei Wu, Chengcan Yang

Adv Sci (Weinh)· May 2025

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Peripheral Lysosomal Positioning in Inflamed Odontoblasts Facilitates Mineralization.
Nuo Xu, Qian Gao, Chengcan Yang, Xiaona Song, Kai Yang

J Endod· February 2025

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Correction to "Discovery, Synthesis, and Evaluation of Novel Dual Inhibitors of a Vascular Endothelial Growth Factor Receptor and Poly(ADP-Ribose) Polymerase for BRCA Wild-Type Breast Cancer Therapy".
Yang Li, Yun Liu, Dan Zhang, Juncheng Chen, Gaoxia Yang, Chengcan Yang, Liang Ouyang

J Med Chem· February 2025

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Transfusion Thresholds and Risk Factors of Acute Kidney Injury in Gastrointestinal Oncology Surgery: Insights from a Retrospective Study.
Shuai Ma, Qi He, Chengcan Yang, Zhiyuan Zhou, Yining He

Healthcare (Basel)· February 2025

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Concurrent laparoscopic sleeve gastrectomy with uvulopalatopharyngoplasty in the treatment of morbid obesity comorbid with severe obstructive sleep apnea: a retrospective cohort study.
Chengcan Yang, Wenwen Yu, Kan Yao, Yining He, Hongxia Sun

J Clin Sleep Med· April 2024

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Lipid metabolic reprogramming mediated by circulating Nrg4 alleviates metabolic dysfunction-associated steatotic liver disease during the early recovery phase after sleeve gastrectomy.
Chengcan Yang, Dongzi Zhu, Chaofan Liu, Wenyue Wang, Yining He

BMC Med· April 2024

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Human Dental Pulp Stem Cells Are Subjected to Metabolic Reprogramming and Repressed Proliferation and Migration by the Sympathetic Nervous System via α1B-Adrenergic Receptor.
Chengcan Yang, Qian Gao, Nuo Xu, Kai Yang, Zhuan Bian

J Endod· December 2023

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Discovery, Synthesis, and Evaluation of Novel Dual Inhibitors of a Vascular Endothelial Growth Factor Receptor and Poly(ADP-Ribose) Polymerase for BRCA Wild-Type Breast Cancer Therapy.
Yang Li, Yun Liu, Dan Zhang, Juncheng Chen, Gaoxia Yang, Chengcan Yang, Liang Ouyang

J Med Chem· September 2023

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Prognostic Predictors of Endodontic Microsurgery: Radiographic Assessment.
Chaonan Su, Rui Zhang, Rong Wang, Chengcan Yang, Zan Wang

Int Dent J· October 2022

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Protocatechuic Acid-Based Supramolecular Hydrogel Targets SerpinB9 to Achieve Local Chemotherapy for OSCC.
Zaiye Li, Lideng Cao, Chengcan Yang, Tiannan Liu, Hang Zhao

ACS Appl Mater Interfaces· August 2022

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Discovery of 4-Hydroxyquinazoline Derivatives as Small Molecular BET/PARP1 Inhibitors That Induce Defective Homologous Recombination and Lead to Synthetic Lethality for Triple-Negative Breast Cancer Therapy.
Jifa Zhang, Chengcan Yang, Pan Tang, Juncheng Chen, Dan Zhang, Yang Li, Gaoxia Yang, Liang Ouyang

J Med Chem· May 2022

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Targeting Bromodomain-Selective Inhibitors of BET Proteins in Drug Discovery and Development.
Juncheng Chen, Pan Tang, Yuxi Wang, Jiaxing Wang, Chengcan Yang, Yang Li, Gaoxia Yang, Liang Ouyang

J Med Chem· April 2022

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Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models.
Minru Liao, Qiang Xie, Yuqian Zhao, Chengcan Yang, Congcong Lin

Pharmacol Res· February 2022

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Discovery of Novel Dual-Target Inhibitor of Bromodomain-Containing Protein 4/Casein Kinase 2 Inducing Apoptosis and Autophagy-Associated Cell Death for Triple-Negative Breast Cancer Therapy.
Jifa Zhang, Pan Tang, Ling Zou, Jin Zhang, Juncheng Chen, Chengcan Yang, Liang Ouyang

J Med Chem· December 2021

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MCDB: A comprehensive curated mitotic catastrophe database for retrieval, protein sequence alignment, and target prediction.
Le Zhang, Lei Zhang, Yue Guo, Ming Xiao, Lu Feng, Chengcan Yang, Liang Ouyang

Acta Pharm Sin B· October 2021

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Discovery, Synthesis, and Evaluation of Highly Selective Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) Inhibitor for the Potential Treatment of Metastatic Triple-Negative Breast Cancer.
Yang Li, Gaoxia Yang, Jifa Zhang, Pan Tang, Chengcan Yang, Liang Ouyang

J Med Chem· August 2021

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Targeting Autophagy-Related Epigenetic Regulators for Cancer Drug Discovery.
Yang Li, Gaoxia Yang, Chengcan Yang, Pan Tang, Juncheng Chen, Liang Ouyang

J Med Chem· August 2021

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Identification and optimization of 3-bromo-N'-(4-hydroxybenzylidene)-4-methylbenzohydrazide derivatives as mTOR inhibitors that induce autophagic cell death and apoptosis in triple-negative breast cancer.
Tian Xu, Jifa Zhang, Chengcan Yang, Ryszard Pluta, Guan Wang, Liang Ouyang

Eur J Med Chem· July 2021

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Activated KCNQ1 channel promotes fibrogenic response in hereditary gingival fibromatosis via clustering and activation of Ras.
Qian Gao, Chengcan Yang, Liuyan Meng, Ziming Wang, Dong Chen, Kai Yang

J Periodontal Res· June 2021

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Folate-mediated one-carbon metabolism: a targeting strategy in cancer therapy.
Chengcan Yang, Jifa Zhang, Minru Liao, Yushang Yang, Yuxi Wang, Liang Ouyang

Drug Discov Today· March 2021

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