Publications by authors named "Chengguo Xing"

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An LC-MS/MS Method for the Quantification of Tobacco-Specific Carcinogen Protein Adducts.
Breanne Freeman, Chengguo Xing

Chem Res Toxicol· September 2025

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Chemical knockdown of Keap1 and homoPROTAC-ing allergic rhinitis.
Jianyu Yan, Tianyu Wang, Ruizhi Yu, Lijuan Xu, Hongming Shao, Chengguo Xing

Acta Pharm Sin B· August 2025

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A Bayesian framework for genome-wide circadian rhythmicity biomarker detection.
Haocheng Ding, Lingsong Meng, Yutao Zhang, Andrew J Bryant, Chengguo Xing

Brief Bioinform· August 2025

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Design of anti-depressant phosphodiester amino acidic Keap1-Nrf2 protein-protein interaction inhibitors.
Yi Sun, Jue Wang, Wenxin Ding, Qingqing Qin, Rui Wang, Chengguo Xing

Redox Biol· May 2025

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An LC-MS/MS method for the quantification of tobacco-specific carcinogen protein adducts.
Breanne Freeman, Chengguo Xing

bioRxiv· April 2025

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The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and insomnia: study protocol for a randomized clinical trial.
Chengguo Xing, John Malaty, Melissa Bou Malham, Frank A Orlando, Allison Lynch

BMC Complement Med Ther· December 2024

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Flavokavains A- and B-Free Kava Enhances Resilience against the Adverse Health Effects of Tobacco Smoke in Mice.
Tengfei Bian, Allison Lynch, Kayleigh Ballas, Jessica Mamallapalli, Breanne Freeman, Chengguo Xing

ACS Pharmacol Transl Sci· November 2024

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CosinorTest: An R Shiny App for Cosinor-model-based circadian and differential analysis in transcriptomic applications.
Haocheng Ding, Yutao Zhang, Lingsong Meng, Chengguo Xing, Karyn A Esser

bioRxiv· November 2024

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A Bayesian Framework for Genome-wide Circadian Rhythmicity Biomarker Detection.
Haocheng Ding, Lingsong Meng, Yutao Zhang, Andrew J Bryant, Chengguo Xing

bioRxiv· October 2024

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One-Week Kava Dietary Supplementation Increases Both Urinary - and -Glucuronides of NNAL, a Lung Carcinogen Major Metabolite, among Smokers.
Qi Hu, Zhixin Tang, Allison Lynch, Breanne Freeman, Naomi Fujioka, Chengguo Xing

Chem Res Toxicol· September 2024

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AB-free kava enhances resilience against the adverse health effects of tobacco smoke in mice.
Tengfei Bian, Allison Lynch, Kayleigh Ballas, Jessica Mamallapalli, Breanne Freeman, Chengguo Xing

bioRxiv· June 2024

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Diallyl Disulfide Blocks Cigarette Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Lung Tumorigenesis Activation of the Nrf2 Antioxidant System and Suppression of NF-κB Inflammatory Response.
Jiahui Tian, Wenli Zhao, Yanran Wu, Ying Shi, Jianqiang Yu, Chengguo Xing

J Agric Food Chem· November 2023

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A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease.
Yi Sun, Lijuan Xu, Dongpeng Zheng, Jue Wang, Guodong Liu, Chengguo Xing

Redox Biol· August 2023

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Fragment-Based Discovery of Azocyclic Alkyl Naphthalenesulfonamides as Keap1-Nrf2 Inhibitors for Acute Lung Injury Treatment.
Jianyu Yan, Yue Li, Li Ding, Ruilin Hou, Chengguo Xing

J Med Chem· June 2023

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ROS-mediated SRMS activation confers platinum resistance in ovarian cancer.
Yunhan Jiang, Lina Song, Yizhu Lin, Pawel Nowialis, Qiongmei Gao, Chengguo Xing

Oncogene· May 2023

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Opportunities and Challenges of Kava in Lung Cancer Prevention.
Breanne Freeman, Jessica Mamallapalli, Tengfei Bian, Kayleigh Ballas, Allison Lynch, Chengguo Xing

Int J Mol Sci· May 2023

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Targeting Receptor-Interacting Protein Kinase 1 by Novel Benzothiazole Derivatives: Treatment of Acute Lung Injury through the Necroptosis Pathway.
Xinqi Zhang, Qianyu Han, Ruilin Hou, Lijuan Xu, Wannian Zhang, Chengguo Xing

J Med Chem· April 2023

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Investigating miR-9 as a mediator in laryngeal cancer health disparities.
Christina Gobin, Samuel Inkabi, Chayil C Lattimore, Tongjun Gu, James N Menefee, Chengguo Xing

Front Oncol· April 2023

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Profiling of the chemical space on the phenyl group of substituted benzothiazole RIPK3 inhibitors.
Yue Xu, Caiquan Liang, Wannian Zhang, Jianqiang Yu, Chengguo Xing

Bioorg Chem· February 2023

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Reducing tobacco-associated lung cancer risk: a study protocol for a randomized clinical trial of AB-free kava.
Chengguo Xing, John Malaty, Melissa Bou Malham, Anna Maria Abi Nehme, Breanne Freeman

Trials· January 2023

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Dietary Phytochemicals as Potential Chemopreventive Agents against Tobacco-Induced Lung Carcinogenesis.
Yan Ding, Ruilin Hou, Jianqiang Yu, Chengguo Xing, Chunlin Zhuang

Nutrients· January 2023

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Clinical pharmacokinetics of kavalactones after oral dosing of standardized kava extract in healthy volunteers.
Siva Rama Raju Kanumuri, Jessica Mamallapalli, Robyn Nelson, Christopher R McCurdy, Carol A Mathews, Chengguo Xing

J Ethnopharmacol· October 2022

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LKB1 phosphorylation and deactivation in lung cancer by NNAL, a metabolite of tobacco-specific carcinogen, in an isomer-dependent manner.
Tengfei Bian, Yuzhi Wang, Jordy F Botello, Qi Hu, Yunhan Jiang, Chengguo Xing

Oncogene· August 2022

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: Signature Compounds, Anticancer, Analgesic, Neuroprotective and Other Activities, and the Clinical Translation Challenges.
Junxuan Lü, Cheng Jiang, Todd D Schell, Monika Joshi, Jay D Raman, Chengguo Xing

Am J Chin Med· August 2022

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Crystallography-Guided Optimizations of the Keap1-Nrf2 Inhibitors on the Solvent Exposed Region: From Symmetric to Asymmetric Naphthalenesulfonamides.
Guodong Liu, Ruilin Hou, Lijuan Xu, Xinqi Zhang, Jianyu Yan, Chengguo Xing

J Med Chem· June 2022

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