Publications by authors named "Chenghao Xuan"

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Author Correction: Identification of a non-inhibitory aptameric ligand to CRL2 E3 ligase for targeted protein degradation.
Zhihao Yang, Miao Chen, Ruixin Ge, Ping Zhou, Wei Pan, Chenghao Xuan

Nat Commun· December 2025

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ATF7IP inhibits Sorafenib-induced ferroptosis in hepatocellular carcinoma cells by inhibiting CYB5R2 transcription and stabilizing PARK7 protein.
Yijie Su, Sirui Huang, Yang Duan, Liang Zhang, Shengyun Feng, Chenghao Xuan

Redox Biol· September 2025

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Dot1L Promotes Stress-Induced Cardiac Hypertrophy in Mice via Tbx6.
Jiao Liu, Yuxuan Jin, Shengkai Zuo, Chengsen Mu, Bei Wang, Chenghao Xuan

Circ Res· August 2025

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Erratum: A CRISPR/Cas9 library screening identifies CARM1 as a critical inhibitor of ferroptosis in hepatocellular carcinoma cells.
Yiming Cheng, Xiaochen Wang, Shuyu Huang, Liang Zhang, Bei Lan, Xuanyuan Li, Yanxuan Guo, Chenghao Xuan

Mol Ther Nucleic Acids· June 2025

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USP22 promotes the proliferation and Sorafenib resistance of hepatocellular carcinoma cells via its deubiquitinase activity.
Xiaochen Wang, Yijie Su, Bei Lan, Xuanyuan Li, Bodi Zhang, Chenghao Xuan

Clin Transl Med· May 2025

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DNA nanoflower Oligo-PROTAC for targeted degradation of FUS to treat neurodegenerative diseases.
Ruixin Ge, Miao Chen, Sijin Wu, Sirui Huang, Ping Zhou, Chenghao Xuan

Nat Commun· May 2025

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Identification of a non-inhibitory aptameric ligand to CRL2 E3 ligase for targeted protein degradation.
Zhihao Yang, Miao Chen, Ruixin Ge, Ping Zhou, Wei Pan, Chenghao Xuan

Nat Commun· March 2025

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Corrigendum to "Dimerization of ZIP promotes its transcriptional repressive function and biological activity" [Int. J. Biochem. Cell Biol. 44 (2012) 886-895].
Bin Gui, Xiao Han, Yu Zhang, Jing Liang, Dandan Wang, Chenghao Xuan

Int J Biochem Cell Biol· February 2025

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CBX4 plays a bidirectional role in transcriptional regulation and lung adenocarcinoma progression.
Ran Zhao, Yanxuan Guo, Linlin Zhang, Zhiyong Huang, Xuanyuan Li, Chenghao Xuan

Cell Death Dis· May 2024

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InPACT: a computational method for accurate characterization of intronic polyadenylation from RNA sequencing data.
Xiaochuan Liu, Hao Chen, Zekun Li, Xiaoxiao Yang, Wen Jin, Chenghao Xuan

Nat Commun· March 2024

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A CRISPR-Cas9 library screening identifies CARM1 as a critical inhibitor of ferroptosis in hepatocellular carcinoma cells.
Yiming Cheng, Xiaochen Wang, Shuyu Huang, Liang Zhang, Bei Lan, Xuanyuan Li, Yanxuan Guo, Chenghao Xuan

Mol Ther Nucleic Acids· December 2023

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Leveraging aptamers for targeted protein degradation.
Zhihao Yang, Qiuxiang Pang, Jun Zhou, Chenghao Xuan, Songbo Xie

Trends Pharmacol Sci· November 2023

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CBX8 promotes lung adenocarcinoma growth and metastasis through transcriptional repression of CDKN2C and SCEL.
Hao Chen, Yijie Su, Lihong Yang, Lishan Xi, Xuanyuan Li, Chenghao Xuan

J Cell Physiol· November 2023

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HDAC6 deacetylates IDH1 to promote the homeostasis of hematopoietic stem and progenitor cells.
Jia Yang, Yang Liu, Hanxiao Yin, Songbo Xie, Linlin Zhang, Chenghao Xuan

EMBO Rep· October 2023

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CBX8 Together with SET Facilitates Ovarian Carcinoma Growth and Metastasis by Suppressing the Transcription of SUSD2.
Yanjie Wu, Yang Duan, Xuanyuan Li, Ran Zhao, Bei Lan, Chenghao Xuan

Mol Cancer Res· November 2022

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A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Xiao Liang, Jun Xiao, Xuzichao Li, Yujie Liu, Yao Lu, Chenghao Xuan

Nat Chem Biol· November 2022

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Integrated analysis of genes encoding ATP-dependent chromatin remodellers identifies CHD7 as a potential target for colorectal cancer therapy.
Xingyan Zhang, Yaoyao Zhou, Zhenyu Shi, Zhenfeng Liu, Hao Chen, Xuanyuan Li, Chenghao Xuan

Clin Transl Med· July 2022

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CBX2 and EZH2 cooperatively promote the growth and metastasis of lung adenocarcinoma.
Fei-Fei Hu, Hao Chen, Yang Duan, Bei Lan, Chun-Jie Liu, Chenghao Xuan

Mol Ther Nucleic Acids· March 2022

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Ultrafast and scalable variant annotation and prioritization with big functional genomics data.
Dandan Huang, Xianfu Yi, Yao Zhou, Hongcheng Yao, Hang Xu, Chenghao Xuan

Genome Res· December 2020

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JMJD6 modulates DNA damage response through downregulating H4K16ac independently of its enzymatic activity.
Dawei Huo, Hao Chen, Yiming Cheng, Xin Song, Kai Zhang, Chenghao Xuan

Cell Death Differ· March 2020

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Disruptor of telomeric silencing 1-like (DOT1L) is involved in breast cancer metastasis via transcriptional regulation of MALAT1 and ZEB2.
Yang Duan, Xingyan Zhang, Lihong Yang, Xu Dong, Zhanye Zheng, Chenghao Xuan

J Genet Genomics· December 2019

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GWAS4D: multidimensional analysis of context-specific regulatory variant for human complex diseases and traits.
Dandan Huang, Xianfu Yi, Shijie Zhang, Zhanye Zheng, Panwen Wang, Chenghao Xuan

Nucleic Acids Res· July 2018

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Exploring genetic associations with ceRNA regulation in the human genome.
Mulin Jun Li, Jian Zhang, Qian Liang, Chenghao Xuan, Jiexing Wu

Nucleic Acids Res· June 2017

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FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis.
Lin Shan, Xing Zhou, Xinhua Liu, Yue Wang, Dongxue Su, Chenghao Xuan

Cancer Cell· November 2016

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Corrigendum: Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5.
Yang Duan, Dawei Huo, Jie Gao, Heng Wu, Zheng Ye, Chenghao Xuan

Nat Commun· November 2016

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