Publications by authors named "Chengwu Zeng"

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Synergistic effects of BET inhibitors and ferroptosis inducers via targeted inhibition of the BRD4/c-Myc/NRF2 pathway in AML.
Mengjun Zhong, Shuxin Zhong, Kangjie Qiu, Xueting Peng, Xin Liu, Chengwu Zeng

Eur J Pharmacol· July 2025

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mA/IGF2BP3-driven serine biosynthesis fuels AML stemness and metabolic vulnerability.
Feng Huang, Yushuai Wang, Xiuxin Zhang, Weiwei Gao, Jingwen Li, Chengwu Zeng

Nat Commun· May 2025

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Single-Cell Multiomics Reveals TCR Clonotype-Specific Phenotype and Stemness Heterogeneity of T-ALL Cells.
Songnan Sui, Xiaolei Wei, Yue Zhu, Qiuyue Feng, Xianfeng Zha, Chengwu Zeng

Cell Prolif· April 2025

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Inhibition of TOX exerts anti-tumor effects in acute myeloid leukemia by upregulating IRF7 expression.
Shuxin Huang, Zhixi Chen, Shuxin Zhong, Yikai Zhang, Chengwu Zeng

Eur J Pharmacol· January 2025

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YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies.
Zhenhua Chen, Chengwu Zeng, Lu Yang, Yuan Che, Meiling Chen

Cell· January 2025

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Aptamer sgc8-Modified PAMAM Nanoparticles for Targeted siRNA Delivery to Inhibit BCL11B in T-Cell Acute Lymphoblastic Leukemia.
Xiangbo Zeng, Dingrui Nie, Zhen Liu, Xueting Peng, Xianfeng Wang, Chengwu Zeng

Int J Nanomedicine· November 2024

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BRD4 inhibitor reduces exhaustion and blocks terminal differentiation in CAR-T cells by modulating BATF and EGR1.
Songnan Sui, Mengjun Zhong, Shuxin Zhong, Xueting Peng, Lipeng Mao, Chengwu Zeng

Biomark Res· October 2024

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Combined targeting of GPX4 and BCR-ABL tyrosine kinase selectively compromises BCR-ABL+ leukemia stem cells.
Chengwu Zeng, Dingrui Nie, Xianfeng Wang, Shuxin Zhong, Xiangbo Zeng

Mol Cancer· October 2024

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BET Inhibitor JQ1 Selectively Reduce Tregs by Upregulating STAT3 and Suppressing PD-1 Expression in Patients with Multiple Myeloma.
Youxue Huang, Mengjun Zhong, Rili Gao, Xianfeng Wang, Shuxin Zhong, Chengwu Zeng

Adv Biol (Weinh)· July 2024

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Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling.
Meiling Chen, Chao Shen, Yi Chen, Zhenhua Chen, Keren Zhou, Chengwu Zeng

Cell Rep Med· July 2024

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Editorial: Immunologic tumor microenvironment modulators for turning "cold" tumors to "hot" tumors.
Mazdak Ganjalıkhani-Hakemi, Gulderen Yanikkaya Demirel, Xin He, Chengwu Zeng

Front Immunol· May 2024

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Single-cell RNA sequencing gene signatures for classifying and scoring exhausted CD8 T cells in B-cell acute lymphoblastic leukaemia.
Songnan Sui, Yun Tian, Xiaofang Wang, Chengwu Zeng, Oscar Junhong Luo

Cell Prolif· March 2024

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T-cell lymphoma patient harboring BCL11B mutations had favorable overall survival.
Cunte Chen, Ling Huang, Sichu Liu, Xinmiao Jiang, Feili Chen, Xiangbo Zeng, Chengwu Zeng

Asia Pac J Clin Oncol· February 2024

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Higher 13-Gene-Estimated TMB Detected from Plasma ctDNA is Associated with Worse Outcome for T-Cell Lymphoma Patients.
Cunte Chen, Ling Huang, Zheng Chen, Qiuxiang Ou, Sichu Liu, Chengwu Zeng

Adv Biol (Weinh)· December 2023

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CASP1 is a target for combination therapy in pancreatic cancer.
Xianfeng Wang, Zheng Chen, Dingrui Nie, Xiangbo Zeng, Mengjun Zhong, Chengwu Zeng

Eur J Pharmacol· December 2023

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Mutations Are Associated with Higher CD8+ T-Cell Percentage and Favorable Clinical Outcomes in Patients with T-Cell Acute Lymphoblastic Leukemia.
Cunte Chen, Yuping Zhang, Xiangbo Zeng, Chengwu Zeng, Grzegorz K Przybylski

Clin Med Insights Oncol· December 2023

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Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis.
Xin Liu, Shuxin Zhong, Kangjie Qiu, Xi Chen, Weiyue Wu, Chengwu Zeng

Exp Hematol Oncol· May 2023

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High expression of LOC541471, GDAP1, SOD1, and STK25 is associated with poor overall survival of patients with acute myeloid leukemia.
Xibao Yu, Cunte Chen, Yanyun Hu, Kehan Li, Yikai Zhang, Yixin Zeng, Chengwu Zeng

Cancer Med· April 2023

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Overexpression of CASP1 triggers acute promyelocytic leukemia cell pyroptosis and differentiation.
Xibao Yu, Xin Liu, Xuan Liu, Shuang Jin, Mengjun Zhong, Xiangbo Zeng, Chengwu Zeng

Eur J Pharmacol· April 2023

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TNFAIP3 mutation is an independent poor overall survival factor for patients with T-cell acute lymphoblastic leukemia.
Cunte Chen, Lingling Zhou, Lihua Zhu, Gengxin Luo, Liang Wang, Chengwu Zeng

Cancer Med· February 2023

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BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia.
Mengjun Zhong, Rili Gao, Ruocong Zhao, Youxue Huang, Cunte Chen, Chengwu Zeng

Cell Death Dis· August 2022

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Low Expression of CD5 and CD6 Is Associated with Poor Overall Survival for Patients with T-Cell Malignancies.
Songnan Sui, Zhiyan Li, Jiaxiong Tan, Liang Wang, Gengxin Luo, Chengwu Zeng

J Oncol· August 2022

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Correction to: BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia.
Mengjun Zhong, Rili Gao, Ruocong Zhao, Youxue Huang, Cunte Chen, Chengwu Zeng

Cell Death Dis· August 2022

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Current insight into the regulation of PD-L1 in cancer.
Zhuandi Liu, Xibao Yu, Ling Xu, Yangqiu Li, Chengwu Zeng

Exp Hematol Oncol· July 2022

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Disulfiram, an aldehyde dehydrogenase inhibitor, works as a potent drug against sepsis and cancer via NETosis, pyroptosis, apoptosis, ferroptosis, and cuproptosis.
Dingrui Nie, Cunte Chen, Yangqiu Li, Chengwu Zeng

Blood Sci· July 2022

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