Publications by authors named "Chengxiang Qiu"

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Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis.
Ki Wung Chung, Poonam Dhillon, Shizheng Huang, Xin Sheng, Rojesh Shrestha, Chengxiang Qiu, Brett A Kaufman, Jihwan Park, Liming Pei, Joseph Baur

Cell Metab· October 2019

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Single-cell, multi-region profiling of the macaque brain across the lifespan.
Wei Yang, Kelsi L Watkins, Alex R DeCasien, Mary B O'Neill, Martin O Bohlen, Chengxiang Qiu

bioRxiv· November 2025

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Multicondition and multimodal temporal profile inference during mouse embryonic development.
Ran Zhang, Chengxiang Qiu, Galina N Filippova, Gang Li, Jay Shendure

Genome Res· October 2025

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Dual-patterned pluripotent stem cells self-organize into a human embryo model with extended anterior-posterior patterning.
Zukai Liu, Chengxiang Qiu, Connor A Kubo, Stella Xu, Riza M Daza

bioRxiv· September 2025

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Barcoded monoclonal embryoids are a potential solution to confounding bottlenecks in mosaic organoid screens.
Samuel G Regalado, Chengxiang Qiu, Jean-Benoît Lalanne, Beth K Martin, Madeleine Duran

bioRxiv· July 2025

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Lineage recording in monoclonal gastruloids reveals heritable modes of early development.
Samuel G Regalado, Chengxiang Qiu, Sanjay Kottapalli, Beth K Martin, Wei Chen

bioRxiv· July 2025

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Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.
Hongbo Liu, Amin Abedini, Eunji Ha, Ziyuan Ma, Xin Sheng, Chengxiang Qiu

Science· February 2025

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Retinoic acid induces human gastruloids with posterior embryo-like structures.
Nobuhiko Hamazaki, Wei Yang, Connor A Kubo, Chengxiang Qiu, Beth K Martin

Nat Cell Biol· October 2024

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Multi-condition and multi-modal temporal profile inference during mouse embryonic development.
Ran Zhang, Chengxiang Qiu, Gala Filippova, Gang Li, Jay Shendure

bioRxiv· September 2024

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Symbolic recording of signalling and cis-regulatory element activity to DNA.
Wei Chen, Junhong Choi, Xiaoyi Li, Jenny F Nathans, Beth Martin, Chengxiang Qiu

Nature· August 2024

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Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome.
H Nayanga Thirimanne, Damian Almiron-Bonnin, Nicholas Nuechterlein, Sonali Arora, Matt Jensen, Chengxiang Qiu

Cell Genom· June 2024

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A single-cell time-lapse of mouse prenatal development from gastrula to birth.
Chengxiang Qiu, Beth K Martin, Ian C Welsh, Riza M Daza, Truc-Mai Le

Nature· February 2024

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Induction and staging of human gastruloids with neural tube, segmented somites & advanced cell types.
Nobuhiko Hamazaki, Wei Yang, Connor Kubo, Chengxiang Qiu, Beth K Martin

bioRxiv· February 2024

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Single-cell, whole-embryo phenotyping of mammalian developmental disorders.
Xingfan Huang, Jana Henck, Chengxiang Qiu, Varun K A Sreenivasan, Saranya Balachandran

Nature· November 2023

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A single-cell transcriptional timelapse of mouse embryonic development, from gastrula to pup.
Chengxiang Qiu, Beth K Martin, Ian C Welsh, Riza M Daza, Truc-Mai Le

bioRxiv· April 2023

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Optimized single-nucleus transcriptional profiling by combinatorial indexing.
Beth K Martin, Chengxiang Qiu, Eva Nichols, Melissa Phung, Rula Green-Gladden

Nat Protoc· January 2023

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Embryo model completes gastrulation to neurulation and organogenesis.
Gianluca Amadei, Charlotte E Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld

Nature· October 2022

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Systematic reconstruction of cellular trajectories across mouse embryogenesis.
Chengxiang Qiu, Junyue Cao, Beth K Martin, Tony Li, Ian C Welsh

Nat Genet· March 2022

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Genome-wide association studies identify the role of caspase-9 in kidney disease.
Tomohito Doke, Shizheng Huang, Chengxiang Qiu, Xin Sheng, Matthew Seasock

Sci Adv· November 2021

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Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments.
Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu

Nat Genet· September 2021

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A continuous model of early mammalian development.
Chengxiang Qiu, Jay Shendure

Nature· May 2021

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Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis.
Tomohito Doke, Shizheng Huang, Chengxiang Qiu, Hongbo Liu, Yuting Guan

J Clin Invest· May 2021

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Kidney disease genetic risk variants alter lysosomal beta-mannosidase () expression and disease severity.
Xiangchen Gu, Hongliu Yang, Xin Sheng, Yi-An Ko, Chengxiang Qiu

Sci Transl Med· January 2021

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Systematic integrated analysis of genetic and epigenetic variation in diabetic kidney disease.
Xin Sheng, Chengxiang Qiu, Hongbo Liu, Caroline Gluck, Jesse Y Hsu

Proc Natl Acad Sci U S A· November 2020

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Loss of IL-27Rα Results in Enhanced Tubulointerstitial Fibrosis Associated with Elevated Th17 Responses.
Gaia M Coppock, Lillian R Aronson, Jihwan Park, Chengxiang Qiu, Jeongho Park

J Immunol· July 2020

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Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways.
Archna Bajaj, Andrea Ihegword, Chengxiang Qiu, Aeron M Small, Wei-Qi Wei

Kidney Int· May 2020

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