Publications by authors named "Chengyuan Lin"

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Berberine suppresses colon inflammation via integrated modulation of host metabolism, microbial ecology, and innate immune signaling.
Yaqin Xiao, Xueying Li, Yuanyuan Fang, Miao Guo, Mingju Shui, Chengyuan Lin

Theranostics· December 2025

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Critical Role in Structural Optimization and Activation of CAU-23 Membranes for CO Separation.
Chia-Hui Chuang, Jeongho Seong, Li-Wei Hsiao, Cheng-Yuan Lin, Cheng-Liang Liu

Small· November 2025

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SARS-CoV-2 Spike Protein as a Target of the COVID-19 Vaccine Disrupts Insulin Signaling in Type 2 Diabetes.
Lixiang Zhai, Min Zhuang, Hoi Ki Wong, Chengyuan Lin, Haoran Ying, Jialing Zhang

MedComm (2020)· November 2025

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Macrophage-Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation.
Yiqi Xu, Jingchun Shi, Heung-Lam Mok, Cheng Lyu, Junbang Chen, Chengyuan Lin

Adv Sci (Weinh)· September 2025

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Butyrate-producing commensal bacteria mediates the efficacy of herbal medicine JCM-16021 on abdominal pain in diarrhea-predominant irritable bowel syndrome: a randomized clinical trial.
Lixiang Zhai, Ya Zheng, Cho Wing Lo, Shujun Xu, Xuanting Jiang, Linda L D Zhong, Zhixiu Lin, Chengyuan Lin, Ling Zhao

Phytomedicine· September 2025

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Gut microbe-derived aromatic trace amines mediate individual variability in response to herbal medicine CDD-2101 for functional constipation.
Shifa Ruan, Yaqi Li, Ziwan Ning, Yunlyu Li, Qin Liu, Lin Zhu, Chengyuan Lin

Pharmacol Res· July 2025

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Multi-kingdom microbiota analysis reveals bacteria-viral interplay in IBS with depression and anxiety.
Qin Liu, Wenyu Fang, Ping Zheng, Shicai Xie, Xuanting Jiang, Ling Zhao, Lin Lu, Chengyuan Lin

NPJ Biofilms Microbiomes· July 2025

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Tolerogenic dendritic cell-mediated regulatory T cell differentiation by Chinese herbal formulation attenuates colitis progression.
Chunhua Huang, Cheng Lyu, Heung-Lam Mok, Yiqi Xu, Ka-Wing Cheng, Lin Zhu, Chengyuan Lin

J Adv Res· April 2025

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Green valorization of Chaenomelis Fructus agro-industrial by-products as a source of phenolics: Ultrasound-assisted extraction, adsorptive enrichment and quality control.
Mengyang Hou, Yujuan Zhou, Chengyuan Lin, Jingchun Shi, Huidan Hou, Lin Zhu

Food Chem· April 2025

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Phenolics from Chaenomeles speciosa leaves: Ionic liquid-based ultrasound-assisted extraction, adsorptive purification, UPLC-QqQ-MS/MS quantification, and bioactivity assessment.
Mengyang Hou, Chengyuan Lin, Lin Zhu, Zhaoxiang Bian

Ultrason Sonochem· March 2025

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Ultrasound-assisted extraction of triterpenoids from Chaenomeles speciosa leaves: Process optimization, adsorptive enrichment, chemical profiling, and protection against ulcerative colitis.
Mengyang Hou, Jingchun Shi, Chengyuan Lin, Lin Zhu, Zhaoxiang Bian

Ultrason Sonochem· December 2024

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Modified Zhenwu Decoction improved intestinal barrier function of experimental colitis through activation of sGC-mediated cGMP/PKG signaling.
Yiqi Xu, Chunhua Huang, Hengyue Xu, Jiaruo Xu, Ka Wing Cheng, Lin Zhu, Chengyuan Lin

J Ethnopharmacol· November 2024

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Integrated metabolomics and serum-feces pharmacochemistry-based network pharmacology to reveal the mechanisms of an herbal prescription against ulcerative colitis.
Ka Wing Cheng, Jingchun Shi, Chunhua Huang, Hor Yue Tan, Ziwan Ning, Chengyuan Lin, Lin Zhu

Comput Biol Med· August 2024

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Modified Zhenwu Decoction suppresses chronic colitis via targeting macrophage CCR2/Fyn/p38 MAPK signaling axis.
Heung Lam Mok, Ka Wing Cheng, Yiqi Xu, Chunhua Huang, Cheng Lyu, Lin Zhu, Chengyuan Lin

Phytomedicine· July 2024

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One-step enrichment of phenolics from Chaenomeles speciosa (Sweet) Nakai fruit using macroporous resin: Adsorption/desorption characteristics, process optimization and UPLC-QqQ-MS/MS-based quantification.
Mengyang Hou, Chengyuan Lin, Yanhua Ma, Jingchun Shi, Jie Liu, Lin Zhu

Food Chem· May 2024

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The double-edged sword effect of indigo naturalis.
Yiqi Xu, Chengyuan Lin, Hor-Yue Tan, Zhao-Xiang Bian

Food Chem Toxicol· March 2024

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Production and characterization of single-chain variable fragment antibodies targeting the breast cancer tumor marker nectin-4.
Ching-Hsuan Liu, Sy-Jye Leu, Chi-Hsin Lee, Cheng-Yuan Lin, Wei-Chu Wang, Liang-Tzung Lin

Front Immunol· January 2024

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Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome.
Lixiang Zhai, Haitao Xiao, Chengyuan Lin, Hoi Leong Xavier Wong, Yan Y Lam, Ling Zhao

Nat Commun· August 2023

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Altered gut microbiota-host bile acid metabolism in IBS-D patients with liver depression and spleen deficiency pattern.
Liqing Du, Zhaozhou Zhang, Lixiang Zhai, Shujun Xu, Wei Yang, Chengyuan Lin, Linda L D Zhong, Ling Zhao

Chin Med· July 2023

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Aqueous cinnamon extract ameliorates bowel dysfunction and enteric 5-HT synthesis in IBS rats.
Lijuan Yu, Chunhua Huang, Wei Yang, Zhenxing Ren, Lifeng Li, Chengyuan Lin, Ling Zhao

Front Pharmacol· January 2023

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Alkaloid from diels root against gastrointestinal cancer: Acetoxytabernosine inhibits apoptosis in hepatocellular carcinoma cells.
Qi Lai, Chun-Ju Yang, Qi Zhang, Min Zhuang, Yan-Hua Ma, Cheng-Yuan Lin, Jun-Lin Yin

Front Pharmacol· January 2023

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Mechanisms for Bile Acids CDCA- and DCA-Stimulated Hepatic Spexin Expression.
Qi Lai, Yanhua Ma, Jin Bai, Min Zhuang, Shaofei Pei, Junlin Yin, Chengyuan Lin

Cells· July 2022

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Therapeutic effects and mechanisms of Zhen-Wu-Bu-Qi Decoction on dextran sulfate sodium-induced chronic colitis in mice assessed by multi-omics approaches.
Lixiang Zhai, Jiao Peng, Min Zhuang, Yao-Yao Chang, Ka Wing Cheng, Chengyuan Lin

Phytomedicine· May 2022

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Translation initiation landscape profiling reveals hidden open-reading frames required for the pathogenesis of tomato yellow leaf curl Thailand virus.
Ching-Wen Chiu, Ya-Ru Li, Cheng-Yuan Lin, Hsin-Hung Yeh, Ming-Jung Liu

Plant Cell· April 2022

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A Novel Model for Landslide Displacement Prediction Based on EDR Selection and Multi-Swarm Intelligence Optimization Algorithm.
Junrong Zhang, Huiming Tang, Dwayne D Tannant, Chengyuan Lin, Ding Xia

Sensors (Basel)· December 2021

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