Publications by authors named "Cheolhee Won"

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A First-In-Human Phase 1 Study to Evaluate the Safety and Tolerability of LEM-S401, a Novel siRNA-DegradaBALL Drug Targeting CTGF in Healthy Adults.
Ha-Yeon Kim, Jaeso Cho, Min Kyu Park, Dal-Hee Min, Jun Gi Hwang, Cheolhee Won

Clin Transl Sci· April 2025

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A Single-Dose mRNA Vaccine Employing Porous Silica Nanoparticles Induces Robust Immune Responses Against the Zika Virus.
Hojeong Shin, Seounghun Kang, Cheolhee Won, Dal-Hee Min

Adv Sci (Weinh)· September 2024

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Enhanced Local Delivery of Engineered IL-2 mRNA by Porous Silica Nanoparticles to Promote Effective Antitumor Immunity.
Hojeong Shin, Seounghun Kang, Cheolhee Won, Dal-Hee Min

ACS Nano· September 2023

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Development of a Cancer Nanovaccine to Induce Antigen-specific Immune Responses Based on Large-Sized Porous Silica Nanoparticles.
Hojeong Shin, Seounghun Kang, Se-Youl Chae, Cheolhee Won, Dal-Hee Min

ACS Appl Mater Interfaces· March 2023

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Multifunctional synthetic nano-chaperone for peptide folding and intracellular delivery.
Il-Soo Park, Seongchan Kim, Yeajee Yim, Ginam Park, Jinahn Choi, Cheolhee Won

Nat Commun· August 2022

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Nanoparticle delivery of recombinant IL-2 (BALLkine-2) achieves durable tumor control with less systemic adverse effects in cancer immunotherapy.
Jun Kim, Seounghun Kang, Kyoung Won Kim, Myeong-Gang Heo, Dae-In Park, Cheolhee Won

Biomaterials· January 2022

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Non-viral, direct neuronal reprogramming from human fibroblast using a polymer-functionalized nanodot.
Se-Jin Park, Hojeong Shin, Cheolhee Won, Dal-Hee Min

Nanomedicine· February 2021

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Discovery of direct-acting antiviral agents with a graphene-based fluorescent nanosensor.
Se-Jin Park, Jungho Kim, Seounghun Kang, Hyung Jin Cha, Hojeong Shin, Cheolhee Won

Sci Adv· May 2020

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RNAi nanotherapy for fibrosis: highly durable knockdown of CTGF/CCN-2 using siRNA-DegradaBALL (LEM-S401) to treat skin fibrotic diseases.
Seounghun Kang, Jun Kim, Minchul Ahn, Jungho Kim, Myeong-Gang Heo, Cheolhee Won

Nanoscale· March 2020

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High-throughput chemical screening to discover new modulators of microRNA expression in living cells by using graphene-based biosensor.
Soo-Ryoon Ryoo, Yeajee Yim, Young-Kwan Kim, Il-Soo Park, Hee-Kyung Na, Cheolhee Won

Sci Rep· July 2018

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Highly Efficient and Rapid Neural Differentiation of Mouse Embryonic Stem Cells Based on Retinoic Acid Encapsulated Porous Nanoparticle.
Se-Jin Park, Seongchan Kim, Sung-Yon Kim, Noo Li Jeon, Joon Myong Song, Cheolhee Won

ACS Appl Mater Interfaces· October 2017

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Signal transducer and activator of transcription 3-mediated CD133 up-regulation contributes to promotion of hepatocellular carcinoma.
Cheolhee Won, Byung-Hak Kim, Eun Hee Yi, Kyung-Ju Choi, Eun-Kyung Kim, Won-Il Jeong

Hepatology· October 2015

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Direct cellular delivery of human proteasomes to delay tau aggregation.
Dong Hoon Han, Hee-Kyung Na, Won Hoon Choi, Jung Hoon Lee, Yun Kyung Kim, Cheolhee Won

Nat Commun· December 2014

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Snail1 induced in breast cancer cells in 3D collagen I gel environment suppresses cortactin and impairs effective invadopodia formation.
Mi-Sook Lee, Sudong Kim, Baek Gil Kim, Cheolhee Won, Seo Hee Nam

Biochim Biophys Acta· September 2014

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Signal transducer and activator of transcription 3 (Stat3) contributes to T-cell homeostasis by regulating pro-survival Bcl-2 family genes.
Jin-Ku Lee, Cheolhee Won, Eun Hee Yi, Seung-Hyeok Seok, Myoung-Hwan Kim

Immunology· November 2013

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Sophoraflavanone G induces apoptosis of human cancer cells by targeting upstream signals of STATs.
Byung-Hak Kim, Cheolhee Won, Yun-Han Lee, Jung Sook Choi, Kum Hee Noh

Biochem Pharmacol· October 2013

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BST-2 is a potential activator of invasion and migration in tamoxifen-resistant breast cancer cells.
Eun Hee Yi, Hyouna Yoo, Kum Hee Noh, Songhee Han, Haeri Lee, Cheolhee Won

Biochem Biophys Res Commun· June 2013

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Simvastatin suppresses RANTES-mediated neutrophilia in polyinosinic-polycytidylic acid-induced pneumonia.
Chang Seok Lee, Eun Hee Yi, Jin-Ku Lee, Cheolhee Won, Young Ju Lee

Eur Respir J· May 2013

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Relative antioxidant activities of quercetin and its structurally related substances and their effects on NF-κB/CRE/AP-1 signaling in murine macrophages.
Byung-Hak Kim, Jung Sook Choi, Eun Hee Yi, Jin-Ku Lee, Cheolhee Won

Mol Cells· May 2013

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α-Enolase expressed on the surfaces of monocytes and macrophages induces robust synovial inflammation in rheumatoid arthritis.
Seyeon Bae, Hyemin Kim, Naeun Lee, Cheolhee Won, Hang-Rae Kim

J Immunol· July 2012

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CADPE suppresses cyclin D1 expression in hepatocellular carcinoma by blocking IL-6-induced STAT3 activation.
Cheolhee Won, Chang Seok Lee, Jin-Ku Lee, Tack-Joong Kim, Kwang-Ho Lee

Anticancer Res· February 2010

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Porcine nuclear transfer using somatic donor cells altered to express male germ cell function.
Sangho Roh, Hye-Yeon Choi, Sang Kyu Park, Cheolhee Won, Bong-Woo Kim

Reprod Fertil Dev· November 2009

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Inhibition of double-stranded RNA-induced inducible nitric oxide synthase expression by fraxinellone and sauchinone in murine microglia.
Chang Seok Lee, Cheolhee Won, Hyouna Yoo, Eun Hee Yi, Yuri Cho

Biol Pharm Bull· November 2009

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Simvastatin acts as an inhibitor of interferon gamma-induced cycloxygenase-2 expression in human THP-1 cells, but not in murine RAW264.7 cells.
Chang Seok Lee, Yong Jae Shin, Cheolhee Won, Yun-Song Lee, Chung-Gyu Park

Biocell· August 2009

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The leading blastomere of the 2-cell stage parthenogenetic porcine embryo contributes to the abembryonic part first.
Sang Kyu Park, Cheolhee Won, Young-Ju Choi, Hoin Kang, Sangho Roh

J Vet Med Sci· May 2009

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